Filtyp
Background: Neuropathological studies have linked tau aggregates to neuronal loss. To describe the spatial distribution of neurofibrillary tangle pathology in post-mortem tissue, Braak staging has been used. The aim of this study was to examine in vivo associations between tau pathology, quantified with [18F]flortaucipir PET in regions corresponding to Braak stages, and atrophy across the Alzheime
In order to identify the signal epitopes of the neuropeptide Y (NPY) molecule, the conformation of the NPY molecule was pertubated by a systematic double D-amino acid replacement of neighbouring residues. These NPY-analogs were examined for receptor affinity and on biological activity. The rat cerebral cortex and hippocampus were used for binding characteristics on Y1 and Y2 binding sites, respect
Importance: The concept of embolic stroke of undetermined source (ESUS) unifies a subgroup of cryptogenic strokes based on neuroimaging, a defined minimum set of diagnostic tests, and exclusion of certain causes. Despite an annual stroke recurrence rate of 5%, little is known about the etiology underlying recurrent stroke after ESUS. Objective: To identify the stroke subtype of recurrent ischemic
Background: Bococizumab is a humanized monoclonal antibody that inhibits proprotein convertase subtilisin-kexin type 9 (PCSK9) and reduces levels of low-density lipoprotein (LDL) cholesterol. We sought to evaluate the efficacy of bococizumab in patients at high cardiovascular risk. Methods: In two parallel, multinational trials with different entry criteria for LDL cholesterol levels, we randomly
Objectives To calculate the normal range for the fetal middle cerebral artery (MCA)/uterine artery pulsatility index (PI) ratio in the third trimester of pregnancy and to assess its value, compared with that of the MCA/umbilical artery PI ratio, in predicting an unfavorable outcome of pregnancies complicated by pre-eclampsia. Methods Doppler blood flow velocimetry of the uterine and umbilical arte
Background: Targeted temperature management is recommended after out-of-hospital cardiac arrest and may be achieved using a variety of cooling devices. This study was conducted to explore the performance and outcomes for intravascular versus surface devices for targeted temperature management after out-of-hospital cardiac arrest. Method: A retrospective analysis of data from the Targeted Temperatu
SAM-uppföljning 2022 SAM-uppföljning 2025 CENTRAL SKYDDSKOMMITTÉ 2026-04-01 LU-gemensamma frågor (AFS 2023:1) Varför är det viktigt att följa upp systematiken? Varför är SAM viktigt…? ”Arbetsmiljöns paradox, arbetsmiljön på LU och på HT-fakulteterna har varit i fokus och prövats på flera olika sätt under 2025. Den ökade polariseringen i samhället är något som återspeglats inom universitetet. Både
BACKGROUND Anterior cruciate ligament (ACL) injury of the knee is common in young active adults and often has severe and sometimes lifelong consequences. The clinical management of this injury remains debated. A prior trial of early versus delayed optional ACL repair showed no differences in outcomes at 2 years. METHODS We present the 11-year follow-up of a randomized clinical trial involving 121
Objective: Analyze the outcomes of endovascular complex abdominal and thoracoabdominal aortic aneurysm repair using the Cook fenestrated device with the modified preloaded delivery system (MPDS) with a biport handle and preloaded catheters. Methods: A multicenter retrospective single arm cohort study was performed, including all consecutive patients with complex abdominal aortic aneurysm repair an
Objectives: The aim of this study was to investigate genetic outcomes, analyze the family experience, and describe the process of implementing genetic sequencing for children with profound sensorineural hearing loss (SNHL) at a tertial audiological center in southern Sweden. Design: This is a prospective pilot study including eleven children with profound bilateral SNHL who underwent cochlear impl
Background: In sub-Saharan Africa, truckers and female sex workers (FSWs) have high HIV risk and face challenges accessing HIV testing. Adding HIV self-testing (HIVST) to standard of care (SOC) programs increases testing rates. However, the underlying mechanisms are not fully understood. HIVST may decrease barriers (inconvenient clinic hours, confidentiality concerns) and thus we would expect a gr
Background: The purpose was to evaluate glial fibrillary acidic protein (GFAP) and total-tau in plasma as predictors of poor neurological outcome after out-of-hospital (OHCA) and in-hospital cardiac arrest (IHCA), including comparisons with neurofilament light (NFL) and neuron-specific enolase (NSE). Methods: Retrospective multicentre observational study of patients admitted to an intensive care u
Schema för GEOP04 Miljögeologisk markundersökning, 15 hp VT2 2016 Kursansvariga: Håkan Rosqvist hakan.rosqvist@tyrens.se, Per Sandgren per.sandgren@geol.lu.se Lärare från geologiska institutionen: PS = Per Sandgren, professor BS = Britta Smångs, bibliotekarie, geobiblioteket CS = Charlotte Sparrenbom, universitetslektor DH = Dan Hammarlund, professor Externa lärare: SA = Stefan Andersson, miljöför
https://www.geologi.lu.se/sites/geologi.lu.se/files/geop04_schema_2016-05-15.pdf - 2026-07-09
cosm02 literature list 2025 COSM02 Literature List Total Pages: 626 Not all students will read all the pages, one seminar has many readings where the readings are divided up. Allison, Anne. (2013). Introduction: Pain of Life, in . Precarious Japan, Durham NC: Duke University Press, pp. 1-20 > Pages to read for students: 20 > LUB: Available online from library > Added for new section of course Ames
https://www.ace.lu.se/sites/ace.lu.se/files/2025-06/cosm02%20literature%20list%202025.pdf - 2026-07-09
Brevmall 4 [MALL] Uppdragsbeskrivning – Föreståndare brandfarlig vara [Kursiv text i dokumentet är hjälptext för att använda mallen.] Allmän beskrivning Enligt 9 § i LBE ska den som bedriver tillståndspliktig verksamhet (tillståndshavaren) utse en eller flera föreståndare för verksamheten. Föreståndarens uppgift är att se till att verksamheten bedrivs enligt aktsamhetskrav (6§ LBE) och övriga skyl
Background: Combination lipid-lowering therapy (LLT) after myocardial infarction (MI) achieves lower low-density lipoprotein cholesterol (LDL-C) levels and better cardiovascular outcomes vs statin monotherapy. As a result, global guidelines recommend lower LDL-C but, paradoxically, advise treatment through a stepwise approach. Yet the need for combination therapy is inevitable as <20% of patients
Background: The routine use of sedation and analgesia during post-cardiac arrest care and its association with clinical outcomes remain unclear. This study aimed to describe the use of sedatives and analgesics in post-cardiac arrest care, and evaluate associations with good functional outcome, survival, clinical seizures, and late awakening. Methods: This was a post hoc analysis of the TTM2-trial,
