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Interfirm self-regulation through trade associations is common but its effectiveness is debated and likely varies by time, country, and industry. This study examines self-regulation of pharmaceutical marketing, characterized by delegation of major regulatory responsibilities to trade associations' self-regulatory bodies. In addressing critical research gaps, this study first analyzes 1,776 complai

Positioning with 5G signals generally requires connection to several base stations (BSs), which makes positioning more demanding in terms of infrastructure than communications. To address this issue, there have been several theoretical studies on single BS positioning, leveraging high-resolution angle and delay estimation and multipath exploitation possibilities at mmWave frequencies. This paper p

The inherently weak chiroptical responses of natural materials limit their usage for controlling and enhancing chiral light-matter interactions. Recently, several nanostructures with subwavelength scale dimensions were demonstrated, mainly due to the advent of nanofabrication technologies, as a potential alternative to efficiently enhance chirality. However, the intrinsic lossy nature of metals an

Little is known about the fate and uptake of nanoplastics (NPs) in natural ecosystems, mainly due to analytical limitations in measuring NPs in complex environmental matrices. Our aim was to quantitatively assess the transport, fate and biological uptake of NPs in freshwater ecosystems by using replicated wetland mesocosms and gold-doped polystyrene nanoparticles. We showed that 97% of the NPs wer

Background: Selective water uptake by neurons and glial cells and subsequent brain tissue oedema are key pathophysiological processes of hypoxic-ischemic encephalopathy (HIE) after cardiac arrest (CA). Although brain computed tomography (CT) is widely used to assess the severity of HIE, changes of brain radiodensity over time have not been investigated. These could be used to quantify regional bra

There has been widespread debate about whether the way in which we measure economic activity is fit for purpose in the twenty-first century. One aspect of this debate is to move away from measuring a nation's income (GDP) towards monitoring a nation's assets (their inclusive wealth), as a better indicator of sustainable economic development. We provide the first critical comparison of the approach

Climate change poses an existential threat to humanity. It is now indisputable that the primary cause of this threat is human activity resulting in high greenhouse gas (GHG) emissions, which began during the Industrial Revolution and have continued to rapidly accelerate. The first warnings of impending and irreversible climate change were sounded decades ago, when governmental and intergovernmenta

A finite group with a Beauville structure gives rise to a certain compact complex surface called a Beauville surface. Gül and Uria-Albizuri showed that quotients of the periodic Grigorchuk–Gupta–Sidki (GGS-)groups that act on the p-adic tree, for p an odd prime, admit Beauville structures. We extend their result by showing that quotients of infinite periodic GGS-groups acting on pn-adic trees, for

Objectives To study informed consent to midwifery practices and interventions during the second stage of labor and to investigate the association between informed consent and experiences of these practices and interventions and women's experiences of the second stage of labor. Methods This study uses an observational design with data from a follow-up questionnaire sent to women one month after giv

The stimulator of interferon genes (STING) plays a significant role in immune defense and protection against tumor proliferation. Many cyclic dinucleotide (CDN) analogues have been reported to regulate its activity, but the dynamic process involved when the ligands activate STING remains unclear. In this work, all-atom molecular dynamics simulations were performed to explore the binding mode betwe

Climate may regulate dissolved organic carbon (DOC) composition across the peat-water interface, but experimental evidence is scarce. We manipulated the climate in peatland and recipient surface water mesocosms to reflect four different climate warming scenarios. In half of the mesocosms, the water level was managed to avoid drought, after which responses were recorded during two annual cycles. It

We continue our work on the light-front formulation of quarkonium γ∗γ transition form factors, extending the formalism to JPC = 2++ tensor meson states. We present an analysis of γ∗γ → χc2 transition amplitude and the pertinent helicity form factors. Our relativistic formalism is based on the light-front quark-antiquark wave function of the quarkonium. We calculate the two-photon decay width as we

We present the first data release of VELOcities of CEpheids (VELOCE), dedicated to measuring the high-precision radial velocities (RVs) of Galactic classical Cepheids (henceforth, Cepheids). The first data release (VELOCE DR1) comprises 18 225 RV measurements of 258 bona fide classical Cepheids on both hemispheres collected mainly between 2010 and 2022, along with 1161 observations of 164 stars, m

Introduction: Lichen planus is a relatively common inflammatory condition of the nails, skin, and mucosal surfaces. Oesophageal involvement of lichen planus is thought to be very rare, mainly described in case reports, but is associated with a high risk of oesophageal stenosis as well as squamous cell carcinoma. No evidence-based treatment recommendations exist, with the majority of described trea

In recent years there has been a renewed interest in the basal forebrain cholinergic system as a target for the treatment of cognitive impairments in patients with Parkinson's disease, due in part to the need to explore novel approaches to treat the cognitive symptoms of the disease and in part to the development of more refined imaging tools that have made it possible to monitor the progressive c

Cortical arealization arises during neurodevelopment from the confluence of molecular gradients representing patterned expression of morphogens and transcription factors. However, whether similar gradients are maintained in the adult brain remains unknown. Here, we uncover three axes of topographic variation in gene expression in the adult human brain that specifically capture previously identifie

BACKGROUND: Lung transplantation is hindered by low donor lung utilization rates. Infectious complications are reasons to decline donor grafts due to fear of post-transplant primary graft dysfunction. Mesenchymal stem cells are a promising therapy currently investigated in treating lung injury. Full-term amniotic fluid-derived lung-specific mesenchymal stem cell treatment may regenerate damaged lu

This study aims to determine the optimal pressure for the accumulator tank in a wave energy converter (WEC) with hydraulic power take-off (PTO) to maximize energy generation. A simulation-based approach was employed to analyze the buoy's performance with wave data generated from the Wafo toolbox using the generalized Pierson–Moskowitz (GPM) spectrum. These data were then fed into a Simulink model

Hydrological models are generally calibrated and validated using a suite of well-known statistical metrics, which sometimes lack clear connection and tailoring to the local users’ need and therefore limits the evaluation, especially in the case of global climate services. Therefore, in this study, two types of application-based evaluation metrics are introduced, addressing (i) temporal matching of