Szabadgyokok es reaktiv nitrogen speciesek szerepe a diabetes kesoi szovodmenyeinek kialakulasaban patkanyban
In this time-course study the levels of different reactive species, especially those of nitric oxide and peroxynitrite were determined in streptozotocin-induced diabetic rat tissues at different time-points after the onset of the disease, before the development of histopathological damages. Significantly higher steady state free radical concentrations were found in the liver 3 weeks after the onse