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Vacuolar Ca2+-ATPases in Plants. Regulation by calmodulin binding to a N-terminal autoinhibitory domain.

Popular Abstract in Swedish Kalcium är ett livsviktigt ämne för både djur och växter. Kalcium behövs t.ex. för uppbyggnaden av skelettet, för att hjärtat skall slå och för att musklerna skall dras samman. I växter är kalcium en viktig beståndsdel i cellväggarna och behövs också vid bl.a. celldelning. Trots detta måste koncentrationen av fria kalciumjoner inne i cellen (i cellvätskan) hållas mycketThe calcium ion (Ca2+) is essential for all plant and animal life. One important function of Ca2+ is as a second messenger in the responses of the cell to environmental and hormonal signals as well as in some intrinsic developmental processes. The intracellular concentration of Ca2+ must be strictly regulated, since a high concentration of free cytosolic Ca2+ is toxic. All eukaryotic cells carry c

Pharmacokinetic and pharmacodynamic studies on cisplatin in mice and men

Methodological tools for studies of the cytostatic agen cisplatin (CDDP) were explored and applied to elucidate various aspects of pharmacokinetics, drug distribution, chemomodulation and pharmacodynamics. An immunohistochemical assay for analysis of CDDP-DNA adducts, i.e. the drug in its probable target position, was modified to allow quantitation with computerized image analysis. The methodologi

Nitric Oxide Synthase in Pancreatic Islets During Trauma and Parenteral Feeding

Popular Abstract in Swedish Den första beskrivningen av diabetes mellitus gjordes redan 1500 före Kristus när en faraos läkare noterade att myror samlade sig omkring urin från vissa människor men inte andras. På 1700-talet beskrevs för första gången närvaron av större mängder socker i såväl blod som urin hos diabetiska patienter. På 1920-talet upptäcktes insulin i bukspottkörteln (pancreas) och saThe influence of trauma (acute pancreatitis) or total parenteral nutrition (TPN) on pancreatic islet hormone secretion in relation to islet expression of inducible nitric oxide synthase (iNOS) was investigated. Acute pancreatitis resulted in an impaired glucose-stimulated insulin secretion (GSIS) which was found to be parallelled by a marked expression of iNOS and an exaggerated NO production in t

Gunnar Rosendal i kyrkopolitiken : Europeiska perspektiv på kyrklig förnyelse

This article deals with Gunnar Rosendal within church politics in a European perspective. The term church politics is here used in a broad sense, referring to the church’s management of internal problems and conflicts as well as the political strategies of the church in its relation to state and society. In my study I focus on three fields that in various ways got church political consequences or This article deals with Gunnar Rosendal within church politics in a European perspective. The term church politics is here used in a broad sense, referring to the church’s management of internal problems and conflicts as well as the political strategies of the church in its relation to state and society. In my study I focus on three fields that in various ways got church political consequences o