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Several chemotherapeutic drugs are now considered to exert anti-tumour effects, by inducing an immune-promoting inflammatory response. Cisplatin is a potent chemotherapeutic agent used in standard medulloblastoma but not glioblastoma protocols. There is no clear explanation for the differences in clinical efficacy of cisplatin between medulloblastomas and glioblastomas, despite the fact that cisp

Hyperdiploidy, i.e. gain of whole chromosomes, is one of the most common genetic features of childhood acute lymphoblastic leukemia (ALL), but its pathogenetic impact is poorly understood. Here, we report a proteogenomic analysis on matched datasets from genomic profiling, RNA-sequencing, and mass spectrometry-based analysis of >8,000 genes and proteins as well as Hi-C of primary patient samples f

Traditionally, diesel engine control has had to rely on indirect feedback variables and empirical open-loop maps because direct measurements of the variables representing high-level objectives, such as emissions, have not been available in production engines. With new sensors being developed, the opportunity opens to design the controller directly based on high-level objectives. In this paper, we

This paper describes how high-speed computer vision can be used in a motion control application. The specific application investigated is a dart catching robot. Computer vision is used to detect a flying dart and a filtering algorithm predicts its future trajectory. This will give data to a robot controller allowing it to catch the dart. The performance of the implemented components indicates that

Solid waste collection and hauling account for the greater part of the total cost in modern solid waste management systems. In a recent initiative, 3,300 Swedish recycling containers have been fitted with level sensors and wireless communication equipment thereby giving waste collection operators access to real-time information on the status of each container. In a previous study (Johansson, 2006)

Här redogörs för de senaste besluten inom Bird- Life Sveriges Taxonomikommitté (Tk) som togs på ett möte i december 2018 på Getterön. Detta är en förkortad version, den fullständiga – ”Rapport 10” – finns att ladda ner på birdlife.se/Tk. Tk:s Västpalearktislista har uppdaterats med samtliga ändringar.Här redogörs för de senaste besluten inom Bird- Life Sveriges Taxonomikommitté (Tk). vilka togs på ett möte i december 2018 på Getterön. Detta är den fullständiga rapporten, inkluderande referenser. En kortare version finns i Vår Fågelvärld nummer 2/2019. Tk:s Västpalearktislista har uppdaterats med samtliga förändringar och heter nu VP5. Likaså har Namnlistan över svenska fågel

Veterligen sympatiserade inga svenska nationalekonomer med Hitlers Tredjerike. I denna artikel riktas inte desto mindre uppmärksamhet mot en av de mestframträdande ekonomerna, Gustav Cassel. Detta mot bakgrund av att hanunder mellankrigstiden, fram till Hitlers maktövertagande 1933, var mycketengagerad i och för Tyskland. Hur hanterade han den tyska genomklappningen?I Cassels memoarer framstår Naz

This paper presents and discusses how to support disciplinary communities of academic teachersto create a lasting change in educational culture. By stressing the similarities with the fully accepted research culture and their research knowledge this have been possible. Evaluations consistentlyshow that participants appreciate the collegial approach. It offers them an opportunity to deal withchalle

In this paper, we have analyzed a nationwide debate following the introduction of an individual meritsystem for educational development. When reforms are aimed towards research, even the toughestdiscussions can most often be resolved when arguments are backed by evidence. Not surprisingly, as this goes hand in hand with the language and mindset of the receivers in the researchcommunity. But, when

The role of raw plantain flour (RPF) and its citric acid (CA)-esterified counterpart (EPF) on the carbohydrate nutritional properties of cookies was investigated. Cookies were elaborated with commercial wheat flour (CWF), RPF, EPF, or a CWF-EPF blend, and assessed for composition, starch digestibility, texture and sensory properties. EPF-cookie showed the lowest digestible starch (DS) content and

The evolution of soot and coal/char as well as the flame properties, during pulverized coal combustion in O 2 /N 2 and O 2 /CO 2 conditions, were experimentally studied using optical diagnostics. The jet flames of pulverized coal particles were produced by using an entrained-flow reactor with optical access, and the oxygen concentrations of the gas carrying pulverized coal particles were vari

I den offentlege debatten om høgare utdanning er undervisarane påfallande fråverande. Dei sterkaste stemmene tilhøyrar politikarane, studentane, institusjonsleiarane og pedagogane. Når undervisarane melder seg på er det oftast i ein klagesong over høgt arbeidspress, krevjande studentar og mangel på tid og ressursar til forsking. Kvifor oppfattar brorparten av undervisarar i høgare utdanning undervI den offentlege debatten om høgare utdanning er undervisarane påfallande fråverande. Dei sterkaste stemmene tilhøyrar politikarane, studentane, institusjonsleiarane og pedagogane. Når undervisarane melder seg på er det oftast i ein klagesong over høgt arbeidspress, krevjande studentar og mangel på tid og ressursar til forsking. Kvifor oppfattar brorparten av undervisarar i høgare utdanning underv

Objectives: Measurement of lactate in fetal blood is used to assess the degree of anaerobic metabolism. The technical difficulties in obtaining enough scalp blood for analysis by a bloodgas-analyzer advocates for the use of a point-of-care device. StatStrip®Xpress™ (SSX) has shown promising properties but needs further evaluation before implementation into fetal surveillance. Methods: Arterial/ve