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For as long as there have been supply chains, there have been disruptions, and no supply chain, logistics system, or infrastructure network is immune to them. Nevertheless, supply-chain disruptions have only recently begun to receive significant attention from practitioners and researchers. Hence, different mitigation and contingency strategies have been addressed. But there is still an almost unt
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This thesis, which is based on four original papers, covers different aspects of antibody development. The overall goal of my work has been to obtain an increased understanding of antibody repertoires as they develop in vivo and in vitro. In Paper I-III antibody repertoires was evaluated and used to dissect virus-induced antibody responses and characterize such antibodies. Furthermore, tools for m
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We present a method for creating and validating a nonlinear controller by the composition of heterogeneous local control laws appropriate to different operating regions. Like fuzzy logic control, these methods apply even in the presence of incomplete knowledge of the structure of the system, the boundaries of the operating regions, or even the control action to take. Unlike fuzzy logic control, th
