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To investigate the consumption of alcohol among emergency room patients, we included 395 patients above 18 years old entering the emergency room during a period of ten days. The patients completed a questionnaire about alcohol consumption, smoking habits and medication. In our investigation 56% of the men and 25% of the women had a daily consumption above the limits recommended by the Ministry of
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The purpose of this study was to describe changes in smoking behaviour and exposure to passive smoking among hospital employees at a large Danish University Hospital (Bispebjerg Hospital) from 1992 until 1999 as part of a program toward a smoke-free hospital. The study was based upon three cross-sectional self-administered questionnaires surveys carried out among all employees at the hospital - ap
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Objectives: Smoking cessation programmes in which groups of smokers have the opportunity to learn behavioural techniques and benefit from mutual support for quitting are widely available. The aim of this review is to determine the effectiveness of smoking cessation programmes delivered in a group format, for helping smokers achieve long-term smoking cessation. Search strategy: TheTobacco Addicitio
Experts in election news coverage: Process or substance?
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Objectives:To assess the effectiveness of smoking cessation programs implemented during pregnancy and to assess the impact of these programs on the health of the fetus and infant, on the mother and on the family. Search strategy: Randomized and quasi-randomized controlled trials indentified by the search strategy of the Cochrane Pregnancy and Childbirth Group, supplemented by the search strategy o
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Observer variation in the assessment of the histopathologic diagnosis of acute appendicitis
Background: The objectives of this study were to determine observer variation in the assessment of the histopathologic diagnosis of acute appendicitis. Methods: Two consultant pathologists independently evaluated 415 appendectomy specimens (set I). After a consensus conference at which the observers unified the criteria of the diagnosis of acute appendicitis, another 396 appendectomy specimens (se
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The alcohol patient and surgery
Alcohol abusers have a threefold increased risk of post-operative morbidity after surgery. The most frequent complications are infections, cardiopulmonary insufficiency, and bleeding episodes. Pathogenesis is suppressed immune capacity, subclinical cardiac dysfunction, and haemostatic imbalance. The economic implications of alcohol abuse in surgical patients are tremendous. Interventional studies
Is carbohydrate deficient transferrin a useful marker of harmful alcohol intake among surgical patients?
Objective: To find out whether the biological marker, carbohydrate deficient transferrin (CDT), was helpful in the detection of alcoholic patients in a surgical unit. Design: Prospective open study. Setting: Teaching hospital, Denmark. Subjects: 286 men and 248 women admitted to the department of surgical gastroenterology between March and July 1996. Main outcome measures: Specific interview about
Association between alcoholism and diverticulitis
Preoperative alcoholism and postoperative morbidity
Background: Preoperative risk assessment has become part of daily clinical practice, but preoperative alcohol abuse has not received much attention. Methods: A Medline search was carried out to identify original papers published from 1967 to 1998. Relevant articles on postoperative morbidity in alcohol abusers were used to evaluate the evidence. Results: Prospective and retrospective studies demon
Stress response to endoscopy
Background: Upper gastrointestinal endoscopy is often accompanied by tachycardia, which may lead to myocardial ischaemia. The pathogenesis for tachycardia is unknown, but the classic endocrine stress response may be of importance. Methods: Seventeen patients (median age, 60 years) undergoing diagnostic gastroscopy without sedation or supplemental oxygen therapy were monitored by means of electroca
Effect of preoperative abstinence on poor postoperative outcome in alcohol misusers : Randomised controlled trial
Objective. To evaluate the influence of preoperative abstinence on postoperative outcome in alcohol misusers with no symptoms who were drinking the equivalent of at least 60 g ethanol/day. Design. Randomised controlled trial. Setting. Copenhagen, Denmark. Subjects. 42 alcoholic patients without liver disease admitted for elective colorectal surgery. Interventions. Withdrawal from alcohol consumpti
A Mouse Model for the Transition of Streptococcus pneumoniae from Colonizer to Pathogen upon Viral Co-Infection Recapitulates Age-Exacerbated Illness
Streptococcus pneumoniae (pneumococcus) is an asymptomatic colonizer of the nasopharynx in most individuals but can progress to a pulmonary and systemic pathogen upon influenza A virus (IAV) infection. Advanced age enhances host susceptibility to secondary pneumococcal pneumonia and is associated with worsened disease outcomes. The host factors driving those processes are not well defined, in part
Population based cohort study of the association between alcohol intake and cancer of the upper digestive tract
Objective: To examine the relation between different types of alcoholic drinks and upper digestive tract cancers (oropharyngeal and oesophageal). Design: Population based study with baseline assessment of intake of beer, wine, and spirits, smoking habits, educational level, and 2-19 years' follow up on risk of upper digestive tract cancer. Setting: Denmark. Subjects: 15,117 men and 13,063 women ag
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The present population based cohort study investigates the association between alcohol intake and cancer of the upper digestive tract. The design was prospective with baseline assessment of intake of beer, wine and spirits, smoking habits, educational level and 2-19 years' follow up on risk of upper digestive tract cancer (oropharyngeal and oesophageal). During a mean follow up of 13.5 years, 156