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Background: Uterine sarcomas are rare and high-quality evidence regarding optimal treatment is limited and difficult to produce. Methods: A total of 618 patients with uterine sarcoma were identified in the Swedish Quality Registry for Gynecologic Cancer (SQRGC) from 2010 to 2020. Survival was analyzed according to stage, histology and treatment modality. Results: The incidence of uterine sarcoma w
Obesity-related type 2 diabetes (T2D) is currently defined by insulin resistance and impaired insulin secretion. Sulfonylureas, thiazolinediones, and insulin are effective at lowering glycemia yet have not consistently translated into improved long-term outcomes. In contrast, recent interventions often produce metabolic benefits that exceed expectations based on glucose lowering alone. These contr
This article examines the role of private defence investment as part of the efforts to define the scope and meaning of EU social sustainability, at a time of increased EU investment interest in the aerospace and defence industry (A&D). One of the central questions posed by private investors, civil society and international legal scholars alike is, in fact, whether investment in the production
This paper investigates collaborative mobile edge computing (MEC) servers for large language model (LLM) inference under soft deadline constraints. In this system, to improve the quality of service, computations are expected to be completed within their deadlines. However, due to dependencies among tasks or subtasks, any missed deadline can lead to catastrophic consequences for the entire request.
In this thesis machine learning applications to modern particle accelerators are developed and tested at a number of facilities. The focus is on improving and advancing longitudinal diagnostics, with a major project focusing on non-destructive predictions of beam distributions in longitudinal phase space. Applications are developed using data collected from MAX IV, FERMI, SwissFEL and FLASH. Beyon
ABSTRACT The efficacy of cryosurgery for skin cancers is believed to depend on thaw time, which may be influenced by the presence of adrenaline in local anaesthetics due to its vasoconstrictive effects. This is the first study to perform detailed, non-invasive temperature measurements using infrared (IR) thermography during cryosurgery for basal cell carcinomas (BCCs), evaluating the impact of adr
Africa's historical borderlands are persistently associated with low levels of economic development. This paper examines how these regions respond to development interventions, analysing whether the long-run development advantage associated with colonial Christian missions persists near historical homeland borders. Combining georeferenced data on 3,365 pioneering mission stations with high-resolut
BACKGROUND: Current diagnostic criteria for postural orthostatic tachycardia syndrome (POTS) require history of orthostatic intolerance and heart rate elevation of ≥30 bpm in adults or ≥40 bpm in adolescents during a 10-minute standing or a tilt table test. Many patients with orthostatic intolerance experience autonomic dysfunction and functional impairment despite not meeting the required heart r
Despite the prevalence of slavery in world history, our understanding of its persistence remains limited. Most previous studies focus primarily on slavery as a labour contract, indistinguishable from other coercive arrangements such as serfdom. More recent literature on slavery in the United States shows that enslaved people also played an important role as financial instruments. In this article,
The economic history of British colonialism in Southern Africa is defined by three interrelated dynamics: the initial expansion driven by chartered companies, a substantial influx of European settlers, and the establishment of racially segregated, unequal Neo-European societies. In this chapter, we show how the discovery of minerals in the nineteenth century radically reshaped the economic and soc
Understanding the determinants that influence parents’ decisions to participate with their infants in primary prevention trials is essential for achieving representative study samples and ensuring the generalizability of outcomes. We analyzed quantitative and qualitative data collected from infants eligible for the Primary Oral Insulin Trial (N= 2,750) or the Supplementation with B. INfantis for M
The Sloan Digital Sky Survey-V (SDSS-V) Magellanic Genesis Survey is a spectroscopic program designed to map the kinematic and chemical structure of the Magellanic Clouds (MCs) using APOGEE and BOSS spectroscopy. This overview describes the survey’s design, target selection, and science goals and highlights some first results using these data. In the inner regions of the Large and Small Magellanic
Protest and activism are endemic and potent features of many nations’ political life and critical potential counters to democratic backsliding and authoritarianism. In this review article, we meta-analytically examine six decades of research findings on what explains participation, focusing particularly on two well-studied protest forms: marches and demonstrations. Focusing on these iconic and com
Surface-enhanced Raman scattering (SERS) has emerged as a powerful technique for the rapid and sensitive detection of pesticide residues, particularly targeted pesticides of concern in food safety. However, hotspot intensification strategies in hydrogel-based SERS substrates that rely on solvent-exchange-induced shrinkage often suffer from concomitant analyte loss, thereby limiting detection relia
Wild edible fruits are underexplored sources of nutrients and bioactives. This study assessed the bioactive profileand in vitro functional properties of four Mozambican wild fruits: Adansonia digitata (AD), Dialium schlechteri (DS),Garcinia livingstonei (GL), and Syzygium cordatum (SC). Phenolic compounds (PCs), dietary fibers (DF), minerals,and sugars were analyzed along with phenolic bioaccessibWild edible fruits are underexplored sources of nutrients and bioactives. This study assessed the bioactive profile and in vitro functional properties of four Mozambican wild fruits: Adansonia digitata (AD), Dialium schlechteri (DS), Garcinia livingstonei (GL), and Syzygium cordatum (SC). Phenolic compounds (PCs), dietary fibers (DF), minerals, and sugars were analyzed along with phenolic bioacc
This thesis comprises three papers in the field of proof complexity, in which the objects of study are certificates of unsatisfiability. In algebraic proof complexity, the aim is to prove lower bounds on the complexity of certifying that there is no common root of a given set of polynomials. We will be especially concerned with the polynomial calculus proof system, where this is accomplished by it
The starting point of this dissertation is the increasing number of Swedish consumers who use the Internet for shopping. Convenience is said to be an important ground for this choice. However, there are few studies that attempt to understand the true meaning of convenience. This study sets out to understand what convenience entails for Internet shoppers, what characterizes a convenient Internet sh
