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COVID-19 convalescent plasma for B-cell depleted patients : a systematic review and individual patient data meta-analysis

COVID-19 convalescent plasma (CCP) obtained from recently recovered people is safe and effective against SARS-CoV-2. Currently available CCP is a “hybrid” product with antibodies from individuals who had both infection and vaccination (vaccine-boosted CCP). B-cell depleted patients are at risk of not producing antibodies after either infection or vaccination, hence conceivably among those who woul

Unveiling low-dimensional patterns induced by convex non-differentiable regularizers

This paper explores the asymptotic distributions of low-dimensional patterns in linear regression with regularizers such as Lasso, Elastic Net, Generalized Lasso, and SLOPE, as the number of observations n grows and the penalty increases at rate n. While the asymptotic distribution of rescaled estimation errors is well-understood, convergence of patterns lacks proof in the literature, even for Las

State gender and ontological dislocation : Gendering Iran's revolutionary identity and nuclear behaviour

What happens when states' gender identity is endangered? How may a state actor's gender identity be conceived of and (de)stabilised in the first place? What are the ontological effects of such disruptions? And how do states respond to ruptures in their gender identities or selves? Despite growing attention to gendered narratives in ontological security studies (OSS), the extant scholarship has eng

The Lived Experience of the Trusting Nurse–Patient Relationship Among Patients Admitted to Internal Medicine Wards

Aim: To explore the lived experience of the trusting nurse–patient relationship among patients admitted to internal medicine wards. Design: A qualitative study guided by van Manen's hermeneutic phenomenological approach. Methods: Semi-structured interviews were conducted with fourteen hospitalised patients in a Danish University hospital in 2024. Data were analysed through thematic reflection. Res

Tumour-infiltrating immune cells in tonsillar cancer : no tissue-level signs of inflammageing in the elderly

Background: Age-related immunosenescence, also known as ‘inflammageing’, may impact the elderly’s ability to mount immune responses against cancers and compromise the effectiveness of immune checkpoint inhibition (ICI). In this context, data on tonsillar cancer (TC), a subset of head and neck squamous cell cancer (HNSCC), are lacking. Aims/objectives: To compare the presence/distribution and featu

The challenges and opportunities of membrane processes in the protein shift

Membrane technology has revolutionized protein recovery in the food industry, beginning with whey protein extraction via ultrafiltration. This success led to its application in concentrating animal proteins like blood plasma, fish proteins, and albumen. As the protein shift towards plant-based sources grows, membrane processes now enable the industrial recovery of wheat, sunflower, and rapeseed pr

An analytical–numerical approach for the stability analysis of large strain thermo-elastoplastic material models

The paper deals with the notion of stability for thermo-elastoplastic materials undergoing large strains. The stability analysis is performed by using the perturbation approach applied to a comprehensive material model derived in a thermodynamic format. As the main contribution of this paper a stability condition for a material model incorporating geometrical and material non-linearities under ful

Modalities of Bureaucratic Violence : Bordering via Civil Documentation in Myanmar

This article examines bordering via bureaucratic violence in Myanmar in relation to civil documentation. We categorize bureaucratic encounters into five modalities of bureaucratic violence: deferred citizenship and higher evidentiary burdens; negative discretion in administrative decision-making; denationalization; administrative erasure; and movement restrictions. Since the 2021 military coup, su

Nutritional effects on the expression of cryptic pigmentation in freshwater isopods

Cryptic pigmentation is a key phenotypic adaptation that helps many benthic invertebrates evade visual predators. However, little is known about whether and how the expression of pigmentation phenotypes that match the habitat background is influenced by the availability of nutritional resources. Here we investigated whether variation in both the background and the nutritive composition of benthic

Manipulating Thermoacoustic Streaming : Measuring the Synergy of Laser-induced Temperature Gradients and Ultrasonic Pressure Fields in Acoustofluidic Microchannels

In Acoustofluidics, sound pressure waves can cause a force field on the liquid in a microfluidic channel. The forces depend on density and compressibility of the medium as well as the pressure and velocity amplitude of the sound. The forces lead to a steady flow in the bulk of the fluid, namely acoustic streaming. If a localized change in temperature introduces a gradient in compressibility and de

Flame soot characterization using combined multi-wavelength thermo-optical analysis and Raman spectroscopy

Multi-wavelength thermo-optical analysis (MW-TOA) and Raman spectroscopy are commonly used methods to study soot sampled on filters, in terms of carbon content, nanostructure, and absorption properties. In this work, these techniques were combined to study how these characteristic properties of soot change in premixed flames, 1) at various flame heights during soot maturation and 2) as a result of

Movement texts : materiality, social practice, and discursive genre

This article aims to conceptualize movement texts as a crucial yet often overlooked phenomenon in the articulation of collective identity and narratives in the context of social movements. We define movement texts as symbolic acts that publicly manifest a social movement as a collective actor. Against the backdrop of the “narrative turn” in social movement studies and adjacent fields, we argue tha

Cognitive mechanisms in simile and metaphor comprehension

This study investigates whether metaphors and similes are processed the same way or not. Comparison accounts of metaphor claim that metaphors and similes use the same cognitive mechanisms because metaphors are implicit similes, while Categorization accounts claim that the two figures of speech require different cognitive mechanisms. It is unclear which position has the most support. We address thi

The fibroblast epigenome underlies SS18::SSX-mediated transformation in synovial sarcoma

Synovial sarcoma (SyS) is an aggressive soft-tissue malignancy that is characterised by a pathognomonic t(X;18)(p11.2;q11.2) translocation, which produces the fusion oncogene named SS18::SSX. Despite recent advancements in our understanding of synovial sarcoma biology, the cell-of-origin remains undefined. A mesenchymal stromal cell (MSC) specific CreERT2 line was employed to express SS18::SSX in

Advances in the clinical management of parathyroid disorders : report from the 2024 workshop by the ESE educational program on parathyroid disorders

The present report from the ESE Educational Program on Parathyroid Disorders (PARAT Program) presents recent developments and novelties in the clinical care of parathyroid disorders in a question-and-answer format, based on a satellite workshop held in relation to the European Congress of Endocrinology in Stockholm, May 2024. The workshop focused on clinical aspects of 3 main themes: primary hyper

Pathological response to pembrolizumab-based neoadjuvant therapy in ER-low vs. ER-zero breast cancer : a Swedish population-based cohort study

Background: Emerging evidence indicates that estrogen receptor-low (ER-low)/human epidermal growth factor receptor 2 negative (HER2-) breast cancer (BC) may more closely resemble ER-negative (ER-zero, < 1%) rather than ER-positive disease in terms of biological and clinicopathological characteristics. In Sweden, ER-low (ER 1–9%) BC is managed as triple-negative breast cancer (TNBC) and is thus eli

Locus coeruleus-entorhinal cortex tract integrity is linked to plasma tau and glial fibrillary acidic protein

INTRODUCTION: Pretangle tau inclusions from the locus coeruleus (LC) are hypothesized to propagate to the entorhinal cortex (EC) via neuron-to-neuron transmission along its projections. The lower integrity of the LC-EC pathway accompanying Alzheimer's disease (AD) pathology is supported by post mortem studies, but in vivo evidence remains limited. METHODS: We associated diffusion-weighted 7T magne

Microbial associations and viruses on the risk of celiac disease (MAVRiC) : a longitudinal post-hoc case-cohort study

Celiac disease etiopathogenesis requires genetic predisposition and exposure to gluten, yet these factors alone are not sufficient. Larger longitudinal studies are needed to determine the role of time-varying infections and gut microorganisms. The aim was to design a celiac disease case-cohort longitudinal study using The Environmental Determinants of Diabetes in the Young (TEDDY) study. By age 3-