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Muco-epidermoid tumour of the bronchus

A 7-year-old boy with recurrent pneumonia of the right lower lobe is described. At bronchoscopy a small tumour almost totally obliterating the right lower lobe was detected. Surgical treatment was undertaken. Histopathologic studies showed findings consistent with those of a muco-epidermoid tumour. The case emphasizes bronchoscopy as an important investigation in children with recurrent pneumonia.

Endometrial cancer risk prediction including serum-based biomarkers : results from the EPIC cohort

Endometrial cancer risk prediction models including lifestyle, anthropometric and reproductive factors have limited discrimination. Adding biomarker data to these models may improve predictive capacity; to our knowledge, this has not been investigated for endometrial cancer. Using a nested case–control study within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort, we

Intra-tumour IgA1 is common in cancer and is correlated with poor prognosis in bladder cancer.

A high frequency of IgA1-positive tumour cells was found in tissue micro-arrays of oesophagus, colon, testis, lung, breast, bladder and ovarian cancer. IgA1 was observed in the cytoplasm and the plasma membrane. A correlation was found between intra-tumour IgA1 and poor overall survival in a large cohort of bladder cancer patients (n = 99, p = 0.011, log-rank test). The number of IgA1-positive tum

Obesity/insulin resistance rather than liver fat increases coagulation factor activities and expression in humans

Increased liver fat may be caused by insulin resistance and adipose tissue inflammation or by the common I148M variant in PNPLA3 at rs738409, which lacks both of these features. We hypothesised that obesity/insulin resistance rather than liver fat increases circulating coagulation factor activities. We measured plasma prothrombin time (PT, Owren method), activated partial thromboplastin time (APTT

Carrier testing and prenatal diagnosis of haemophilia - utilisation and psychological consequences

Attitudes towards prenatal diagnosis, and abortion vary widely between different countries, religions, cultures and over time. Carrier testing and prenatal diagnosis (PD) of haemophilia have become an integrated part of the comprehensive care for haemophilia in Sweden as well as in many other countries. Almost all carriers are interested in carrier testing if they are aware of the possibility. Wit

Characterization of resident lymphocytes in human pancreatic islets

The current view of type 1 diabetes (T1D) is that it is an immune-mediated disease where lymphocytes infiltrate the pancreatic islets, promote killing of beta cells and cause overt diabetes. Although tissue resident immune cells have been demonstrated in several organs, the composition of lymphocytes in human healthy pancreatic islets have been scarcely studied. Here we aimed to investigate the ph

Wind tunnel as a tool in bird migration research

Wind tunnels, in which birds fly against an artificially generated air flow, have since long been used to evaluate aerodynamic properties of steady bird flight. A new generation of wind tunnels has also allowed the many processes associated with migratory flights to be studied in captivity. We review how wind tunnel studies of aerodynamics and migratory performance together have helped advancing o

The importance of genetic factors for the development of arthropathy : A longitudinal study of children and adolescents with haemophilia A

Haemophilia A is a congenital bleeding disorder characterised by recurrent haemorrhages into the major joints. Haemophilic arthropathy is a well-established outcome of recurrent joint bleeding; however, it is clear that multiple factors determine the extent and severity of its occurrence. We sought to identify genetic factors related to abnormalities in range of motion (ROM) in the knees, ankles a

Understanding medical aspects of violent crimes in Sweden’s region Skåne: a retrospective cross-sectional design of the ViCS project

Introduction: While there has been a reduction in specific homicide categories in Sweden, the last decade has witnessed an increase in the overall rate. The escalation is predominantly linked to heightened gun violence associated with criminal gangs. As a result, Sweden faces an extreme rate of shootings and firearm-related homicides, constituting one of the most severe instances across Europe. Ho

Guest editorial: Accounting and performance measurement in the age of rankings, quality assurance, accreditation, and excellence frameworks

Over the past three decades, numbers, particularly those that can be expressed in financial terms, have come to be presented as a form of truth. Today, numbers guide and govern us, and shape and influence who we are, or who we should try to become (Kurunmäki et al., 2016). A few decades ago, this quantifying movement was restricted to a few fields. Today, however, it appears as if no one can escap

Peacocks, penknives and power : On the implications of evolutionary psychology for strategic communication

This article conceptualizes evolutionary theory as a bridge between existing theorizing in strategic communication on the one hand, the mind sciences on the other. It discusses six core concepts of evolutionary psychology that have a bearing on strategic communication theory: a) the human as a highly flexible social species; b) the regulation of individually-minded vs. collectively-minded behavior

Mixing in ice covered lakes

Mixing in ice covered lakes is caused by through-flow currents, oscillations of the ice cover and by convective currents induced by heat flow from the sediments or by solar radiation penetrating the ice. Mainly from studies in Swedish lakes, current velocities and mixing coefficients are quantified for the different processes generating water movement. Seiche movement caused by wind induced oscill