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Sociodemographic Factors’ Influence on the Consumption and Assessment of COVID-19 Related Information –An International Web-Based Survey

Information flows can affect people’s apprehension of the pandemic and related behaviors. The aim is to explore how people access and assess COVID-19 information and whether sociodemographic factors are associated with these processes. Quantitative data from 928 persons from 29 countries who participated in an international web-based survey was analyzed with descriptive and analytic statistics. TeInformation flows can affect people’s apprehension of the pandemic and related behaviors. The aim is to explore how people access and assess COVID-19 information and whether sociodemographic factors are associated with these processes. Quantitative data from 928 persons from 29 countries who participated in an international web-based survey was analyzed with descriptive and analytic statistics. Te

Cancer risks associated with germline PALB2 pathogenic variants : An international study of 524 families

PURPOSE To estimate age-specific relative and absolute cancer risks of breast cancer and to estimate risks of ovarian, pancreatic, male breast, prostate, and colorectal cancers associated with germline PALB2 pathogenic variants (PVs) because these risks have not been extensively characterized. METHODS We analyzed data from 524 families with PALB2 PVs from 21 countries. Complex segregation analysis

Breaking up and a new beginning when one’s partner goes into a nursing home : An interview study

In aging societies worldwide, spouses take on great responsibility for care when their partner continues to live at home. Nursing home placement occurs when the partner becomes too frail due to multimorbidity, and this will cause a change in the spouse’s life. This study aimed to explore the spouse’s experience of their partner’s move to a nursing home. Two interviews were conducted at 9-month int

‘The Little Engine That Could’: A Qualitative Study of Medical Service Access and Effectiveness among Adolescent Athletics Athletes Competing at the Highest International Level

Little is known about provision of medical services to adolescents prior to participating in international top-level sports. This study aimed to investigate experiences of medical service provision among high-level adolescent athletics (track and field) athletes from three continents. A thematic narrative analysis was applied to data collected from 14 athletes by semi-structured interviews. Althou

Treatment of ARS deficiencies with specific amino acids

Purpose: Recessive cytosolic aminoacyl-tRNA synthetase (ARS) deficiencies are severe multiorgan diseases, with limited treatment options. By loading transfer RNAs (tRNAs) with their cognate amino acids, ARS are essential for protein translation. However, it remains unknown why ARS deficiencies lead to specific symptoms, especially early life and during infections. We set out to increase pathophysi

Societal Transformations in Models for Energy and Climate Policy : The Ambitious Next Step

Whether and how long-term energy and climate targets can be reached depend on a range of interlinked factors: technology, economy, environment, policy, and society at large. Integrated assessment models of climate change or energy-system models have limited representations of societal transformations, such as behavior of various actors, transformation dynamics in time, and heterogeneity across and

Fighting Insurgency, Ruining the Environment : the Case of Forest Fires in the Dersim Province of Turkey

Environmental destruction has long been used as a military strategy in times of conflict. A long-term example of environmental destruction in a conflict zone can be found in Dersim/Tunceli province, located in Eastern Turkey. In the last century, at least two military operations negatively impacted Dersim’s population and environment: 1937–38 and 1993–94. Both conflict and environmental destructio

Vaccines and allergic reactions : The past, the current COVID-19 pandemic, and future perspectives

Vaccines are essential public health tools with a favorable safety profile and prophylactic effectiveness that have historically played significant roles in reducing infectious disease burden in populations, when the majority of individuals are vaccinated. The COVID-19 vaccines are expected to have similar positive impacts on health across the globe. While serious allergic reactions to vaccines ar

Statistical upscaling of ecosystem CO2 fluxes across the terrestrial tundra and boreal domain : Regional patterns and uncertainties

The regional variability in tundra and boreal carbon dioxide (CO2) fluxes can be high, complicating efforts to quantify sink-source patterns across the entire region. Statistical models are increasingly used to predict (i.e., upscale) CO2 fluxes across large spatial domains, but the reliability of different modeling techniques, each with different specifications and assumptions, has not been asses

Luminescence dating of holocene siliciclastic sediments in eastern Dahomey Basin, southwestern Nigeria

Several attempts at reconstructing geological settings and palaeoclimatic changes of the siliciclastic deposits of the Dahomey Basin, SW Nigeria, using relative age dating and correlation methods, have resulted in serious discrepancies on the ages. Therefore, a chronology framework established by an absolute age dating method is requisite to constrain the geological interpretation. This research f

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In this section of the European Resuscitation Council Guidelines 2021, key information on the epidemiology and outcome of in- and out-of-hospital cardiac arrest are presented. Key contributions from the European Registry of Cardiac Arrest (EuReCa) collaboration are highlighted. Recommendations are presented to enable health systems to develop registries as a platform for quality improvement and to

Decomposition analysis of per capita emissions : A tool for assessing consumption changes and technology changes within scenarios

Recent studies show that behaviour changes can provide an essential contribution to achieving the Paris climate targets. Existing climate change mitigation scenarios primarily focus on technological change and underrepresent the possible contribution of behaviour change. This paper presents and applies a methodology to decompose the factors contributing to changes in per capita emissions in scenar

Elevated temperatures increase growth and enhance foraging performances of a marine gastropod

The oceans continue to warm due to rising atmospheric greenhouse gas concentrations. Most climate-change studies of aquaculture species use temperature changes based on coarse-resolution climate models and without considering thermal ranges of an animal. Coarse-resolution climate models are generated by global-scale data, which is insufficient to capture the conditions of coastal areas where most

Secondary hyperparathyroidism, weight loss, and longer term mortality in haemodialysis patients : results from the DOPPS

Background: Wasting is a common complication of kidney failure that leads to weight loss and poor outcomes. Recent experimental data identified parathyroid hormone (PTH) as a driver of adipose tissue browning and wasting, but little is known about the relations among secondary hyperparathyroidism, weight loss, and risk of mortality in dialysis patients. Methods: We included 42,319 chronic in-centr

The management of women with ductal carcinoma in situ of the breast in Australia and New Zealand between 2007 and 2016

Background: The incidence of detected ductal carcinoma in situ (DCIS) continues to increase and now accounts for 14% of all breast cancer, and 20%–25% of screen-detected cases. Treatment trends of DCIS are important in order to inform the ongoing debate about possible overdiagnosis and overtreatment, but have not been investigated for over a decade in Australia and New Zealand. Against this backgr

Thermal performance in a pin fin-dimple/protrusion duct with different optimal objectives

In the present study, the optimal objective effect on the thermal performance of a rectangular duct with pin fins and dimples/protrusions is introduced. Four different optimal objectives are selected (entropy generation, entransy dissipation, enerty, and volume goodness factor). The baseline k-ù turbulence model is applied to solve the governing equations. The multi-island genetic algorithm (MIGA)