Filtyp
The concept of a mission-oriented innovation policy has been discussed for several years now, with definitions and conceptual understanding gradually emerging. Although focused on grand societal challenges, i.e. on a particular type of problem that has been receiving attention only in the last couple of years, the discussion and the design of mission-oriented innovation policy can still draw on pa
BACKGROUND: The heterogeneity of Alzheimer's disease (AD) and lack of well-validated markers of non-AD factors (e.g. TDP-43) present a substantial challenge for therapeutics. Our prior work showed discordance between tau (T) and neurodegeneration (N) identified non-AD factors in AD through multi-modality imaging. Here we tried a simplified approach using plasma ptau217 and medial temporal lobe (MT
Cardiac rehabilitation (CR) is a well established intervention for secondary prevention after myocardial infarction (MI), yet substantial variability in CR delivery and patient outcomes persists globally. This review provides an in-depth overview of the SWEDEHEART-CR registry, a comprehensive Swedish national quality registry that has facilitated continuous quality improvement and clinical researc
Purpose The EPHOR-NIGHT cohort was established to investigate how night shift work influences biological pathways and chronic disease risk using a comprehensive working-life exposome approach, focusing on cardiometabolic, mental health, cognitive and biological ageing outcomes. Participant The cohort includes 937 workers aged 20–65 years (88%female), primarily from the healthcare sector (96%) in S
The main objective of this work is to describe the design and testing of novel cam profiles, which are key for efficiency demonstration on a new class of internal combustion engine (ICE). A recuperated split cycle engine (RSCE) has unique demands for valve lift, duration and phasing when compared to a conventional 4-stroke. In particular, good control of the expander intake valve opening (IVO) app
Bend is a Naturum proposal located in Limhamn, Malmö, within a former limestone quarry. A Naturum is a Swedish visitor center designed to engage visitors with a site’s natural, cultural, and geological characteristics. In this project, Bend reinterprets the concept, translating the quarry’s qualities compression, fragility, and structural tension into architectural form. The design seeks to create
We describe an experimental setup for non-linear interaction and propagation of ultrashort and intense x-ray free-electron laser (XFEL) pulses in a dense gas. It allows one to provide high, but adjustable, target-gas pressures of up to 6 bar within a vacuum environment of 3∙10− 3 mbar or better. The setup enables investigation of intense x-ray propagation in an optically thick medium with minimal
Genetic variation in immune genes is an important component of genetic diversity. The genes in the major histocompatibility complex (MHC) provide an excellent model system for studying the mechanisms that generate and maintain genetic diversity in natural populations. While both demographic factors and pathogen-mediated selection processes contribute to the extreme diversity observed in the MHC sy
The spectrum of frontotemporal dementia/amyotrophic lateral sclerosis (FTD/ALS) and Huntington disease (HD) are fatal neurodegenerative disorders with no major disease-modifying therapies. Recent work has shown that the hallmark pathological proteins TAR DNA binding protein of 43 kDa (TDP-43) in FTD/ALS and mutant huntingtin (mHTT) in HD may be interlinked. Furthermore, these disorders share early
BACKGROUND: – Proteins linked to heritable coronary heart disease (CHD) could uncover new pathophysiological mechanisms of atherosclerosis. We report on the protein profile associated with a family history of early-onset CHD and whether the relation between proteins and coronary atherosclerotic burden differs according to family history status, as well as inferences from Mendelian randomization. M
Background: Type 2 diabetes (T2D) is a well-established risk factor for cataract. However, whether the causal effect on cataract differs by sex remains unclear. Determining whether this causal effect differs by sex could help resolve discrepancies in epidemiological studies regarding cataract risk in populations with diabetes. Methods: Using summary statistics of East Asian and European population
The evolutionary dynamics of diurnal Aletis moths (Lepidoptera: Geometridae: Sterrhinae) in the Afrotropics have been obscured by their allopatric distributions, significant inter- and intraspecific variation in adult and caterpillar phenotypes, and involvement in complex mimicry systems. Extensive phenotypic disparity, alongside conserved genital morphology and a lack of suitable material for gen
BACKGROUND: Previous studies, including ours (Wuestefeld et al., Brain, 2023), showed tau positron emission tomography (PET) uptake in medial temporal and neocortical regions of amyloid-beta (Aβ)-negative cognitively unimpaired (CU) individuals, associated with neurodegeneration and worse memory performance. To further understand if tau-PET uptake is clinically relevant in this population, we char
BACKGROUND: The tau-PET radiotracer [18F]flortaucipir enables in vivo detection of tau pathology in Alzheimer's Disease (AD) and has recently been FDA- and EMA-approved for clinical use. To support its implementation, we assessed tau-PET's positive predictive value (PPV) and negative predictive value (NPV) for clinico-pathological AD while accounting for age, amyloid-status, and pre-PET diagnostic
Examensarbetets titel: När marknaden får beskedet - En eventstudie av marknadsreaktion, betalningsmedel och institutionellt ägande vid företagsförvärv Seminariedatum: 15 januari 2026 Ämne/kurs: FEKH89, Examensarbete i finansiering på kandidatnivå, 15 högskolepoäng Författare: Nils Arvidsson, André Mellqvist & Emilian Rehnström Handledare: Elias Bengtsson Fem nyckelord: Abnormal avkastning,Title: When the Market Receives the News – An Event Study of Market Reaction, Payment Method and Institutional Ownership in Mergers and Acquisitions Seminar date: 15 January 2026 Course: FEKH89, Bachelor Thesis in Corporate Finance, Undergraduate Level, 15 credits Authors: Nils Arvidsson, André Mellqvist & Emilian Rehnström Advisor: Elias Bengtsson Key words: Abnormal return, short-term m
Title: Good at Home? Buy a Foreign Company Seminar Date: 2026-01-15 Course: Business Administration: Bachelor’s degree Project in Financial Management, Undergraduate Level, 15 credits Authors: Herman Barzangi, Simon Hägglund, Ivan Hörvin Advisor: Cociorva Anamaria Key words: Foreign direct investment, Cross-border mergers & acquisitions, Exchange rate, Location-advantage, Unemployment rat
Denna studie undersöker om noteringstidpunkt under den svenska IPO-vågen 2021 är förknippad med systematiska skillnader i långsiktig aktieavkastning mellan så kallade leaders och followers. Studien har en kvantitativ ansats och bygger på multipla linjära regressionsanalyser där långsiktig avkastning mäts med Buy-and-Hold Abnormal Return (BHAR). Datamaterialet omfattar 108 börsintroduktioner på denThis study examines whether the timing of listing during the Swedish IPO wave of 2021 is associated with systematic differences in long-term stock performance between so-called leaders and followers. The study adopts a quantitative approach and is based on multiple linear regression analyses, where long-term performance is measured using Buy-and-Hold Abnormal Return (BHAR). The dataset comprises 1
