Published 2 December 2020 The rapid development of new therapies in metastatic breast cancer (MBC), entails a need for improved prognostic and monitoring tools. Thymidine kinase 1 (TK1) is involved in DNA synthesis and its activity correlates to outcome in cancer patients. The aim of this study was to evaluate serum TK1 activity (sTK1) levels in MBC patients as a tool for prognostication and treat

https://www.lupop.lu.se/article/serial-evaluation-serum-thymidine-kinase-activity-prognostic-women-newly-diagnosed-metastatic-breast - 2025-07-05

Published 3 December 2020 Much neighborhood research has focused on contemporary and segregated cities in the United States, but less on small and more homogenous cities. Additionally, neighborhood conditions are often estimated using administrative borders, which bias results. We adopt a long-term perspective on the importance of childhood neighbors, using more realistic methods of neighborhood c

https://www.lupop.lu.se/article/social-context-nearest-neighbors-shapes-educational-attainment-regardless-class-origin - 2025-07-05

Published 3 December 2020 The prevalence of low LTPA among men and women were as follows: 13.9% and 12.3% among heterosexuals, 26.1% and 18.5% among bisexuals, 19.5% and 15.6% among homosexuals, 26.6% and 18.5% among others. Bisexual men and women and other men had higher odds ratio of low LTPA than heterosexuals in the final models, whereas gay and lesbian participants did not differ. Read more a

https://www.lupop.lu.se/article/sexual-identity-and-low-leisure-time-physical-activity-population-based-study - 2025-07-05

Published 4 December 2020 Poor health and unmet healthcare needs is common among people with substance use disorder (SUD) including patients in opioid substitution treatment (OST). Low health literacy (HL) is associated with poverty, low education and physical limitations, but is unexplored in an OST context. Read more at Health Literacy among Swedish Patients in Opioid Substitution Treatment: A M

https://www.lupop.lu.se/article/health-literacy-among-swedish-patients-opioid-substitution-treatment-mixed-methods-study - 2025-07-05

Published 4 December 2020 A nationwide study of individuals 20 years of age and older was conducted. Forearm fractures were defined as at least one registered diagnosis in the National Patient Register between January 1, 1998 and December 31, 2012. Cox regression analysis was used to estimate the relative risk (hazard ratios (HR) with 95% confidence intervals (CI)) of incident forearm fractures co

https://www.lupop.lu.se/article/distal-forearm-fractures-immigrant-groups-national-swedish-study - 2025-07-05

Published 5 December 2020 Parents and teachers play an important role in stimulating student motivation. The aim of this study was to examine if both parent and teacher enthusiasm could predict intrinsic motivation toward STEM activities, and if motivation would be associated with improved STEM achievement over one year in a one-year prospective examination of 288 Swedish students in their final y

https://www.lupop.lu.se/article/examining-how-parent-and-teacher-enthusiasm-influences-motivation-and-achievement-stem - 2025-07-05

Published 5 December 2020 The aim of this study was to establish creatinine growth curves separately for males and females that can be used to adjust childhood levels of serum creatinine to corresponding adult levels. Linear regression with fractional polynomials of age as independent variable was used to construct creatinine growth curves for a reference cohort (n = 83,157 samples from Belgium an

https://www.lupop.lu.se/article/novel-method-creatinine-adjustment-makes-revised-lund-malmo-gfr-estimating-equation-applicable - 2025-07-05

Published 6 December 2020 Thirty participants were randomized to the intervention group with four lifestyle-promoting text messages sent every week for six months. The control group received usual care. The baseline and follow-up visits for all 60 patients included measurements of blood pressure, anthropometrics, blood tests and a self-reported questionnaire. Read more at Full article: Text messag

https://www.lupop.lu.se/article/text-message-based-lifestyle-intervention-primary-care-patients-hypertension-randomized-controlled - 2025-07-05

Published 6 December 2020 We investigated use of the six major H1-antihistamines (cetirizine, clemastine, desloratadine, ebastine, fexofenadine and loratadine) and breast cancer-specific and overall mortality in a nation-wide register-based study of all 61,627 Swedish women diagnosed with breast cancer 2006–2013. Both peri- and post-diagnostic antihistamine use was analyzed using Cox regression mo

https://www.lupop.lu.se/article/desloratadine-and-loratadine-stand-out-among-common-h1-antihistamines-association-improved-breast - 2025-07-05

Published 7 December 2020 Cognitive function is an important outcome measure in patients with brain tumor, providing information about the patient’s clinical situation, treatment effects and possible progressive disease. The aim of this longitudinal study was to evaluate effects of the currently used radiation and chemotherapy treatment on cognitive function and to investigate associations between

https://www.lupop.lu.se/article/longitudinal-study-cognitive-function-glioma-patients-treated-modern-radiotherapy-techniques-and - 2025-07-05

Published 7 December 2020 Unacceptable pain was frequent. At the 15 year follow-up visit, 34% had unacceptable pain. Patients with unacceptable pain had, compared with patients with tolerable pain, significantly more disease activity, worse patient global assessment, and worse function on the Health Assessment Questionnaire and Signals of Functional Impairment, but the degree of joint destruction

https://www.lupop.lu.se/article/unacceptable-pain-barfot-inception-cohort-patients-rheumatoid-arthritis-long-term-study - 2025-07-05

Published 8 December 2020 An increasing number of people will live with disabilities in their homes and consequently, the need for home-based interventions will increase. Housing adaptations (HAs) are modifications to the physical home environment with the purpose to enhance independence for a heterogeneous group of people. Increasing the knowledge of the characteristics of HA clients by exploring

https://www.lupop.lu.se/article/identifying-and-validating-housing-adaptation-client-profiles-mixed-methods-study - 2025-07-05

Published 8 December 2020 As institutional forms of political engagement continue to decline, participation in protests steadily become more common. These trends are particularly strong among younger citizens. Previous research indicates that social factors can explain participation in political protests, and that younger citizens’ participation in protests is more affected by social ties than old

https://www.lupop.lu.se/article/young-protester-impact-belongingness-needs-political-engagement - 2025-07-05

Published 25 January 2020 Increased levels of circulating endostatin predicts cardiovascular morbidity and impaired kidney function in the general population. The utility of endostatin as a risk marker for mortality in the emergency department (ED) has not been reported. New publication in Clinical Biochemistry

https://www.lupop.lu.se/article/endostatin-predicts-mortality-patients-acute-dyspnea-cohort-study-patients-seeking-care-emergency - 2025-07-05

Published 26 January 2020 Primary treatment of cervical cancer in Sweden adhered to evidence-based standard of care. Areas of improvement include optimising treatment for stages III-IVA, and avoiding combining surgery and radiotherapy. New publication in Gynecologic Oncology

https://www.lupop.lu.se/article/primary-treatment-patterns-and-survival-cervical-cancer-sweden-population-based-swedish-gynecologic - 2025-07-05

Published 26 January 2020 Genetic and environmental factors both contribute to the development of Autism Spectrum Disorder (ASD) and Attention-Deficit/Hyperactivity Disorder (ADHD). One suggested environmental risk factor for ASD and ADHD is air pollution, but knowledge of its effects, especially in low-exposure areas, are limited. Here, we investigate risks for ASD and ADHD associated with prenat

https://www.lupop.lu.se/article/prenatal-exposure-air-pollution-potential-risk-factor-autism-and-adhd - 2025-07-05

Published 27 January 2020 The influence of gender on bipolar disorder is controversial and it is unclear if inpatient care differs between men and women. Here, we investigate for gender differences in the inpatient length of stay for Swedes admitted for bipolar disorder and explore other factors that could explain any observed association. New publication in Journal of Affective Disorders

https://www.lupop.lu.se/article/gender-influence-bipolar-disorder-inpatient-length-stay-sweden-2005-2014-register-based-study-0 - 2025-07-05

Published 27 January 2020 In this large, nationwide study, the prevalence of dystonia was high compared to previous studies, which partly may be explained by the high coverage of NPR. New publication in Parkinsonism & Related Disorders

https://www.lupop.lu.se/article/nationwide-prevalence-primary-dystonia-progressive-ataxia-and-hereditary-spastic-paraplegia - 2025-07-05

Published 28 January 2020 Hospitals in many countries do not record and analyze artificial hip and knee joint surgeries systematically, leading to a lack of reliable quality assurance data. Arthroplasty registers have the potential to alleviate this and improve quality of care and health care expenditures. In Germany, the current introduction of the Arthroplasty Register acts as a prototype for va

https://www.lupop.lu.se/article/hospitals-adoption-medical-device-registers-evidence-german-arthroplasty-register - 2025-07-05

Published 28 January 2020 Metabolically healthy obesity (MHO) remains controversial, since the underlying mechanisms behind this phenotype remain unclear. We aimed to investigate the characteristics of MHO, as well as prospective risks. New publication in Obesity Research & Clinical Practice

https://www.lupop.lu.se/article/metabolically-healthy-obesity-mho-malmo-diet-cancer-study-epidemiology-and-prospective-risks - 2025-07-05