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Archaeology and archaeological sciences are inherently spatial disciplines. Thus, it is of no surprise that GIS (Geographic Information System) has found its way into archaeological practice, providing an environment for data organisation, analysis and visualisation. Over the past few decades, archaeogeophysics has become an integral part of archaeological practice. The results of these studie
This thesis aims to clarify the risk that a confined aquifer can be contaminated from a spill of chlorinated solvents from a former dry-cleaning facility. This was investigated by conducting a case study at a former dry-cleaning facility in Bjärred that used PCE as a cleaning agent. The facility was active between the 1940s and 1970s, the spill from the process has had severe consequences with an
This paper aims to contribute to the already ongoing scientific discussion about socioeconomic factors and interpersonal trust. More specifically how parents educational level and view of one's self income influences this relationship. This study takes on a Swedish perspective and measures to what extent different variables affect the relationship. The analysis in this paper uses a multiple re
This study explores whether international female master’s students from non-European countries at Lund University achieve social integration, with a particular focus on friendships and sense of belonging. It also examines whether the university provides sufficient social and institutional resources to support integration. The purpose of the study is to understand what conditions Lund University pr
Ovarian cancer (OC) represents one of the most prevalent and lethal malignancies in women, with a need for novel treatments. A large obstacle in the development of OC therapies is the poor translation between preclinical and clinical results, partially attributable to the use of unsuitable models for drug screening. Common models such as cell lines, organoids, spheroids, tumor-on-a-chip, and anima
Cancer immunotherapy targeting the CD40 receptor on antigen presenting cells (APCs) is a promising treatment strategy that promotes priming of tumor-specific T cells and can revert a suppressive tumor microenvironment. CD40 signaling in dendritic cells (DCs) has been shown to promote maturation, enhance expression of MHC, costimulatory molecules and chemokine receptors, and induce IL-12 secretion,
Single-cell RNA sequencing (scRNA-seq) combined with immune receptor analysis is a significant breakthrough in immunology, enabling detect of gene expression and T-cell receptor (TCR) at the single-cell level in the same sample. However, current "gold standard" methods like 10x Genomics 5' V(D)J rely entirely on fresh samples, which severely limits their application in clinical studi
Denna studie ämnar identifiera olika aspekter av hur svenska värnpliktiga internaliseras genom den militära socialiseringsprocessen under den militära grundutbildningen. Särskilt analyseras hur militära normer, disciplin, hierarki samt roll- och identitetsskapande utvecklas och upprätthålls genom militära rutiner och anpassning till kollektivet inom institutionens ramar. Studien utgår från en kv
Small poikilothermic animals like insects rely on environmental sensing for survival. The ability to detect humidity through specialized sensory neurons is particularly critical, allowing them to maintain water balance across diverse environments. While recent studies have identified key receptors associated with humidity sensing, our understanding of the underlying molecular architecture of these
Background: Patients with relapsing–remitting multiple sclerosis (RRMS) experience fatigue and impaired information processing speed (IPS) frequently, even in the absence of clinical or radiological disease activity. Previous studies investigating associations between fatigue, IPS, neurofilament light chain (NfL) and glial fibrillary acidic protein (GFAP) have reported conflicting results. Objecti
In today’s world of increasing spatial inequalities, geopolitical tensions and global shifts in value chains, having a solid grasp of the spatial and multi-scalar dynamics that condition transition dynamics is of ever more importance. Initial theories of sustainability transitions have been criticised for being insufficiently equipped to assess the benefits, conflicts and unevenness that are const
Altermagnetism represents a recently established class of collinear magnetism that combines zero net magnetization with momentum-dependent spin polarization, enabled by symmetry constraints rather than spin-orbit coupling. This distinctive behavior gives rise to sizable spin splitting even in materials composed of light, earth-abundant elements, offering promising prospects for next-generation spi
Water diffusion gives rise to micron-scale sensitivity of diffusion MRI (dMRI) to cellular-level tissue structure. Precision medicine and quantitative imaging depend on uncovering the information content of dMRI and establishing its parsimonious hardware-independent fingerprint. Based on the rotational SO(3) symmetry, we study the geometry of the dMRI signal and the topology of its acquisition, id
The research study examines how employees in private and public sector organisations utilize AI-powered tools in organisational decision-making, focusing on the perceived benefits and challenges of their use. It further examines how such tools can enhance decision quality. A qualitative research design was employed, involving interviews with purposively selected employees from organisations in Swe
Ultraviolet radiation exposure and a fair pigmentation phenotype are well-established risk factors for primary cutaneous melanoma. However, the prognostic relevance of these risk factors is largely unexplored in metastatic disease. The aim of this study was to examine whether phenotypic characteristics and sun exposure patterns affect the prognosis of metastatic melanoma with immunotherapy availab
Escherichia coli O157:H7 is a non-invasive Shiga toxin (Stx)-producing pathogen that causes gastroenteritis and hemolytic uremic syndrome characterized by acute kidney injury. Stx binding to cells induces release of extracellular vesicles (EVs) containing the toxin. This study aimed to demonstrate the lethal effects of toxin-positive vesicles, and the importance of the Stx receptor, globotriaosylc
The songbird brain region called Cluster N has been implicated as important for low-light vision and/or the perception of Earth’s magnetic field for migratory orientation. This region of the visual Wulst is active in migratory songbirds under dim light conditions and an intact Cluster N is necessary for magnetic compass orientation in a nocturnally migrating songbird species. Given that magnetic f
