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As novel, anti-amyloid therapies have become more widely available, access to timely and accurate diagnosis has become integral to ensuring optimal treatment of patients with early-stage Alzheimer's disease (AD). Plasma biomarkers are a promising tool for identifying AD pathology; however, several technical and clinical factors need to be considered prior to their implementation in routine clinica
Global biodiversity is rapidly declining due to habitat degradation and genomic erosion, highlighting the urgent need to monitor endangered species and their genetic health. Temporal genomics and ecological modelling offer finer resolution than single-Time-point measurements, providing a comprehensive view of species' recent and future trajectories. We investigated genomic erosion and environmenta
How does new technology impact labor market outcomes? We address this question by examining the adoption of electricity in Sweden during the early 20th century. Leveraging detailed individual-level data that covers the entire labor market and exogenous variation in electricity access driven by proximity to hydro-power plants, we estimate the impact of electrification on individual labor market out
Permanent ponds are key landscape units that supply various ecosystem services. Notably, the export of aquatic subsidies to land via emerging insects may significantly influence terrestrial food webs. Polyunsaturated fatty acids (PUFA), which enhance consumer fitness, are among the essential exported components. The patterns and drivers of dietary exports from ponds via insects remain poorly known
Denna avhandling undersöker överlevnad och långsiktiga utfall hos kritiskt sjuka COVID-19-patienter som vårdades på intensivvårdsavdelningar (IVA) i Skåne mellan maj 2020 och maj 2021. Vi syftade till att fylla kunskapsluckor genom att genomföra en prospektiv, multicenterstudie där vi följde 498 IVA-patienter under tre år och utvärderade dödlighet, funktionella, fysiska och psykiska utfall, samt hThis thesis investigates the survival and long-term outcomes of critically ill COVID-19 patients admitted to intensive care units (ICUs) in the Skåne region of Sweden between May 2020 and May 2021. We aimed to address knowledge gaps by conducting a prospective, multicentre cohort study following 498 ICU patients over three years, evaluating mortality, functional, physical, and mental outcomes, as
Tool-based code review has been an established software engineering practice for at least a decade. However, while software development environments have improved significantly during this time with advanced features for code comprehension, refactoring, and AI support, code review tools have remained more static and are still centered around a two-way textual diff view with features similar to whe
A debated feature of civil society leadership is the (lack of) diversity among leaders. Another concern is the recruitment of leaders from the public and private sector. In this study we link these debates, analysing how civil society elite boundary crossing – that is, leaders from public and private sectors moving into elite positions in civil society – contributes to making the group of civil so
Accurate prediction of crack growth and strength in glued timber joints and components can be achieved by using cohesive laws in constitutive models. These laws represent the traction-separation relationship that measures the stress transmitted between crack faces in a cohesive zone, and can be obtained directly from experiments. However, studies on measuring the cohesive laws of wood adhesive bon
The paper provides an overview and preliminary results from ongoing research with the aim to evolve cross-laminated timber (CLT) into the next generation of Tailored Laminated Timber (TLT). This is done by exploring innovative concepts that optimize the mechanical performance, while simultaneously ensuring adherence to circular economy principles. The current study aims at investigating the potent
In previous years, substantial research has focused on walkability, primarily examining how the built environment affects walking behavior. However, these studies have predominantly defined walkability through physical and social factors, with limited exploration of its spatial dimension. This article seeks to address this gap by examining the spatiality of walkability through Lefebvre’s spatial tIn previous years, substantial research has focused on walkability, primarily examining how the built environment affects walking behavior. However, these studies have predominantly defined walkability through physical and social factors, with limited exploration of its spatial dimension. This article seeks to address this gap by examining the spatiality of walkability through Lefebvre’s spatial t
The paper provides an overview and preliminary results from ongoing research with the aim to evolve cross-laminated timber (CLT) into the next generation of Tailored Laminated Timber (TLT). This is done by exploring innovative concepts that optimize the mechanical performance, while simultaneously ensuring adherence to circular economy principles. The current study aims at investigating the potent
Groundwater hydraulics and aquifer processes are largely investigated using techniques that involve some kind of borehole test pumping. Such techniques are well established in the engineering and scientific community but are resource demanding. Time series analysis offer a collection of alternative methods that can be used to evaluate groundwater processes like recharge by using natural groundwate
Recording and analysing groundwater level data can reveal the nature and extension of groundwater processes like flow direction and recharge magnitude. The analyses can even indicate the influence of precipitation, evapotranspiration and runoff on the subsurface processes. However, such analyses are only possible when the recorded data cover relatively large periods of time at a suitable frequency
This study investigates the perception and understanding of climate-related risks among six energy-intensive and natural resource-based industry (ENRI) sectors using data from the CDP survey from 2020 to 2023. ENRI sectors, including fossil fuels; cement and concrete; chemicals; metallic smelting; refining; and forming; metallic mineral mining; and pulp and paper mills, are exposed to significant
The standard of proof at the International Court of Justice (ICJ) is a central, yet underexplored, aspect of its judicial decision-making. Although central in shaping both fact-establishment and judicial outcomes, the articulation and application of the standard of proof by the Court are marked by inconsistency and a lack of transparent justification. This inconsistency is often linked to an assumThe standard of proof at the International Court of Justice (ICJ) is a central, yet underexplored, aspect of its judicial decision-making. Although central in shaping both fact-establishment and judicial outcomes, the articulation and application of the standard of proof by the Court are marked by inconsistency and a lack of transparent justification. This inconsistency is often linked to an assum
