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BACKGROUND/OBJECTIVE: Bone remodeling is a critical process for skeletal health, and its dysregulation can lead to diseases like osteoporosis. While several Cyclin-Dependent Kinases (CDKs) are known to regulate bone metabolism, the function of CDK10 remains uncharacterized in this context. Human mutations in CDK10 cause the Al Kaissi syndrome, which involves severe skeletal defects, suggesting a
Cities worldwide face immense challenges in transitioning to a sustainable future. While being structurally and politically bound to continuous growth, the striving for a constant increase in production and consumption puts enormous pressure on our planet and its ecosystems. Degrowth has been proposed as a pathway to solving this dilemma. Although scholarly attention to urban degrowth has expanded
Corporate Social Responsibility (CSR) has become more important for companies in recent years, both as a marketing tool and a way to demonstrate as well as to maintain the organization's social, economical and environmental sustainability. While many organizations talk about sustainability, it is unclear how well this information reaches their frontline employees working in the stores. This th
The ability to hold listeners’ attention and prevent habituation is a crucial design feature for both biological and human-made distress and alarm signals, but their intrusive nature also causes stress and annoyance. To investigate what makes vocalizations distracting and annoying, we developed Self-Steered Sound Synthesis—a new experimental paradigm for studying voice perception, in which untrain
A snowmobile towed impulse radar measurement was used to produce detailed maps of ice-thickness in two areas, one on a local dome (the Hans Tausen ice cap), and one on an outlet glacier north thereof. A constant spatial sampling was achieved by using a device attached to the snowmobile's odometer. The bedrock reflection was automatically detected in the majority of the data, by using digital signa
Electrical resistivity tomography (ERT) is a widely used technique for imaging subsurface resistivity distributions, but conventional data acquisition strategies face trade-offs between resolution, efficiency, and data quality. Comprehensive datasets that maximize subsurface information are impractical to measure directly, motivating the development of ERT data reconstruction approaches that can g
Proton–proton collision data recorded by the ATLAS detector in 2011, at a centre-of-mass energy of 7 TeV, have been used for an improved determination of the W-boson mass and a first measurement of the W-boson width at the LHC. Recent fits to the proton parton distribution functions are incorporated in the measurement procedure and an improved statistical method is used to increase the measurement
A search is presented for new particles produced in proton-proton collisions at a centre-of-mass energy of 13 TeV that result in final states comprising a massive vector (W or Z) boson that decays hadronically and large missing transverse momentum. The data sample was collected with the ATLAS experiment at the Large Hadron Collider from 2015 to 2018 and corresponds to an integrated luminosity of 1
This paper presents a search for supersymmetric particles in models with highly compressed mass spectra, in events consistent with being produced through vector boson fusion. The search uses 140 fb−1 of proton-proton collision data at s = 13 TeV collected by the ATLAS experiment at the Large Hadron Collider. Events containing at least two jets with a large gap in pseudorapidity, large missing tran
The online information landscape is a site for contested ideas, but it is also a marketplace; under the platform economy, every engagement has monetary value. This setup encourages content creators to circulate the kinds of material most likely to capture attention, even if it is incendiary. Central to this business model are the algorithmic recommendation systems, which are designed to monetize a
The ATLAS tile calorimeter (TileCal) is the hadronic sampling calorimeter covering the central region of the ATLAS detector at the Large Hadron Collider (LHC). This paper gives an overview of the calorimeter’s operation and performance during the years 2015–2018 (Run 2). In this period, ATLAS collected proton–proton collision data at a centre-of-mass energy of 13 TeV and the TileCal was 99.65% eff
This master thesis investigates possibilities to use additive manufacturing in the form of Fused Fil- ament Fabrication (FFF) with the material Polylactic Acid, to replace polyurethane foams for less environmental impact. The mechanical properties of foam are difficult to mimic and there are few or no materials that are similar, hence the great challenge to replace it. The idea of using a flexible
Maskin- och monteringshallen i Varvsstaden i Malmö är en del av det tidigare Kockums-området, som under 1900-talet var en av stadens viktigaste industrimiljöer. Här byggdes fartyg som exporterades över hela världen, och området kom att spela en central roll i Malmös industriella utveckling. Hallen uppfördes 1912 och är idag ett kulturhistoriskt värdefullt industriminne som bevaras inom ramen för oThe Machine and Assembly Hall in Varvsstaden (Malmö, Sweden) is a heritage industrial building currently being refurbished into office space. As part of the renovation, the historic cast-iron framed windows will be complemented by an inner insulating window installed approximately 500 mm inside the existing line, creating an air cavity and altering the mechanical loading conditions of the original
Abstract Invasive species often have harmful effects on human activities and biodiversity. The Tapinoma nigerrimum complex includes three species that exhibit invasive traits and the ability to form supercolonies, including Tapinoma magnum and Tapinoma darioi . While these species are native to the Mediterranean basin, they have recently been reported as invasive in more northern regions of Europe
1. Grassland is an important habitat for butterflies and many other pollinating insects. Over half of the 501 European butterflies use grasslands as one of their main habitats.2. The Grassland Butterfly Index has been adopted by the EU as a key measure of progress towards the target of halting biodiversity loss, restoring nature in agro-ecosystems and reversing the decline in pollinators by 2030, 1. Grassland is an important habitat for butterflies and many other pollinating insects. Over half of the 501 European butterflies use grasslands as one of their main habitats.2. The Grassland Butterfly Index has been adopted by the EU as a key measure of progress towards the target of halting biodiversity loss, restoring nature in agro-ecosystems and reversing the decline in pollinators by 2030,
Cetaceans are negatively affected by anthropogenic activities, including acoustic and physical disturbance from boat traffic. Behavioural responses to such disturbances are context-dependent, and site-specific insights are needed for effective local management plans. In this study, the impact of speed and proximity of recreational boats on the swimming speed and surfacing interval of one of the mo
This dissertation examines the intense presence of the encounter with a number of artworks depicting sickrooms painted by Nordic artists by the end of the nineteenth century. To understand the intense presence enhanced through the encounter with these artworks, this dissertation argues that these paintings can be understood and examined as secular devotional images. Particular attention is devoted
