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ECHOES OF THE OIL SPILL OF 2019: ASSESSMENT OF THE PRESENCE OF PAH AND BTEX IN PRODUCTS FROM FISHING. The 2019 oil spill in Brazil caused widespread contamination in the Brazilian coast, posing risks to both animal and human health through seafood consumption. Therefore, this study aimed to evaluate seafood samples from different locations impacted by the oil spill. For this purpose, 44 samples un
Ion Migration and Redox Reactions in Axial Heterojunction Perovskite CsPb(Br1-xClx)3 Nanowire Devices Revealed by Operando Nanofocused X-ray Photoelectron Spectroscopy
Metal-halide perovskites (MHPs) have gained substantial interest in the energy and optoelectronics field. MHPs in nanostructure forms, such as nanocrystals and nanowires (NWs), have further expanded the horizons for perovskite nanodevices in geometry and properties. A partial anion exchange within the nanostructure, creating axial heterojunctions, has significantly augmented the potential applicat
Amyloids and Micelles : Self-assembly and co-assembly of Abeta and gangliosides
Extracellular plaques in Alzheimer’s disease contain Aβ peptides and ganglioside lipids such as GM1. Aβ monomers self-assemble into beta-sheet-rich fibrils when their concentration exceeds solubility, while GM1 monomers form spherical micelles above their critical concentration. This study examines the self-assembly of Aβ in the first two papers and its co-assembly with GM1 in the last two. In Pap
Multiomics profiling of DNA methylation, microRNA, and mRNA in skeletal muscle from monozygotic twin pairs discordant for type 2 diabetes identifies dysregulated genes controlling metabolism
BACKGROUND: A large proportion of skeletal muscle insulin resistance in type 2 diabetes (T2D) is caused by environmental factors.METHODS: By applying multiomics mRNA, microRNA (miRNA), and DNA methylation platforms in biopsies from 20 monozygotic twin pairs discordant for T2D, we aimed to delineate the epigenetic and transcriptional machinery underlying non-genetic muscle insulin resistance in T2D
Healthcare Utilisation in Danish Primary Care Among Patients With Low Back or Neck/Thoracic Spine Pain Before and After Assessment in Secondary Care
Objectives: To describe characteristics and primary healthcare utilisation in Danish patients with low back pain (LBP) or neck/thoracic spine pain (NTP) 8 years before and 2 years after assessment in secondary care. Methods: In this cohort study, we included patients aged ≥ 18 who were assessed at an outpatient spine clinic from 2013 to 2021 and linked self-reported information with national regis
Monoclonal gammopathy of undetermined significance and the risk of thrombotic events : Results from iStopMM, a prospective population-based screening study
Monoclonal gammopathy of undetermined significance (MGUS) is the asymptomatic precursor of multiple myeloma and related diseases but has also been associated with thrombosis. Prior studies have not been based on screened cohorts leading to bias. We assessed the risk of thrombosis in a cohort of 75 422 individuals over 40 years old who were screened for MGUS in Iceland. We also evaluated the associ
The association between novel urinary kidney damage biomarkers and coronary atherosclerosis in an apparently healthy population
Several novel urinary kidney damage biomarkers predict the progression of kidney disease. However, the relations of these biomarkers to atherosclerosis, a major consequence of kidney disease, are less studied. Urinary levels of several biomarkers, including kidney injury molecule-1 (KIM-1), osteopontin, epidermal growth factor, and Dickkopf-3, were assessed in participants enrolled in the Swedish
Concizumab prophylaxis in people with haemophilia A or haemophilia B without inhibitors (explorer8) : a prospective, multicentre, open-label, randomised, phase 3a trial
Background: Concizumab is an anti-tissue factor pathway inhibitor monoclonal antibody in development as a once-daily, subcutaneous prophylaxis for patients with haemophilia A or haemophilia B with or without inhibitors. We aimed to assess the efficacy and safety of concizumab in patients with haemophilia A or B without inhibitors. Here we report the results from the confirmatory analysis cutoff. M
Fira Öresundsbrons 25 år med att slopa gränskontrollerna
Pollinator foraging tactics have divergent consequences for the mating system of a tropical plant
AI - inte så smart som den tror
A Story of Combining Immunotherapy with Ultra-Hypo-Fractionated Radiation Therapy.
Denna berättelse om immunoterapi kombinerad med ultrahypo-fraktionerad strålterapi har sitt ursprung i den kliniska studie som på engelska benämdes "Brain Immune Gene Tumour Therapy" (BRIGTT) som professor Leif G, Salford i Lund initierade strax innan 2000-millienium-skiftet. Ett specifikt tumörvaccin framställdes baserat på tumörceller som han extraherade ur tumörvävnad från den gliom-patient han
Tropical deforestation reduces plant mating quality by shifting the functional composition of pollinator communities
The Landscape Genetic Signature of Pollination by Trapliners: : Evidence From the Tropical Herb, Heliconia tortuosa
A Cognitive Model of Visuospatial Complexity for Interactive Immersive Media Design
The development of immersive visuoauditory media brings to the fore several design challenges concerning cognitive human factors, such as visual perception, embodied interaction, and emotional engagement. With a focus on visual perception, our research emphasises a systematic study of embodied multimodal interaction in immersive settings and provides a cognitive model of visuospatial complexity th
Linking environmental and economic modelling for informing policymaking in agriculture
The European Green Deal recognises the importance of addressing the environmental challenges posed by agriculture to meet the global biodiversity and climate agendas. Environmental policymaking is needed to drive and speed up sustainability transitions in agriculture because the environmental consequences of agricultural activities are not generally reflected in production costs and lead to market
Joking nationalism: modes, moods, and national identity in foreign policy discourse on Swedish Reddit
Tuning the Organic Electrochemical Transistor (OECT) Threshold Voltage with Monomer Blends
A novel approach is introduced to modulate the threshold voltage of organic electrochemical transistors (OECTs) that are fabricated by electropolymerizing the channel material between the source and drain electrodes. To achieve this, we adjust the ratio of two water-soluble tri-thiophene monomers, which share the same backbone, but present either anionic or zwitterionic sidechains, during channel
Symptom experience and symptom distress in patients with malignant brain tumor treated with proton therapy : A five-year follow-up study
Background and purpose: Since patients with primary brain tumor are expected to become long-term survivors, the prevention of long-term treatment-induced side effects is particularly important. This study aimed to explore whether symptom experience and symptom distress change over five years in adults with primary brain tumors treated with proton therapy. An additional aim was to explore whether s