Analysis of the Innate Immune Response to Febrile UTI in Infants : Evidence of an Acute Cytokine Storm
Background: Infections trigger complex immune responses, with conserved as well as disease-specific characteristics. Methods: Proteomic screening technology and gene expression analysis were used here to define the immune response in infants, with their first episode of febrile urinary tract infection. Urine and peripheral blood samples were obtained at enrollment and at follow-up, after 6 months.
