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Bifunctional DNA glycosylases employ an active site lysine or the N-terminus to form a Schiff base with an abasic (AP) site base excision repair intermediate. For 8-oxoguanine DNA glycosylase 1 (OGG1), cleaving this reversible structure is the rate-determining step in the initiation of 8-oxoguanine (8-oxoG) repair in DNA. Evolution has led OGG1 to use a product-assisted catalysis approach, where t

Whereas theoretical attacks on standardized crypto primitives rarely lead to actual practical attacks, the situation is different for side-channel attacks. Improvements in the performance of side-channel attacks are of utmost importance.In this paper, we propose a framework to be used in key-recovery side-channel attacks on CCA-secure post-quantum encryption schemes. The basic idea is to construct

The atmosphere, ocean, and sea ice components in Earth system models are coupled via boundary conditions at the sea surface. Standard coupling algorithms correspond to the first step of an iteration, so-called Schwarz waveform relaxation. Not iterating is computationally cheap but introduces a numerical coupling error, which we aim to quantify for the case of a coupled single column model: the EC-

We discuss instrumentalism as a component of the social changes that accompanied the second industrial revolution, following particularly the case of Germany. These changes constituted a departure from the Enlightenment tradition of natural philosophers towards a new approach to knowledge. We claim that instrumentalism cannot be separated from the disciplining of science that produced the sciences

Water resources are a critical societal issue. As they are more and more limited, their distribution, usage and contamination are of vital importance. In the Beauce region, there are concerns on both the water quality and quantity because of farming and the related groundwater contamination. Since water is a vector of contamination, these questions require a precise vadose zone water content chara

We present an innovative hydrogeophysical approach for non-invasive quantification of the unsaturated water flow. For the water content measurements, we apply the Magnetic Resonance Sounding (MRS) method in the time-lapse mode. For inversion of MRS measurements, we approximate the subsurface by a horizontally stratified media. Laterally, the MRS estimated water content is averaged over the area be

Accurate grading of Oil Palm Fresh Fruit Bunches (FFB) is pivotal for maximizing agricultural yield, yet manual assessment in unstructured environments remains labor-intensive and subjective. While Convolutional Neural Networks (CNNs) offer an automated solution, the conventional strategy of scaling network depth often yields diminishing returns or overfitting on moderately sized datasets. To over

Previous research in various educational areas has shown that literary texts have much to contribute through offering perspectives, contexts, and ways of presenting content. The present study has a particular focus on science education. The purpose of science education is under debate, and research as well as large-scale frameworks such as PISA increasingly highlight student agency and action comp

Primary graft dysfunction (PGD), defined as ventricular dysfunction occurring within 24 hours after heart transplantation (HTx) in the absence of identifiable secondary causes, remains a major contributor to early post-transplant mortality. Over the past decade, there has been a growing understanding of the burden of PGD, the clinical relevance of PGD classification and severity grading, and effor

This thesis investigates how the experience of founding a youth-led social-innovation project can enhance young people’s agency for sustainable development, through a qualitative single-case study of Ashoka Belgium’s 2023 Youth for Change (Y4C) programme. Grounded in a social-constructivist, abductive logic, the study uses semi-structured interviews and mobilises three strands of scholarship—Socia

This thesis investigates how formal, national-level institutional factors shape the translation of R&D inputs into marketable innovation outputs in high- and medium-high-technology (HMHT) manufacturing. Focusing on Sweden’s persistent “innovation paradox”, high R&D intensity but comparatively modest commercialization—the study examines three institutional dimensions: domestic value added (

Abstract Title: Opportunities and Challenges of Establishing a Startup in Portugal Swedish Startup’s Perceptions of the Business Climate in Lisbon Seminar date: 28th of May 2025 Authors: Vendela Eriksson Supervisor: Tobias Karlsson Keywords: Business climate, business ecosystem, Lisbon, startup, entrepreneur, entrepreneurship Purpose: The purpose of this research is to examine the challenges and o

This thesis examines the extent to which Swahili agency shaped the Portuguese arrival as a turning point in East African economic history. Situating the encounter within the longue durée of Swahili integration into Indian Ocean trade networks, it aims to challenge interpretations that portray colonial contact as a purely exogenous rupture. Drawing on a bargaining-power framework, the study thus an

In February 2023, South Africa was placed on the Financial Action Task Force (FATF) greylist, raising concerns about the effects of this decision on the country. Existing studies focus mainly on macroeconomic indicators and legal analysis, with little evidence on how people experience greylisting. This thesis explores how key financial, regulatory and policy stakeholders perceive the economic, reg

This thesis explores the intersection of psychiatric expertise, artificial intelligence (AI), and infrastructural practices through an ethnographic study of the PERSONAE project—an initiative aiming to develop personalised, AI-driven digital treatment for depression within Danish mental healthcare. Drawing on four months of fieldwork, the analysis reveals how anticipatory logics, affective negotia

Micropollutant removal is a key component of the revised Urban Wastewater Treatment Directive (UWWTD) and can be achieved with ozonation. During ozonation, the composition of the wastewater matrix and the targeted treatment level for individual micropollutants or groups of such compounds affect ozone consumption. In this work, it was hypothesized that nitrite scavenging, the point of dosing (befor

Part of the online anthology of the artistic research project Costume Dramaturgies – The Dramaturgy of Things in Performance. The project explores the dramaturgy of things – as costume – in performance, where dramaturgy is understood as an assembly of human and nonhuman “things.”

Disruptions in gut microbiome are implicated in cardiometabolic disorders and other health outcomes. Antibiotics are known gut microbiome disruptors, but their long-term consequences remain underexplored. Here we combined individual-level data from the Swedish Prescribed Drug Register with fecal metagenomes of 14,979 adults to examine the association between oral antibiotic use over 8 years and gu