Sökresultat

Filtyp

Din sökning på "*" gav 533621 sökträffar

First-appearing islet autoantibodies for type 1 diabetes in young children : maternal life events during pregnancy and the child's genetic risk

AIMS/HYPOTHESIS: Psychological stress has long been considered a possible trigger of type 1 diabetes, although prospective studies examining the link between psychological stress or life events during pregnancy and the child's type 1 diabetes risk are rare. The objective of this study was to examine the association between life events during pregnancy and first-appearing islet autoantibodies (IA)

The Great Convergence? Gender and Unpaid Work in Europe and the United States

Over the past decades, men's and women's time use in industrialized nations has changed dramatically, suggesting a gender revolution. Women increased their time in paid work and reduced time in unpaid activities, while men increased their time in unpaid work, but not enough to compensate for women's retreat. We investigate developments regarding men's and women's unpaid work across Europe and the

“Tell me who you are” Latent semantic analysis for analyzing spontaneous self-presentations in different situations

The aim of the study was to analyze freely generated self-presentations through the natural language processing technique of Latent Semantic Analysis (LSA). Four hundred fifty-one participants (F = 360; M = 143) recruited from LinkedIn (a professional social network) were randomly assigned to generate 10 words to describe themselves to either an employer (recruitment-condition) or a friend (friend

Reflection-Based Source Inversion for Sparse Imaging of Low-Loss Composite Panels

This article presents a bistatic reflection-based imaging technique for electromagnetic testing of conductor-backed composite panels, which is based on an inverse formulation of the numerical problem at hand, and technically extends a previously demonstrated transmission-based system. The technique exploits the a priori assumption of pixel-based sparsity and retrieves the final image using data fr

Flow Characteristics and Heat Transfer of Supercritical n-decane in Novel Nested Channels for Scramjet Regenerative Cooling

A novel kind of regenerative cooling channel, a so-called nested channel, is proposed to further reduce the combustion chamber wall temperature of a scramjet. The supercritical n-decane heat transfer in the horizontal up-channel and horizontal down-channel with different flow directions are numerically investigated. The temperature distribution, flow field, and vortex structure are presented to di

Amperometric Flow-Injection Analysis of Phenols Induced by Reactive Oxygen Species Generated under Daylight Irradiation of Titania Impregnated with Horseradish Peroxidase

Titanium dioxide (TiO2) is a unique material for biosensing applications due to its capability of hosting enzymes. For the first time, we show that TiO2 can accumulate reactive oxygen species (ROS) under daylight irradiation and can support the catalytic cycle of horseradish peroxidase (HRP) without the need of H2O2 to be present in the solution. Phenolic compounds, such as hydroquinone (HQ) and 4

Time between milestone events in the Alzheimer's disease amyloid cascade

Objective: Estimate the time-course of the spread of key pathological markers and the onset of cognitive dysfunction in Alzheimer's disease. Methods: In a cohort of 335 older adults, ranging in cognitive functioning, we estimated the time of initial changes of Aβ, tau, and decreases in cognition with respect to the time of Aβ-positivity. Results: Small effect sizes of change in CSF Aβ42 and region

Medial temporal lobe connectivity and its associations with cognition in early Alzheimer's disease

Human episodic memory critically depends on subregions of the medial temporal lobe, which are part of functional brain systems such as the anterior-temporal and the posterior-medial system. Here we analysed how Alzheimer's pathology affects functional connectivity within these systems. Data from 256 amyloid-b-negative cognitively unimpaired, 103 amyloid-b-positive cognitively unimpaired, and 83 am

The brain attics : the strategic role of memory in single and multi-agent inquiry

M. B. Hintikka (1939–1987) and J. Hintikka (1929–2016) claimed that their reconstruction of the ‘Sherlock Holmes sense of deduction’ can “serve as an explication for the link between intelligence and memory” (1983, p. 159). The claim is vindicated, first for the single-agent case, where the reconstruction captures strategies for accessing the content of a distributed and associative memory; then,

Distinct growth phases in early life associated with the risk of type 1 diabetes : The teddy study

OBJECTIVE This study investigates two-phase growth patterns in early life and their association with development of islet autoimmunity (IA) and type 1 diabetes (T1D). RESEARCH DESIGN AND METHODS The Environmental Determinants of Diabetes in the Young (TEDDY) study followed 7,522 genetically high-risk children in Sweden, Finland, Germany, and the U.S. from birth for a median of 9.0 years (interquar

Health-related quality of life in early psoriatic arthritis compared with early rheumatoid arthritis and a general population

Objective: Both psoriatic arthritis (PsA) and rheumatoid arthritis (RA) have a significant impact on quality of life, but few reports have compared the two diseases. The current study assessed health-related quality of life (HRQoL) in PsA at diagnosis and after five years compared with early rheumatoid arthritis (RA) and a matched general population. Methods: Patients with early PsA and early RA i

Prey to predator body size ratio in the evolution of cooperative hunting—a social spider test case

One of the benefits of cooperative hunting may be that predators can subdue larger prey. In spiders, cooperative, social species can capture prey many times larger than an individual predator. However, we propose that cooperative prey capture does not have to be associated with larger caught prey per se, but with an increase in the ratio of prey to predator body size. This can be achieved either b

Operating theatre nurse specialist competence to ensure patient safety in the operating theatre : A discursive paper

Aim: To discuss specialist operating theatre nurses’ competence in relation to the general six core competencies and patient safety. Design: A discursive analysis of legal statutes and scientific articles. Methods: Swedish legal statutes and an overview of scientific articles on operating theatre nursing were deductively analysed and classified into healthcare providers’ general six core competenc

Radiographers’ academic development in Sweden : Towards and after a doctoral degree

Introduction: Radiography is a young discipline and having radiographers with a doctoral degree is central for its development. Academic development of this field in Sweden has been evolving. This study explored the diagnostic radiographers’ prerequisites for doctoral studies, post-doctoral employment and research activities. Methods: Data were collected through a questionnaire designed to give in

Left alone with the emotional surge – A qualitative study of midwives’ and obstetricians’ experiences of severe events on the labour ward

Background: Working on the labour ward entails being responsible for severe events during which a mother or baby may be injured or may die. Such events might affect decision-making, team-working, capacity for empathy, and patient safety. Aim: To explore midwives’ and obstetricians’ experiences, reactions and interpretations of being part of a severe event on the labour ward. Design. A qualitative

A Long-Term Coastal Evolution Model with Longshore and Cross-Shore Transport

This study encompasses the development of a long-term coastal evolution model with enhanced capabilities to simulate simultaneously the cross-shore and longshore evolution of the coast. The paper starts by reviewing the theory related to cross-shore and longshore sediment transport, which are the major components integrated in the model. Major advances were made by introducing modules to better ac

Ge quantum wire memristor

Despite being known of for decades, the actual realization of memory devices based on the memristive effect is progressing slowly, due to processing requirements and the need for exotic materials which are not compatible with today's complementary-metal-oxide-semiconductor (CMOS) technology. Here, we report an experimental study on a Ge quantum wire device featuring distinct signatures of memristi

In situ studies of the cathodic stability of single-crystalline IrO2(110) ultrathin films supported on RuO2(110)/Ru(0001) in an acidic environment

We investigate with in situ surface X-ray diffraction (SXRD) and X-ray reflectivity (XRR) experiments the cathodic stability of an ultrathin single-crystalline IrO2(110) film with a regular array of mesoscopic rooflike structures that is supported on a RuO2(110)/Ru(0001) template. It turns out that the planarity of the single-crystalline IrO2(110) film is lost in that IrO2(110) oxide domains delam

Microbial Regulation of Enteric Eosinophils and Its Impact on Tissue Remodeling and Th2 Immunity

Eosinophils have emerged as multifaceted cells that contribute to tissue homeostasis. However, the impact of the microbiota on their frequency and function at mucosal sites remains unclear. Here, we investigated the role of the microbiota in the regulation of enteric eosinophils. We found that small intestinal (SI) eosinophilia was significantly greater in germ-free (GF) mice compared to specific