SeqCapAnalyst is a pipeline to process .fastq files, producing the standard files as well as statistics useful for singling out good targets for Sequence Capture probes. Rather than speed, it is optimized for flexibility and ease of modification. SeqCapAnalyst is predominantly written in bash, with one module written in Python. The pipeline was tested on sequence capture data which was obtained f

Mikropartiklar är mer än 100 gånger mindre än ett hårstrå. De brukar användas som behållare för läkemedel eller för att markera enskilda molekyler. För dessa ändamål måste ytan på mikropartiklarna modifieras med olika kemiska grupper. Jag har i detta arbete undersökt olika metoder för att binda in protein till mikropartiklar. Som modellsystem valdes mikropartiklar tillverkade av plasten polystyrenMicroparticles of various sizes carrying different surface modifications have numerous technological and biomedical applications, for example to create a larger target for a molecular receptor by binding multiply ligands to the surface of the microparticle. The aim of the present work is to study how to most efficiently couple protein molecules to the surface of such microparticles. In the current

Syftet med den här uppsatsen var att undersöka satsbetoningsmönstret hos exklamativer och vad det gör för den semantiska tolkningen av exklamativen. Detta undersöktes dels genom introspektion, och dels i ett perceptionsexperiment av att-exklamativer. Resultatet av introspektionen visade att att-exklamativers betoning i vissa fall skiljer sig från som- och wh-exklamativers. Detta gäller vid signale

In today's society, much energy is used and all energy use (e.g. heat, electricity) affects the environment. Greenhouse gas emissions from energy affect the climate of the earth and increase the natural greenhouse effect. Environmental impact because of energy use causes both local and global problems. Efficient energy use in buildings is a prerequisite for dealing with climate issues and in t

An evaluation of the current and previous Rosa rugosa growth on Kieler Ort, Germany, with the aim to predict the rose coverage in future, under consideration of environmental factors. Kieler Ort, a rather isolated island in the southwest Baltic Sea is representing a unique environment which is protected for its landscape, nature, flora and fauna and serves as a bird sanctuary. Rosa rugosa, as one

Enligt Newsecs rapport från 2016 söker företag idag kontor som har effektiv kontorsyta med stor flexibilitet vad det gäller både area och hyresavtal. Deras analys är att sådana kontor kommer fortsätta att efterfrågas. Vad som menas med flexibla hyresavtal är inget som är självklart i branschen men i detta examensarbete innebär sådana hyresavtal kortare hyrestider och mindre ytor för varje aktör soAccording to Newsec's report from 2016 companies are looking for offices that have efficient office space with great flexibility in terms of both area and lease. Their analysis is that such offices will continue to be demanded. What is meant by flexible real estate leases is nothing that is obvious in the industry but in this paper such leases mean less lease times and less space for each part

The Rural Development Program 2014-2020, is a way of reducing urbanization and creating more equal conditions between urban and rural areas. However, since fiberoptic cables is built on commercial terms, incentives for digging fiber in rural areas are lacking, which means that different types of support are required for construction to be possible. The administrative and financial difficulties req

Neurodegenerative disease or injury often result in devastating consequences for affected individuals. Treatment options available remain inefficient, and the hunt for new innovative approaches to halt and reverse the effects of neural cell loss continues. Regenerative medicine focuses on a combination of cell transplantation coupled with tissue engineering approaches (3D scaffolds and biomaterial

Cellular Migration: Natures compass to preserve the Blood-Brain–Barrier The Blood-Brain-Barrier (BBB) is a specialized and essential structure to ensure optimal physiological conditions in the brain. It separates the circulating blood and its components from sensitive neurons in the brain limiting and selecting which constituents that are transported from blood to brain and vice versa. Pericytes

Malaria parasites belong to the genus Plasmodium, which infects a diverse range of host. Plasmodium relictum is one of the most widespread species of avian malaria with its diverse host ranges, causing severe disease and high mortality in many parts of the world. Plasmodium undergoes a complex lifecycle infecting two hosts: the arthropod vector and the vertebrate host. Recent RNA-seq development h

This paper attempts to expose the factors influencing political participation in the Kibera informal settlement in Nairobi, Kenya. To this end, an extensive survey was carried out in three of the five political wards in Kibera. Prior comparative studies of political participation have reached the somewhat simplistic conclusion that poor citizens are a politically inactive group in society. A handf

Gamification is an increasingly common motivational tool, and knowledge management is rising to become an important part of strategies in knowledge intensive organizations. The academic infancy of gamification and the relatively young field of knowledge management provide ample opportunities for novel research. This thesis attempts to understand what needs to be considered when designing a practic

This study aims to evaluate Malmö stad integration work regarding the integration of incoming overseas women to the employment sector. In order to understand what Malmö stad integration work means, the overall establishment policy of the governmental offices is evaluated. Malmö stad receives six hundred immigrant every year. In Malmo there is already housing shortage, and Sweden is already faced

Improving teamwork has become a major safety goal for healthcare organizations. Audit tools currently available are useful, but they remain inadequate because they are reactive and fail to provide context for “the interaction between people and the operational context (i.e., organizational, regulatory and environmental factors) within which people discharge their operational duties” (Maurino, 2005

In my thesis work I have explored the relationship between site and building. As the focal point for my studies I have had a, too me, very familiar site in the outskirts of the village of Höör in the centre of Skåne. e site has been the property of my grandfather who took care of the place until he got to old to do it. I spend a lot of time here when visiting my grandparents as a kid. Today my mot

Undersökningen fokuserar på att reda ut privata aktörers förhållanden till Lennart Lundquists ekonomi- och demokrativärde. Ambitionen är inspirerad av Lundquists teoretiska tolkning av privata aktörers värdeförhållande, och varningen som han därefter målar upp för privatiseringen av offentlig förvaltning. Närmare fokuserar studien därför på att reda ut huruvida privata aktörer prioriterar ekonomiv

The consumption of plastic bags is a global problem that leads to increased concentration of plastic in the world oceans. In 2014, annual consumption of plastic carrier bags amounted to around 100 billion in the EU, which corresponds to an average of about 200 bags per person per year, of which many plastic bags are used only once and/or end up as waste in nature. This thesis is a comparative case

There has been plenty of debate on the relation between civil society and democracy. This case study of Poland thus adds to this debate. The research was done through analysing reports from civil society organisations and conducting two interviews with civil society organisations. The conclusion is that although civil society organisations in Poland can have a positive impact on democracy, there a

On 9 December 2015, the United Nations Security Council (UNSC) unanimously adopted Resolution 2250 on Youth, Peace and Security (YPS) in a move that gave recognition to the work young people are doing to promote peace. In an investigation to critically examine whether UNSCR 2250 recognizes youth agency for peace or whether it may be used to securitize young people, this thesis analyzes the discurs

The aim of this master thesis was to develop and build a prototype of separate hydrofoils compatible with a Europe-dinghy (A common, single sail, one-person dinghy), to be used as a proof of concept. This was to be done without causing any permanent changes to the dinghy’s hull. The consulting firm Essiq AB supported the project. Extensive benchmarking of existing foiling dinghies, already on the