Cerebral pares (CP) är den vanligaste orsaken till motorisk funktionsnedsättning hos barn och ungdomar och årligen föds ca 200 barn med CP i Sverige. Symtomen vid CP varierar, men karaktäriseras av bland annat nedsatt rörelseförmåga och nedsatt förmåga att stabilisera kroppen. Nästan åtta av tio vuxna med CP besväras av korta och spända muskler, snedställda leder och smärta som påverkar deras funkBackgroundIndividuals with cerebral palsy (CP) have an increased risk for scoliosis, especially those with low gross motor function, affecting both quality of life and overall function. The aims were to increase the knowledge on the development of, and predictors for scoliosis and the use of spinal orthoses in individuals with CP, and also to evaluate the Caregiver Priorities and Child Health Inde

The Yellow River is a river where serious ice disasters frequently take place in winter. In recent years, the stable frozen period has decreased and the frequency of intermittent freeze periods has increased. After analysing the main factors influencing the ice regime, the prediction factors can be selected. Using multiple linear regression (MLR) and artificial neural network (ANN) methods, this p

Quantum confined devices of 3D topological insulators are proposed to be promising and of great importance for studies of confined topological states and for applications in low-energy-dissipative spintronics and quantum information processing. The absence of energy gap on the topological insulator surface limits the experimental realization of a quantum confined system in 3D topological insulator

Second primary cancers (SPCs) are becoming a common cancer entity, which may interfere with survival in relatively benign first primary cancers. We examined the hypothesis that immune dysfunction may contribute to SPCs by assessing SPCs associated with known immune responsive skin cancers, invasive and in situ squamous cell carcinoma, Kaposi sarcoma, and Merkel cell carcinoma. Cancers were identif

The latitudinal diversity gradient (LDG) is one of Earth’s most iconic biodiversity patterns and still one of the most debated. Explanations for the LDG are often categorized into three broad pathways in which the diversity gradient is created by (1) differential diversification rates, (2) differential carrying capacities (ecological limits), or (3) differential time to accumulate species across l

Background The impact of baseline anemia in a contemporary acute coronary syndrome (ACS) population undergoing percutaneous coronary intervention in the era of predominant radial artery access, potent P2Y12 inhibition, and rare use of glycoprotein IIb/IIIa inhibitors has not been adequately studied. Methods and Results ACS patients who underwent percutaneous coronary intervention between 2014 and

Background: Laccases are multicopper oxidases, which are assigned into auxiliary activity family 1 (AA1) in the CAZy database. These enzymes, catalyzing the oxidation of phenolic and nonphenolic substrates coupled to reduction of O2 to H2O, are increasingly attractive as eco-friendly oxidation biocatalysts. Basidiomycota laccases are well characterized due to their potential in de-lignification of

Diabetes mellitus (DM) is a worldwide disease that affects 9% of the adult world population and type 2 DM accounts for 90% of those. A common consequence of DM is kidney complications, which could lead to kidney failure. We studied the potential effects of treatment with insulin and the glucagon-like peptide 1 receptor (GLP-1R) agonist liraglutide on the diabetic kidney proteome through the use of

We establish the Hasse principle for smooth projective quartic hypersurfaces of dimension greater than or equal to 28 defined over Q.

Our world is changing fast. On one hand, technological developments provide us with new and powerful electronics devices on almost a weekly basis. On the other hand, the end-user of these electronics is now rarely required to actually configure the devices, as everything is automated. This "de-empowerment" of the end-user may be detrimental to the scientific community. This is because the unique c

Background: Prophylactic central neck dissection in patients with papillary thyroid carcinoma is controversial. Sentinel node biopsy might be an adjunct to optimize surgical treatment for these patients. Earlier studies reported inconsistent detection rates and diagnostic value of this technique, and the role of sentinel lymph node biopsy in thyroid cancer needs to be established. Patients and met

When a literary text is translated from a dominated to a dominating language, Yvonne Lindqvist (2018) observes, it generally undergoes a cosmopolitanizing process. Consecrated by the dominating literary culture, the text is lifted up to a transnational level and deemed significant for an international readership. Lindqvist’s observation is confirmed by the English translations of Swedish working-c

Sml1 is a small ribonucleotide reductase (RNR) regulatory protein in Saccharomyces cerevisiae that binds to and inhibits RNR activation. NMR studies of 15N-labeled Sml1 (104 residues), as well as of a truncated variant (residues 50−104), have allowed characterization of their molecular properties. Sml1 belongs to the class of intrinsically disordered proteins with a high degree of dynamics and ver

Aim: Studies indicate that reduced foetal haemoglobin levels are related to increased neonatal morbidity rates. This study investigated the relationships between sampling-related blood loss and adult blood transfusions administered during postnatal days 1-14 and the development of severe neonatal morbidities in extremely preterm infants born before 28 weeks of gestation. Methods: The medical files

Background: The Heart School is a standard component of cardiac rehabilitation after myocardial infarction in Sweden. The group-based educational intervention aims to improve modifiable risks, in turn reducing subsequent morbidity and mortality. However, an evaluation with respect to mortality is lacking. Aims: Using linked population registries, we estimated the association of attending Heart Sch

Epithelial ovarian cancer (EOC) is considered to secrete various factors in order to promote peritoneal dissemination through cell-to-cell interaction between cancer and mesothelial cells. We previously revealed that TGF-β secreted from EOC induces normal human peritoneal mesothelial cells (HPMCs) to differentiate into cancer-associated mesothelial cells (CAMCs). However, the relationship between

Latin America has constituted a recent example of inclusive growth by reducing poverty and income inequality simultaneously during the latest commodity boom. Against the backdrop of non-inclusive and non-transformative nature of commodity booms, we ask whether growth of agriculture was able to speed up structural transformation, and, relatedly, if agricultural growth was inclusive. We examine 16 c