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The current study focused on the surface integrity issues associated with broaching of Inconel 718 and the structural stability of the broached specimen at high temperatures, mainly involving the microstructural changes and residual stress relaxation. The broaching operation was performed using similar cutting conditions as that used in turbo machinery industries for machining fir-tree root fixing
The nocturnal Bogong moth (Agrotis infusa) is an iconic and well-known Australian insect that is also a remarkable nocturnal navigator. Like the Monarch butterflies of North America, Bogong moths make a yearly migration over enormous distances, from southern Queensland, western and northwestern New South Wales (NSW) and western Victoria, to the alpine regions of NSW and Victoria. After emerging fr
Objective: The present study reports on the application of a Swedish translation of the audiologist occupational stress questionnaire (AOSQ) on audiologists working in Sweden. The relations between AOSQ scores and perceived effort, perceived rewards, coping strategies at work, demographic variables such as salary, education length, practise length, and practice type were tested. Design: A cross-se
Has rising trade integration between the U.S. and China contributed to the polarization of U.S. politics? Analyzing outcomes from the 2002 and 2010 congressional elections, we detect an ideological realignment that is centered in trade-exposed local labor markets and that commences prior to the divisive 2016 U.S. presidential election. Exploiting the exogenous component of rising trade with China
Optogenetics is one of the most powerful tools in neuroscience, allowing for selective control of specific neuronal populations in the brain of experimental animals, including mammals. We report, for the first time, the application of optogenetic tools to human brain tissue providing a proof-of-concept for the use of optogenetics in neuromodulation of human cortical and hippocampal neurons as a po
In this paper infinitesimal elasto-plastic based topology optimization is extended to finite strains. The employed model is based on rate-independent isotropic hardening plasticity and to separate the elastic deformation from the plastic deformation, use is made of the multiplicative split of the deformation gradient. The mechanical balance laws are solved using an implicit total Lagrangian formul
The Value of a Statistical Life (VSL) is a widely used measure of the value of mortality risk reduction. Since VSL should reflect preferences and attitudes to risk, there are reasons to believe that it varies depending on the type of risk involved. It has been argued that cancer should be considered a “dread disease”, which supports the use of a “cancer premium”. The objective of this study is to
For the assessment of value of new therapies in healthcare, Health Technology Assessment (HTA) agencies often review the cost per Quality-Adjusted Life-Years (QALY) gained. Some HTAs accept a higher cost per QALY gained when treatment is aimed at prolonging survival for patients with a short expected remaining lifetime, a so called End-Of-Life (EoL) premium. The objective of this study is to elici
Alt a 1 is a highly allergenic protein from Alternaria fungi responsible for several respiratory diseases. Its crystal structure revealed a unique β-barrel fold that defines a new family exclusive to fungi and forms a symmetrical dimer in a butterfly-like shape as well as tetramers. Its biological function is as yet unknown but its localization in cell wall of Alternaria spores and its interaction
Multiplicity-correlation measurements provide insight into the dynamics of high-energy collisions. Models describing these collisions need these correlation measurements to tune the strengths of the underlying QCD processes which influence all observables. Detectors, however, often possess limited coverage or reduced efficiency that influence correlation measurements in obscure ways. In this paper
Objective Bayesians hold that degrees of belief ought to be chosen in the set of probability functions calibrated with one’s evidence. The particular choice of degrees of belief is via some objective, i.e., not agent-dependent, inference process that, in general, selects the most equivocal probabilities from among those compatible with one’s evidence. Maximising entropy is what drives these infere
Retired Lutheran pastor Ambilikile Mwasapila became the most celebrated healer in Eastern Africa for half a year in 2011. His healing consists of an herbal potion, brewed according to the recipe he got from God in dreams. According to Rev. Mwasapila, the potency of the medicine stems from the presence of the Word of God in it. It is efficient only when administered by him. He perceives himself as
Strong-field phenomena driven by an intense infrared (IR) laser depend on during what part of the field cycle they are initiated. By changing the sub-cycle character of the laser electric field it is possible to control such phenomena. For long pulses, sub-cycle shaping of the field can be done by adding a relatively weak, second harmonic of the driving field to the pulse. Through constructive and
It is of contemporary interest to fabricate nanowires having quantum confinement and one-dimensional subband formation. This is due to a host of applications, for example, in optical devices, and in quantum optics. We have here fabricated and optically investigated narrow, down to 10 nm diameter, wurtzite GaAs nanowires which show strong quantum confinement and the formation of one-dimensional sub
