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Hypercalcemia in monoclonal gammopathy of undetermined significance (MGUS) presents a clinical challenge since it may indicate progression to multiple myeloma (MM) but could also be due to a multitude of unrelated disorders. To inform the approach to this clinical challenge, we conducted a nested cohort study within the iStopMM screening study. Of the 75,422 Icelanders aged 40 years and above who

This study is concerned with the distribution of the definite article inGerman with plural nominals that have a generic reading. In Standard German,genericity is typically expressed by bare nouns (Tiger sind gefährlich‘Tigers aredangerous’). Many researchers have claimed that there is variation in articleuse in the expression of generic reference in German (e.g., Brugger 1993; Longobardi 1994; Kri

To investigate whether coronary artery disease (CAD) burden is associated with plasma levels of the myocardial biomarkers Troponin I (TropI) and NT-proBNP in a large population-based sample using a cross-sectional design. Coronary computerized tomography (CT) angiography was performed in 25,859 subjects without a history of atherosclerotic disease from SCAPIS study (age 50-65, 52% women). TropI an

Like Einstein's general theory of relativity is concerned with explaining the basics of an observable experience – i.e., gravity – most people take for granted that Chomsky's theory of generative grammar (GG) is concerned with the basic nature of language. This chapter highlights a mere subset of central constructs in GG, showing how they have featured prominently and thus shaped formal linguistic

The study analyzed the performance of Doho Rice Irrigation Scheme (DRIS), the largest public irrigation scheme in Uganda, using (1) water supply indicators comprising relative water supply (RWS), relative irrigation supply (RIS), and water delivery capacity (WDC) related to water supply from the system in relation to scheme crop water demand for the 2018–2019 growing season; and(2) water balance r

Feedback loops are among the core notions in systems thinking – and the various fields of theory and practice that draw on it, including systemic design. We use these notions to develop methodological approaches, conceptualise processes, assess the adequacy of solutions, and anticipate how the design object may interact with its immediate surroundings and beyond. In my presentation, I discuss the

At a geological time-scale, seas rise aloft and mountains crumble. We are currently in the middle of a debate on whether—in order to acknowledge the pervasive and geologically significant traces of human action on the planet—our present era should be labelled the “Anthropocene”, and if so, what would be the cut-off date for the commencement of that era. At the same moment, we are already contempla

Nanowire (NW) optoelectronic and electrical devices offer unique advantages over bulk materials but are generally made by contacting entire NW arrays in parallel. In contrast, ultra-high-resolution displays and photodetectors require electrical connections to individual NWs inside an array. Here, we demonstrate a scheme for fabricating such single NW vertical devices by contacting individual NWs w

Detta är den sjätte romanen i romanserien om Thierry av Liège

UNLABELLED: The aim of this systemic review and meta-analysis was to examine the differences in caesarean section rates across European regions and at a country level by utilizing the Robson classification system. The study has compared caesarean rates across European regions using the Robson classification to identify the drivers of caesarean section use. This review shows significant variations

Anion exchange membranes (AEMs) carrying N-spirocyclic quaternary ammonium cations generally have a high alkaline stability because the unstrained ring conformations of this type of bicyclic cation. Here, we have prepared a series of N-spirocyclic quaternary ammonium ionenes (spiro-ionenes) using a diphenyl-functionalized monomer with a di-N-spiro-isoindolium moiety containing two N-spiro cations.

The family of methodologies and approaches used and developed by the systemic design community has several characteristics that could play a vital role in supporting collective visioning and concerted action for sustainability transitions. It offers heuristics for bridging scales and domains, and tools for constructing spaces of joint reflection, visioning and decision-making. These methodologies

Extruded mortar joints, resulting from suboptimal workmanship in bricklaying, bridge air gaps within cavity external walls. This phenomenon establishes a connection between brick masonry claddings and adjacent layers (such as insulation or weather-resistive barriers), inadvertently intensifying water penetration due to wind-driven rain (WDR) loads. This study utilises a probabilistic analysis in c

In Sweden, cavity walls constructed with autoclaved aerated concrete (AAC) inner leaves and clay brick outer leaves were a common design choice during the 1950s to 1970s. These walls often result in relatively extensive heat losses, leading to reduced indoor thermal comfort. Further, moisture-related issues like frost damage and interior dampness are reported for this wall type. This indicates the

Neuroblastoma (NB) is the most common cancer in infancy with an urgent need for more efficient targeted therapies. The development of novel (combinatorial) treatment strategies relies on extensive explorations of signaling perturbations in neuroblastoma cell lines, using RNA-Seq or other high throughput technologies (e.g. phosphoproteomics). This typically requires dedicated bioinformatics support

Objective Elite para athletes report a high incidence of sports injuries. Research suggests that athletes’ strategies to manage adversities may influence the sports injury risk, but knowledge about para athletes’ coping behaviours and their association with injuries is limited. The aim was to describe the distribution of coping behaviours in Swedish elite para athletes by sex, age, impairment, spo

Vardagstrycket på UB i Lund innehåller många priskuranter. Här ligger fokus på priser för död och begravning under tidigt 1900-tal. Begravningskostnader motsvarande en månadslön för en arbetare innebar inga extravaganser. En påkostad begravning kunde däremot handla om summor motsvarande flera årslöner för en arbetare.