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Emotional and behavioral problems during childhood raise the risk of subsequent developmental of mental disorders. Our aim was to study the association between maternal metal and trace element concentrations during gestation and these problems in 9 year-old children. The study sample comprised Spanish mother-child pairs in the INMA project (n = 1003). Metals and trace elements (As, Cd, Co, Cu, Mo,
The Tabernas–Alhabia Basin is a structural depression situated in the province of Almería, southeastern Spain. The basin is filled with Neogene, Pliocene, and Pleistocene sediments resting discordantly on a Paleozoic metamorphic basement. During the marine Tortonian sedimentation, a bed of breccia (Gordo megabed) was formed. It consists of rotated sedimentary megablocks commonly capped and/or surr
Interior automotive plastic components are often manufactured by injection moulding since this technique enables cost-efficient manufacturing, large design freedom, and easy integration of functions. However, to obtain a high-quality impression, it is important to produce components with uniformity in texture, colour, and gloss. Unfortunately, this is rather difficult since a large number of mater
Translating machine learning research into clinical practice has several challenges. In this paper, we identify some critical issues in translating research to clinical practice in the context of medical image segmentation and propose strategies to systematically address these challenges. Specifically, we focus on cases where the model yields erroneous segmentation, which we define as corner cases
Objective: Patient-specific virtual reality (VR) simulation of cochlear implant (CI) surgery potentially enables preoperative rehearsal and planning. We aim to gather supporting validity evidence for patient-specific simulation through the analysis of virtual performance and comparison with postoperative imaging. Methods: Prospective, multi-institutional study. Pre- and postoperative cone-beam CT
The aim of this paper is to contribute to the theorizing of diversity management, studied from a postcolonial perspective. This paper draws on an empirical study of a Swedish municipal school for adults in order to theorize how construction of privileged and disadvantaged ethnic identities is an integral diversity management practice, situated in the Swedish context. Further, the paper looks not o
Electrification of many industries using off-road high power machines presents several problems. In order to analyse the viability of different solutions the logistics, machine operation and power management have to be analysed. In this paper a model is presented that in a novel way combines these problems into a complete system model that can be optimized on several levels. Complex charging schem
Borrowing hydrogen (BH) reactions are very useful for the sustainable synthesis of C−C and C−N bonds. They generally operate with transition metal-based catalysts along with stoichiometric/catalytic amounts of added base. Here we report that two catalytic transformations, generally carried out with the BH methodology, i. e. N-alkylation of amines with alcohols and β-alkylation of secondary alcohol
The extent to which genetic variations contribute to interindividual differences in weight loss and metabolic outcomes after bariatric surgery is unknown. Identifying genetic variants that impact surgery outcomes may contribute to clinical decision making. This review evaluates current evidence addressing the association of genetic variants with weight loss and changes in metabolic parameters afte
Precision cancer medicine is a multidisciplinary team effort that requires involvement and commitment of many stakeholders including the society at large. Building on the success of significant advances in precision therapy for oncological patients over the last two decades, future developments will be significantly shaped by improvements in scalable molecular diagnostics in which increasingly com
Agricultural extension, or advisory services, have a key role to play in supporting farmers’ learning and adoption of new practices and technologies. This paper analyses gaps and needs which require addressing in order for extension systems to more effectively contribute to the upscaling of ecological intensification approaches in East African smallholder agriculture. Our starting point is the pus
Background: Fibrotic atrial cardiomyopathy plays an important role in determining the outcome of ablation in patients with atrial fibrillation (AF). Two main methods are being used for the evaluation of fibrosis: voltage-based high-density (HD) electroanatomical mapping (EAM) and late gadolinium enhancement MRI (LGE-MRI). The comparability between both methods in detecting fibrosis has not been sy
We consider Toeplitz determinants whose symbol has: (i) a one-cut regular potential, (ii) Fisher-Hartwig singularities and (iii) a smooth function in the background. The potential is associated with an equilibrium measure that is assumed to be supported on the whole unit circle. For constant potentials, the equilibrium measure is the uniform measure on the unit circle and our formulas reduce to we
Osteoporotic fracture is among the most common and costly of diseases. While reasonably heritable, its genetic determinants have remained elusive. Forearm fractures are the most common clinically recognized osteoporotic fractures with a relatively high heritability. To establish an atlas of the genetic determinants of forearm fractures, we performed genome-wide association analyses including 100,0
This chapter points to the fact that notwithstanding the global spread of English-medium instruction (EMI) and a growing body of research into EMI in different disciplines and higher education contexts, transnational, and comparative studies on EMI that draw on large-scale cross-institutional data are extremely scarce. Hence, the TAEC Corpus was created as part of the Erasmus+ project "Transnation
Context. Multi-planet systems are important sources of information regarding the evolution of planets. However, the long-period planets in these systems often escape detection. These objects in particular may retain more of their primordial characteristics compared to close-in counterparts because of their increased distance from the host star. HD 22946 is a bright (G = 8.13 mag) late F-type star
Cross-section measurements for a Z boson produced in association with high-transverse-momentum jets (p T ≥ 100 GeV) and decaying into a charged-lepton pair (e + e − , μ + μ −) are presented. The measurements are performed using proton–proton collisions at s = 13 TeV corresponding to an integrated luminosity of 139 fb −1 collected by the ATLAS experiment at the LHC. Measurements of angular correlat
This entry describes the basic aspects of grounded theory method (GTM) and covers four key points. First, the goal of GTM is to generate a theory. Often the coding procedures are leveraged independently by researchers for data analysis, not to generate a theory. Second, the use of GTM implies a noncommittal literature review, where the emerging theory determines the relevance of that literature re
Background: Opioid-related overdose deaths remain a common cause of death in many settings, and opioid maintenance treatment is evidence-based for the treatment of opioid use disorders. However, access to such treatment varies and is limited in many settings. Methods: The present study examines the longitudinal effects of a regional patient choice reform which substantially increased availability
