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Finger jointing of freshly sawn Norway Spruce side boards : a comparative study of fracture properties of joints glued with phenol-resorcinol and one-component polyurethane adhesive

Finger jointing of unseasoned Norway Spruce was studied with respect to tensile strength, adhesive penetration and durability. Finger joints were manufactured with 1) unseasoned wood and one component polyurethane (PUR) adhesive, 2) dried wood and PUR adhesive and 3) dried wood and phenol resorcinol formaldehyde (PRF) adhesive. Two levels of wood density were used. The tensile strength of the fing

Review: The future of cell therapies and brain repair: Parkinson's disease leads the way.

During the past 40 years brain tissue grafting techniques have been used both to study fundamental neurobiological questions and to treat neurological diseases. Motor symptoms of Parkinson's disease are largely due to degeneration of midbrain dopamine neurones. Because the nigrostriatal pathology is relatively focused anatomically, Parkinson's disease is considered the ideal candidate for brain re

Radiological and clinical outcome of screw placement in adolescent idiopathic scoliosis: evaluation with low-dose computed tomography.

Posterior corrective surgery using "all pedicle screw construct" carries risk of neurovascular complications. The study aims were to assess the screw placement in patients with adolescent idiopathic scoliosis using CT with low-radiation dose, and to evaluate the clinical outcome in patients with misplaced pedicle screws. CTs of 49 consecutive patients (873 screws, 79% thoracic) were retrospectivel

Noncardiac Surgery in Patients With Aortic Stenosis: A Contemporary Study on Outcomes in a Matched Sample From the Danish Health Care System

BackgroundPast research has identified aortic stenosis (AS) as a major risk factor for adverse outcomes in noncardiac surgery; however, more contemporary studies have questioned the grave prognosis. To further our understanding of this, the risks of a 30-day major adverse cardiovascular event (MACE) and all-cause mortality were investigated in a contemporary Danish cohort. HypothesisAS is not an i

Integrative Genome and Transcriptome Analyses Reveal Two Distinct Types of Ring Chromosome in Soft Tissue Sarcomas.

Gene amplification is a common phenomenon in malignant neoplasms of all types. One mechanism behind increased gene copy number is the formation of ring chromosomes. Such structures are mitotically unstable and during tumor progression they accumulate material from many different parts of the genome. Hence, their content varies considerably between and within tumors. Partly due to this extensive va

Antibodies reactive to cleaved sites in complement proteins enable highly specific measurement of soluble markers of complement activation.

An emerging number of diseases and therapeutic approaches with defined involvement of the complement system justify a need for specific markers reflecting activation of particular effector arms of the complement cascade. Measurement of such soluble markers in circulation is a challenge since the specificity of antibodies must be limited to activated complement fragments but not predominant and ubi

Disintegration of the Top Stent on Zenith Abdominal Aortic Stent-Grafts.

PURPOSE: To describe a heretofore unreported complication involving the Zenith Low Profile (LP) stent-graft. CASE REPORT: Two men, aged 75 and 67 years, respectively, underwent abdominal aortic aneurysm repair with a Zenith LP device. At 4 and 3 years, respectively, computed tomography angiography revealed separation of the proximal fixation stent from the stent-graft. In the first patient, ther

Varisnp, A Benchmark Database For Variations from dbSNP.

For development and evaluation of methods for predicting the effects of variations, benchmark datasets are needed. Some previously developed datasets are available for this purpose, but newer and larger benchmark sets for benign variants have largely been missing. VariSNP datasets are selected from dbSNP. These subsets were filtered against disease-related variants in the ClinVar, UniProtKB/Swiss-

Non-contact acoustic capture of microparticles from small plasma volumes.

Microparticles (MP) are small (100-1000 nm) membrane vesicles shed by cells as a response to activation, stress or apoptosis. Platelet-derived MP (PMP) has been shown to reflect the pathophysiological processes of a range of cardiovascular diseases and there is a potential clinical value in using PMPs as biomarkers, as well as a need to better understand the biology of these vesicles. The current

Recovering from a Decade: A Systematic Mapping of Information Retrieval Approaches to Software Traceability

Engineers in large-scale software development have to manage large amounts of information, spread across many artifacts. Several researchers have proposed expressing retrieval of trace links among artifacts, i.e. trace recovery, as an Information Retrieval (IR) problem. The objective of this study is to produce a map of work on IR-based trace recovery, with a particular focus on previous evaluatio

The Neoarchaean Storø Supracrustal Belt, Nuuk region, southern West Greenland : an arc-related basin with continent-derived sedimentation

We present new major and trace element data, as well as Sm–Nd isotope compositions for Archaean supracrustal rocks and a gabbro-anorthosite complex from the island of Storø in Godthåbsfjord, southern West Greenland. We also provide new U–Pb isotope data for zircon extracted from these rocks. The Storø rocks have experienced amphibolite facies metamorphism, and the entire sequence forms an east-dip

Hospital costs for robot-assisted laparoscopic radical hysterectomy and pelvic lymphadenectomy.

OBJECTIVE: To compare robot-assisted laparoscopy and laparotomy for radical hysterectomy and pelvic lymphadenectomy in terms of hospital costs. METHODS: Consecutive women undergoing radical hysterectomy and pelvic lymphadenectomy as a sole procedure between January 2001 and February 2012 were included. We compared OR times, hospital stay, procedure specific costs, blood transfusions and cost for r

Identifying urban sources as cause of elevated grass pollen concentrations using GIS and remote sensing

We examine here the hypothesis that during flowering, the grass pollen concentrations at a specific site reflect the distribution of grass pollen sources within a few kilometres of this site. We perform this analysis on data from a measurement campaign in the city of Aarhus (Denmark) using three pollen traps and by comparing these observations with a novel inventory of grass pollen sources. The so

Adherence to the Mediterranean diet and risk of bladder cancer in the EPIC cohort study

There is growing evidence of the protective role of the Mediterranean diet (MD) on cancer. However, to date no epidemiological study has investigated the influence of the MD on bladder cancer. We evaluated the association between adherence to the MD and risk of urothelial cell bladder cancer (UCC), according to tumor aggressiveness, in the European Prospective Investigation into Cancer and Nutriti

Organizational discourse analysis - well done or too rare? A reply to our critics

In this article we respond to Bargiela-Chiappini, Iedema and Mumby.We notice that there is considerable agreement concerning the state of the art of organizational discourse analysis, while also discussing the disagreements. We expand on some of the ontological issues inherent in our argument, further discuss the character of reductionism in organizational discourse analysis, the trappings of a pr

Intratumorally implanted mesenchymal stromal cells potentiate peripheral immunotherapy against malignant rat gliomas.

Bone marrow-derived mesenchymal stromal cells (MSCs) target glioma extensions and micro-satellites efficiently when implanted intratumorally. Here, we report that intratumoral implantation of MSCs and peripheral immunotherapy with interferon-gamma (IFNγ) producing tumor cells improve the survival of glioma-bearing rats (54% cure rate) compared to MSC alone (0% cure rate) or immunotherapy alone (21

Endangered subspecies of the Reed Bunting (Emberiza schoeniclus witherbyi and E. s. lusitanica) in Iberian Peninsula have different genetic structures.

In the Iberian Peninsula, populations of two subspecies of the Reed Bunting Emberiza schoeniclus have become increasingly fragmented during the last decades when suitable habitats have been lost and/or the popula- tions have gone extinct. Presently, both subspecies are endangered. We estimated the amount of genetic variation and population structure in order to define conservation units and manage

Connect the Dots: Managing the Fragmentation of Global Climate Governance

The debate about post-2012 global climate governance has been framed largely by proponents and opponents of the policymaking process established by the United Nations Framework Convention on Climate Change (UNFCCC). In light of the proliferation of institutions governing some aspects of climate change, analysts have asked whether a centralized or a polycentric climate governance architecture will