Pushing the boundaries of acoustic particle separation: achieving high-throughput, avoiding spillover effects, investigating the effects of the particle concentration, and measuring acoustic properties
Acoustophoresis, i.e., the contactless manipulation of small cells or particles via acoustic waves is a gentle and label-free method that can, amongst others, be used to isolate rare cells such as circulating tumor cells from blood. To isolate enough cells, a large amount of sample needs to be processed in a reasonable amount of time. In a clinical setting, usually around 10 mL of blood can be col