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Background: Pelvic exenteration for locally recurrent rectal cancer (LRRC) is associated with variable outcomes, with the majority of data from single-centre series. This study analysed data from an international collaboration to determine robust parameters that could inform clinical decision-making. Methods: Anonymized data on patients who had pelvic exenteration for LRRC between 2004 and 2014 we
Due to its element and site specificity, inner-shell photoelectron spectroscopy is a widely used technique to probe the chemical structure of matter. Here, we show that time-resolved inner-shell photoelectron spectroscopy can be employed to observe ultrafast chemical reactions and the electronic response to the nuclear motion with high sensitivity. The ultraviolet dissociation of iodomethane (CH3I
β-Mannanases catalyze the conversion and modification of β-mannans and may, in addition to hydrolysis, also be capable of transglycosylation which can result in enzymatic synthesis of novel glycoconjugates. Using alcohols as glycosyl acceptors (alcoholysis), β-mannanases can potentially be used to synthesize alkyl glycosides, biodegradable surfactants, from renewable β-mannans. In this paper, we i
There has been widespread recognition in the Global South of the role of participatory governance approaches to urban development in responding to citizens’ immediate concerns. However, critiques note that participatory initiatives are often avenues for the political and economic elite to ensure their interests and profits, rather than improving the livelihoods in non- serviced urban peripheries.
In the pp→tt¯ process the angular distributions of top and anti-top quarks are expected to present a subtle difference, which could be enhanced by processes not included in the Standard Model. This Letter presents a measurement of the charge asymmetry in events where the top-quark pair is produced with a large invariant mass. The analysis is performed on 20.3 fb−1 of pp collision data at s=8TeV co
The purpose of this research is to explore how a stakeholder interaction perspective can add to the understanding of the dynamics of the process of corporate social responsibility (CSR) development in retail buyer–supplier relationships. Firstly, we find that interaction with suppliers and other stakeholders seems to have a pivotal role in the development towards sustainable retail supply chains.
This paper discusses various observations on beam-induced and cosmic-ray backgrounds in the ATLAS detector during the LHC 2012 proton-proton run. Building on published results based on 2011 data, the correlations between background and residual pressure of the beam vacuum are revisited. Ghost charge evolution over 2012 and its role for backgrounds are evaluated. New methods to monitor ghost charge
A system for local oscillator (LO) signal generation in 5G millimeter-wave (mmW) multi-antenna transceivers is presented. The system is modular with one phase locked loop (PLL) per antenna element transceiver, and a test circuit implemented in 28-nm fully depleted silicon on insulator (FD-SOI) CMOS features two such PLLs and a 491.52 MHz crystal oscillator (XO) generating a common frequency refere
Abstract: Cellulose gelation in 2 M NaOH aqueous solution was followed by time resolved turbidity and rheology measurements. The kinetics of gelation is observed to change from several hours down to few seconds when the temperature is increased from 25 to 30 °C. The increase of turbidity upon gelation demonstrates the formation of larger cellulose aggregates, while wide angle X-ray scattering data
To capture immediate cellular changes during diet-induced expansion of adipocyte cell volume and number, we characterized mature adipocytes during a short-term high-fat diet (HFD) intervention. Male C57BL6/J mice were fed chow diet, and then switched to HFD for 2, 4, 6 or 14 days. Systemic glucose clearance was assessed by glucose tolerance test. Adipose tissue was dissected for RNA-seq and cell s
Lack of reliable information on the status of species often leads managers to exclusively rely on experiential knowledge, opinions or perceptions, usually derived from personnel associated with natural resource management agencies. Yet, the accuracy of these sources of information remains largely untested. We approached this challenge, which is particularly common for wildlife monitoring programs
Surface rock fragments retard overland flow discharge, reduce the runoff generation rate and soil erosion as well as nutrients loss. In Northwest China, a common method for minimizing water, soil, and nutrient losses is the use of rock fragment cover. We used lab stimulation testing to evaluate rock fragment cover efficacy for nutrient conservation. Nutrient losses were determined in both the runo
Recent studies have raised concern that macrolide antibiotics may be associated with an increased long-term risk of cardiovascular death. We examined the 1-year risk associated with treatment with clarithromycin (n = 187,887) or roxithromycin (n = 698,899) compared with penicillin V (n = 3,473,081) matched 1:4 on propensity score, in a nationwide, registry-based cohort study in Danish outpatients,
Recension av Philipp Blom, Die Welt aus den Angeln
This paper demonstrates multiple-input-multiple-output (MIMO) throughput performance of a six-port dielectric resonator antenna (DRA) array for Wireless-LAN applications in a measured indoor office environment when a six-port dual-polarized patch array is used at the transmitter. The throughput was obtained using an IEEE802.11n/Draft 5.00 simulator for measured channels with different antenna and
In this paper, we study the potential benefits of downlink cooperative MIMO systems in cellular macrocell environments using a coherent measurement setup. Our results reveal that one of the two measured routes can leverage comparable signal strengths from the cooperating base stations to the mobile station and provide up to two-fold single user bitrate gain at the 50% cumulative probability level
This article reports on a search for dark matter pair production in association with a Higgs boson decaying to a pair of bottom quarks, using data from 20.3 fb-1 of pp collisions at a center-of-mass energy of 8 TeV collected by the ATLAS detector at the LHC. The decay of the Higgs boson is reconstructed as a high-momentum bb system with either a pair of small-radius jets, or a single large-radius
The identification of jets containing b hadrons is important for the physics programme of the ATLAS experiment at the Large Hadron Collider. Several algorithms to identify jets containing b hadrons are described, ranging from those based on the reconstruction of an inclusive secondary vertex or the presence of tracks with large impact parameters to combined tagging algorithms making use of multi-v
Background: Health-related quality of life (HRQoL) was a secondary end point in AGO-OVAR 16, which randomized 940 patients with EOC after first-line chemotherapy to maintenance pazopanib (PZ) or placebo (P). Additional post hoc analyses were carried out to investigate additional patient-centered end points. Patients and methods: HRQoL was measured with EORTC-QLQ-C30, QLQ-OV28 and EQ-5D-3L. Pre-spe
