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Extensive published evidence supports the use of subcutaneously-administered apomorphine as an effective therapy for Parkinson's disease (PD) but to date no consensus recommendations have been available to guide healthcare professionals in the optimal application of apomorphine therapy in clinical practice. This document outlines best-practice recommendations for selecting appropriate candidates f

A detailed investigation of the decomposition reactions and decay in the hydrogen storage capacity during repeated hydrogen release and uptake cycles for the reactive composite LiBH4-Al (2:3) is presented. Furthermore, the influence of a titanium boride, TiB2, additive is investigated. The study combines information from multiple techniques: in situ synchrotron radiation powder X-ray diffraction,

Neurodegenerative diseases can cause dysfunction of neural structures involved in judgment, executive function, emotional processing, sexual behavior, violence, and self-awareness. Such dysfunctions can lead to antisocial and criminal behavior that appears for the first time in the adult or middle-aged individual or even later in life.

Software breast phantoms are increasingly seeing use in preclinical validation of breast image acquisition systems and image analysis methods. Phantom realism has been proven sufficient for numerous specific validation tasks. A challenge is the generation of suitably realistic small-scale breast structures that could further improve the quality of phantom images. Power law noise follows the noise

A monatomic layer of graphite (MG or graphene) adsorbed on the (111) faces of transition metals Pt, Ir, and Ni, has been employed for controlling the atomic hydrogen adsorption site selectivity and the amount of hydrogen adsorbed upon saturation. The variations in the graphene-metal chemical bonding caused by hydrogenation and the values of saturated hydrogen coverage have been studied by X-ray ph

This paper presents an energy-efficient sorted QR decomposition (SQRD) processor for 3GPP LTE-Advanced (LTE-A) systems. The processor adopts a hybrid decomposition scheme to reduce computational complexity and provides a wide-range of performance complexity trade-offs. Based on the energy distribution of spatial channels, it switches between the brute-force SQRD and a low-complexity group-sort QR-

Islands of innovation as magnetic centres of star scientists? Empirical evidence on spatial concentration and mobility patterns, Regional Studies. Drawing on the results of a survey of 720 ‘star scientists’, this paper seeks to analyse the role of islands of innovation in the United States and Europe in providing educational and employment opportunities for such scientists and in attracting intern

PURPOSE A binational, population-based treatment protocol was established to prospectively treat and follow patients with seminomatous testicular cancer. The aim was to standardize care for all patients with seminoma to further improve the good results expected for this disease. PATIENTS AND METHODS From 2000 to 2006, a total of 1,384 Norwegian and Swedish patients were included in the study. Trea

Abstract Patients' satisfaction is an important outcome measure in reconstructive surgery and quality assurance is today central in the clinical practice. The aim of this study was to evaluate the patients' satisfaction with the process and final result after reconstruction for congenital microtia. A questionnaire was designed and sent to 78 patients who had undergone unilateral ear reconstruction

In the Simvastatin and Ezetimibe in Aortic Stenosis (SEAS) trial, combined ezetimibe (10 mg) and simvastatin (40 mg) decreased low-density lipoprotein cholesterol levels by 50% and ischemic cardiovascular event (ICE) risk by 22% compared to placebo. A larger decrease in ICE risk might have been expected for the degree of lipid-lowering observed. This analysis investigated relations between changes

Conditional cash transfers (CCTs) are often being promoted for their simultaneous advantages of short-term income protection and long-term human capital investments. Yet, existing evaluations have largely failed to test the underlying programme theory, and few empirical case studies have explored inherent contradictions and ambiguous consequences of this hybrid approach. To further understand the

Prior studies, utilizing interview-based assessments, suggest that most of the genetic risk factors for drug abuse (DA) are non-specific with a minority acting specifically on risk for abuse of particular psychoactive substance classes. We seek to replicate these findings using objective national registry data.

Nontypeable Haemophilus influenzae (NTHi) is one of the main aetiologies of childhood bacterial infections as well as exacerbations in COPD patients. Currently, no licensed NTHi vaccine exists. In the present study, we evaluated the potential of the conserved and ubiquitous surface protein Haemophilus Protein F (PF) as a vaccine candidate. Our results show that incubation of NTHi with anti-PF anti

The Precambrian inliers of the Anti Atlas belt located at the southern part of Morocco contain numerous mafic dyke and sill swarms thought to represent the erosional remnants of Proterozoic Large Igneous Provinces (LIPS). As part of a continuing research campaign to date and characterize these LIPs, four dykes have been dated by the U-Pb TIMS (Thermal Ionization Mass Spectrometry) method on baddel

We report a method for making horizontal wrap-gate nanowire transistors with up to four independently controllable wrap-gated segments. While the step up to two independent wrap-gates requires a major change in fabrication methodology, a key advantage to this new approach, and the horizontal orientation more generally, is that achieving more than two wrap-gate segments then requires no extra fabri

Histidine rich, unstructured peptides adsorb to charged interfaces such as mineral surfaces and microbial cell membranes. At a molecular level, we investigate the adsorption mechanism as a function of pH, salt, and multivalent ions showing that (1) proton charge fluctuations are - in contrast to the majority of proteins - optimal at neutral pH, promoting electrostatic interactions with anionic sur