This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To assess the efficacy and tolerability of pharmacological interventions for the treatment of CSWS and LKS.

A kinematically complete experiment on two-photon double ionization of Ar by free-electron laser radiation with a photon energy of 27.93 eV was performed. The electron energy spectra show that double ionization is dominated by the sequential process. Comparison of the electron angular distributions to our data for single ionization and to theory confirms that even in the sequential process the ele

Background: Mast cells may activate fibroblasts and contribute to remodeling processes in the lung. However, the mechanism behind these actions needs to be further investigated. Fibroblasts are major regulators of on-going remodeling processes. Protease activated receptor 2 (PAR2) expressed by fibroblasts may be activated by serine proteases, such as the mast cell mediator tryptase. The objective

Background: Idiopathic pulmonary fibrosis (IPF) is a fatal interstitial lung disease. Repetitive injury and reprogramming of the lung epithelium are thought to be critical drivers of disease progression, contributing to fibroblast activation, extracellular matrix remodeling, and subsequently loss of lung architecture and function. To date, Pirfenidone and Nintedanib are the only approved drugs kno

Large-scale genome-wide association studies (GWAS) have identified approximately 35 loci associated with epithelial ovarian cancer (EOC) risk. The majority of GWAS-identified disease susceptibility variants are located in noncoding regions, and causal genes underlying these associations remain largely unknown. Here, we performed a transcriptome-wide association study to search for novel genetic lo

Under the influence of neo-liberal ideals such as New Public Management, the ownership, operation, and maintenance of many Critical Infrastructures have been divided among an increasing number of public as well as private actors. Limited research has investigated the role of this institutional fragmentation for shaping resilience of Critical Infrastructures, especially in relation to recovery afteUnder the influence of neo-liberal ideals such as New Public Management, the ownership, operation, and maintenance of many Critical Infrastructures have been divided among an increasing number of public as well as private actors. Limited research has investigated the role of this institutional fragmentation for shaping resilience of Critical Infrastructures, especially in relation to recovery afte

In order to generate high-voltage high-pulsed power, klystron modulators necessarily contain at least one capacitor bank charging structure supplying the energy to be released during the pulse. Conventional charging structures are based on ac/dc front-end units typically based on diode rectifiers combined with power charging structures operated in on/off mode as a second stage, producing prohibiti

Background: Research suggests that humans have the tendency to increase the valence of events when these are imagined to happen in the future, but to decrease the valence when the same events are imagined to happen in the past. This line of research, however, has mostly been conducted by asking participants to value imagined, yet probable, events. Our aim was to re-examine this time-valence asymme

Like many other education systems in the world, Chinese education has undergone various reforms in order to adapt to the challenges that are perceived to emanate from the knowledge economy. Central to this transformation is the concept of ‘innovation’, which is to guide the country on its path from a production economy to a knowledge economy. Chinese policymakers have been targeting the higher edu

Using AlSb as the model system, we demonstrate that kinetic limitations can lead to the preferential growth of wurtzite (WZ) AlSb shells rather than the thermodynamically stable zinc-blende (ZB) AlSb and that the WZ and ZB relative thickness can be tuned by a careful control of the deposition parameters. We report selective heteroepitaxial radial growth of AlSb deposited by metal-organic vapor pha

This work presents experimental measurements of various 80 kWth propane flames, using a swirl burner, and modeling of the radiative heat transfer. The combustion conditions were altered by varying the oxygen concentration in the oxidant within range of 21-32%, while keeping the thermal input and oxygen-to-fuel ratio constant. Temperature, gas composition, and radiative intensity were measured usin

The stacking order of multilayer graphene significantly influences its electronic properties. The rhombohedral stacking sequence is predicted to introduce a flat band, which has high density of states and the enhanced Coulomb interaction between charge carriers, thus possibly resulting in superconductivity, fractional quantum Hall effect, and many other exotic phases of matter. In this work, we co

Natural hazards (i.e. earthquakes, floods) become disaster when they strike the man-made environment. To effectively reduce the impact of every disaster, governments prepare a complete strategy, called disaster management. Availability of data such as: buildings, lifeline systems, roads, hospitals and etc, will help the managers to better decision-making. The majority of this data is spatial and c

Emergency management requires precise and reliable information about the current situation of emergency, existing sources and facilities, while more than 80% of this information has spatial component or location. Considering the urgent and time sensitive nature of emergency situations, it is necessary to collect and use spatial information of the current state of the emergency within the minimum w

Tissue factor pathway inhibitor-2 (TFPI-2) has previously been characterized as an endogenous anticoagulant. TFPI-2 is expressed in the vast majority of cells, mainly secreted into the extracellular matrix. Recently we reported that EDC34, a C-terminal peptide derived from TFPI-2, exerts a broad antimicrobial activity. In the present study, we describe a previously unknown antimicrobial mode of ac

A decision is the result of comparing one or more alternatives with respect to one or more criteria that we consider relevant to the decision. Decision making can be considered as one of the most important challenges that analysts and experts encounter to solve complex problems. In recent decades, different methods and algorithms have been presented to support decision making. Multi-criteria analy