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Alterations in the human metabolome occur years before clinical manifestation of type 2 diabetes (T2DM). By contrast, there is little knowledge of how metabolite alterations in individuals with diabetes relate to risk of diabetes complications and premature mortality. Metabolite profiling was performed using liquid chromatography-mass spectrometry in 743 participants with T2DM from the population-

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We present a new experimental method that measures the compressibility of phenotype-specific cell populations. This is done by performing statistical analysis of the cell counts from the outlets of an acoustophoresis chip as a function of the increasing actuator voltage (i.e. acoustic energy density) during acoustophoretic separation. The theoretical separation performance curve, henceforth, Side-

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Tidigare publicerad i Skarhed, A., Hirschfeldt, J., Ruotsi, M., Westman, D. & Carlsson, S. (red.): Ord och rätt: Festskrift till Hans-Gunnar Axberger.

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The discovery, at the beginning of the 20th century, that elements can transform into other elements, due to the spontaneous decay of an instable to a stable atomic nuclei, gave rise to a powerful source for age information in many fields of earth science. For impact structures, it is crucial to establish well-defined and precise ages in order to understand how impact events affect the Earth’s geoThe discovery, at the beginning of the 20th century, that elements can transform into other elements, due to the spontaneous decay of an instable to a stable atomic nuclei, gave rise to a powerful source for age information in many fields of earth science. For impact structures, it is crucial to establish well-defined and precise ages in order to understand how impact events affect the Earth’s geo

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A characterisation is given of bounded embeddings from weighted L2 spaces on bounded intervals into L2 spaces on the half-plane, induced by isomorphisms given by the Laplace transform onto weighted Hardy and Bergman spaces (Zen spaces). As an application necessary and sufficient conditions are given for the boundedness of truncated Hankel and Toeplitz integral operators, including the weighted cas

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BibA, a group B streptococcus (GBS) surface protein, has been shown to protect the pathogen from phagocytic killing by sequestering a complement inhibitor: C4b-binding protein (C4BP). Here, the X-ray crystallographic structure of a GBS BibA fragment (BibA126-398) and a low-resolution small-angle X-ray scattering (SAXS) structure of the full-length N-terminal domain (BibA34-400) are described. The

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We present the first application of a new approach, proposed in (2016 J. Phys. G: Nucl. Part. Phys. 43 04LT01) to derive coupling constants of the Skyrme energy density functional (EDF) from ab initio Hamiltonian. By perturbing the ab initio Hamiltonian with several functional generators defining the Skyrme EDF, we create a set of metadata that is then used to constrain the coupling constants of t

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Serum vitamin D deficiency is widespread among older adults and is a potential modifiable risk factor for frailty. Moreover, frailty has been suggested as an intermediate step in the association between low levels of vitamin D and mortality. Hence, we conducted a systematic review of the literature and meta-analysis to test the possible association of low concentrations of serum 25-hydroxyvitamin

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Lärobok sjuksköterskeutbildningen

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Denna bok ger en integrerad framställning av de mestadels sakrättsliga aspekter som aktualiseras vid kreditgivning och finansiering, med särskilt fokus på realsäkerhetsfrågor.Boken inleds med en koncis översikt av ämnet sakrätt. Därefter följer presentationer av ägarförbehåll (återtagandeförbehåll) som kreditsäkerhet, olika slag av panträtt i lös egendom, fastighetspant och lagstiftningen om föret