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Comparison of predictive accuracy for pathologically organ confined clinical stage T1c prostate cancer using human glandular kallikrein 2 and prostate specific antigen combined with clinical stage and Gleason grade
Purpose: Previously human glandular kallikrein 2 (hK2) has been implicated to predict pathologically organ confined prostate cancer (PCa) in patients with stage T2 disease. Now we evaluated the usefulness of hK2, as measured by 2 entirely different immunoassay designs, to enhance the discrimination of pathologically organ from nonorgan confined clinical stage T1c PCa. Materials and Methods: A cons
Fascinating Fascism: Zhang Yimou's Hero (film review)
A review essay on Zhang Yimous film Hero and the critical reception.
Review of Purvis, Ole. W., Coppins, Brian, J., Hawksworth, David L. L., James, Peter, W. & Moore, D. M. (editors). The Lichen Flora of Great Britain and Ireland.
Abstract is not available
Exploring the actinide-actinide bond: Theoretical studies of the chemical bond in Ac-2, Th-2, Pa-2, and U-2
Multiconfigurational quantum chemical methods (CASSCF/CASPT2) have been used to study the chemical bond in the actinide diatoms Ac-2, Th-2, Pa-2, and U-2. Scalar relativistic effects and spin-orbit coupling have been included in the calculations. In the Ac-2 and Th-2 diatoms the atomic 6d, 7s, and 7p orbitals are the significant contributors to the bond, while for the two heavier diatoms, the 5f o
Intervention thresholds for osteoporosis in the UK
The aim of this study was to determine the threshold of fracture probability at which interventions became cost-effective in women based on data from the UK. We modelled the effects of an intervention costing pound350 per year given for 5 years that decreased the risk of all osteoporotic fractures by 35% followed by a waning of effect (offset time) for a further 5 years. Sensitivity analyses inclu
Regional cerebral blood flow in conscious stroke-prone spontaneously hypertensive rats
Regional cerebral blood flow (rCBF) was measured autoradiographically with [14C]iodoantipyrine as a diffusible tracer in two strains of conscious normotensive rats (Wistar Kyoto and local Wistar) and in two groups of spontaneously hypertensive stroke-prone rats (SHRSP) with a mean arterial pressure (MAP) below or above 200 mm Hg. In spite of the large differences in arterial pressure, rCBF did not
Ground-based measurements of tropospheric CO, C2H6, and HCN from Australia at 34 degrees S latitude during 1997-1998
High spectral resolution (0.004 cm(-1)) infrared solar absorption measurements Of CO, C2H6, and HCN have been recorded with the Fourier transform spectrometer located at the Network for the Detection of Stratospheric Change complementary station at the University of Wollongong, Australia (34.45 degreesS, 150.88 degreesE, 30 m above sea level). The time series covers March 1997 to February 1998. Pr
New Forms of Man-Machine Interaction
Randomised, placebo controlled trial of effect of a leukotriene receptor antagonist, montelukast, on tapering inhaled corticosteroids in asthmatic patients
OBJECTIVE: To determine the ability of montelukast, a leukotriene receptor antagonist, to allow tapering of inhaled corticosteroids in clinically stable asthmatic patients. DESIGN: Double blind, randomised, placebo controlled, parallel group study. After a single blind placebo run in period, during which (at most) two inhaled corticosteroids dose decreases occurred, qualifying, clinically stable p
The xanthophyll cycle, its regulation and components
During the last few years much interest has been focused on the photoprotective role of zeaxanthin. In excessive light zeaxanthin is rapidly formed in the xanthophyll cycle from violaxanthin, via the intermediate antheraxanthin, a reaction reversed in the dark. The role of zeaxanthin and the xanthophyll cycle in photoprotection, is based on fluorescence quenching measurements, and in many studies
Inclusive D-*+/- meson cross sections and D-*+/--jet correlations in photoproduction at HERA
Differential photoproduction cross sections are measured for events containing D-*+/- mesons. The data were taken with the H1 detector at the ep collider HERA and correspond to an integrated luminosity of 51.1 pb(-1). The kinematic region covers small photon virtualities Q(2) < 0.01 GeV2 and photon-proton centre-of-mass energies of 171 < W gamma(Cep) < 256 GeV. The details of the heavy quark produ
Lipopolysaccharide-induced down-regulation of uteroglobin in the human nose.
Conclusion. Lipopolysaccharide (LPS) challenge of the human nose has the capacity to reduce the amount of natural anti-inflammatory proteins, such as uteroglobin. Objectives. Nasal challenge with LPS, an activator of innate immunity, has been shown to increase the amount of pro-inflammatory mediators in nasal lavage fluid. Uteroglobin is a newly described anti-inflammatory mediator that is secrete
Expression, refolding and crystallization of Aquifex aeolicus elongation factor P.
Elongation factor P is a universally conserved protein stimulating peptidyltransferase activity during protein synthesis. The factor is sensitive to classical inhibitors of the ribosomal peptidyltransferase activity and is possibly involved in alignment of the substrate tRNAs in the catalytic centre of 70S ribosomes. Elongation factor P from the thermophilic Aquifex aeolicus was overexpressed as a
Betong för lagring av flytande naturgas : undersökning steg II : inverkan av mycket hög fuktnivå : inverkan av extremt låg temperatur, -196°C
Algal-bacterial processes for the treatment of hazardous contaminants: A review
Microalgae enhance the removal of nutrients, organic contaminants, heavy metals, and pathogens from domestic wastewater and furnish an interesting raw material for the production of high-value chemicals (algae metabolites) or biogas. Photosynthetic oxygen production also reduces the need for external aeration, which is especially advantageous for the treatment of hazardous pollutants that must be
Functional organization of climbing fibre projection to the cerebellar anterior lobe of the rat
1. The input characteristics and distribution of climbing fibre field potentials evoked by electrical stimulation of various parts of the skin were investigated in the cerebellum of barbiturate anaesthetized rats. 2. Climbing fibre responses were recorded in sagittally oriented microelectrode tracks across the mediolateral width of the anterior lobe. Climbing fibres with similar response latencies
Internal microdosimetry for single cells in radioimmunotherapy of B-cell lymphoma.
Moped and motorcycle accidents--similarities and discrepancies
Injury patterns and epidemiologic data from 211 moped accident victims and 214 motorcycle accident casualties admitted to hospital over a 5-year period (1977-1981) have been analyzed and compared. The number of those injured in motorcycle accidents tripled; the number of moped accident victims slightly decreased in the period studied. Differences in injury pattern, sex ratio, cause of accident, an
A general stability analysis of structural systems subjected to circulatory loading or thermal radiation in the elastic and elasto-plastic range
The paper examines the nonlinear behaviour of one- and two-degree-of-freedom discrete mechanical models subjected to partial follower load under conditions at which divergence instability occurs. Section (1.6) of the paper deals with the dynamic instability of an elastoplastic damped strut compressed by partial follower force at the free end. Space-time curves for the system are presented and disc
