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Reasons for action : making a difference to the security of outcomes

In this paper, we present a new account of teleological reasons, i.e. reasons to perform a particular action because of the outcomes it promotes. Our account gives the desired verdict in a number of difficult cases, including cases of overdetermination and non-threshold cases like Parfit’s famous Drops of water. The key to our account is to look more closely at the metaphysics of causation. Accord

Spectromicroscopic determinations of chemical environments of Ni in MoS2-Ag-Ni ternary systems

Using heterogeneous photocatalysts for harvesting sunlight and converting it for water remediation and splitting are promising to mitigate the possible crisis of environment and energy. Among various composites, the MoS2-based heterostructures and Ni-based systems exhibit unique electronic, optical properties and redox capabilities, enabling their roles as photocatalysts. Herein, the impacts of ch

Prolonged culture of human pancreatic islets under glucotoxic conditions changes their acute beta cell calcium and insulin secretion glucose response curves from sigmoid to bell-shaped

Aims/hypothesis: The rapid remission of type 2 diabetes by a diet very low in energy correlates with a marked improvement in glucose-stimulated insulin secretion (GSIS), emphasising the role of beta cell dysfunction in the early stages of the disease. In search of novel mechanisms of beta cell dysfunction after long-term exposure to mild to severe glucotoxic conditions, we extensively characterise

Navigating inclusion : ‘home-making’ in the UK Shin Buddhist community

This contribution focuses on narratives and experiences of belonging and exclusion among convert members of Three Wheels, a Japanese Shin Buddhist temple in London, to investigate how difference is incorporated into transnational Buddhism. Three Wheels, whose members include both diasporic Japanese and convert Buddhist Europeans, occupies a marginal position within both transnational Shin Buddhism

Long-Term Functional Outcome and Quality of Life After Surgical Evacuation of Spontaneous Supratentorial Intracerebral Hemorrhage : Results from a Swedish Nationwide Cohort

Objective: To investigate long-term survival, neurologic outcome, and quality of life in patients with spontaneous supratentorial intracerebral hemorrhage (ICH) treated with craniotomy and hematoma evacuation. Methods: A nationwide multicenter retrospective analysis of 341 patients who underwent craniotomy and evacuation of supratentorial ICH between January 1, 2011, and December 31, 2015, was per

Social work law in nexus with migration law : A legal cartographic analysis of inter-legal spaces of inclusion and exclusion in Swedish legislation

This article departs from the promise frequently put forward, that Social work is a profession committed to human rights. In a Swedish context, this commitment is manifested in ethical guidelines as well as national law referring to rights such as the right to ‘a reasonable living standard’. In recent years, politicized processes have allowed legislation guiding social work to interact deeply with

How does age affect outcomes after left ventricular assist device implantation : results from the PCHF-VAD registry

Aims: Use of left ventricular assist devices (LVADs) in older patients has increased, and assessing outcomes in older LVAD recipients is important. Therefore, this study aimed to investigate associations between age and outcomes after continuous-flow LVAD (cf-LVAD) implantation. Methods and results: Cf-LVAD patients from the multicentre European PCHF-VAD registry were included and categorized into

Polarisering : Idéhistoriska perspektiv på ett samtida fenomen

Mycket har sagts och skrivits om polarisering men sällan med några historiska tillbakablickar. Ibland kan det nästan framstå som att polarisering är ett helt nytt fenomen.I den här boken vänder åtta idéhistoriker på perspektivet och argumenterar för att företeelsen är lätt att finna även i det förgångna. Skribenterna ger oss inblickar i polariserade situationer och konflikter som

Area under the curve : Comparing the value of factor VIII replacement therapies in haemophilia A

Introduction: In factor VIII (FVIII) prophylaxis for haemophilia A, cost comparisons have used price per international unit (IU) based on the once reasonable assumption of equivalent outcome per IU. Now, with several extended half-life (EHL) products available, new outcome-oriented ways to compare products are needed. Area under the curve (AUC) quantifies FVIII levels over time after infusion prov

Examining the Use and Non-use of Special Transport Services in Sweden’s Large City-Regions: The Last Resort?

This study examines the extent of the gap between the proportions of survey respondents reporting (1) having the possibility to use and (2) using special transport services (STS) compared to the corresponding gaps for other transport modes. For persons eligible for STS, differences between those who use them and those who do not use them are explored. The frequencies with which these two groups le

Linking microenvironment modification to species interactions and demography in an alpine plant community

Individual plants can modify the microenvironment within their spatial neighborhood. However, the consequences of microenvironment modification for demography and species interactions remain unclear at the community scale. In a study of co-occurring alpine plants, we 1) determined the extent of species-specific microclimate modification by comparing temperature and soil moisture between vegetated

Risk of subsequent primary lymphoma in a cohort of 69,460 five-year survivors of childhood and adolescent cancer in Europe : The PanCareSurFup study

Background: Survivors of Hodgkin lymphoma (HL) are at risk of developing non-Hodgkin lymphoma (NHL) after treatment; however, the risks of developing subsequent primary lymphomas (SPLs), including HL and NHL, after different types of childhood cancer are unknown. The authors quantified the risk of SPLs using the largest cohort of childhood cancer survivors worldwide. Methods: The Pan-European Netw

Model-based screening for pancreatic cancer in Sweden

Background: Detecting pancreatic cancer at an earlier stage may contribute to an increased survival. Patients with stage I pancreatic cancer have a 5-year survival rate of 36%, while stage IV patients have a 5-year survival rate of 1% in Sweden. Research into novel blood-based biomarkers for pancreatic cancer is highly intensive and innovative, but has yet to result in any routine screening test.

Using Eye tracking technology to study digital writing processes.

This chapter presents an overview of eye tracking combined with tools for capturing digital writing (foremost keystroke logging). This includes a general rationale of why eye tracking is relevant for research on writing processes, how the technique works, and pros and cons of different eye trackers and methodological designs. The chapter describes previous L1 and L2 writing studies which have used

Using keystroke logging for studying L2 writing processes

This chapter presents an overview of keystroke logging. The chapter includes a general rationale for why and when the method is appropriate, how the technique works, and pros and cons with different methodological combinations of keystroke logging. Further, the chapter briefly outlines some previous L2 writing keystroke logging studies to illustrate the type of questions that can be addressed by t