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Monte Carlo simulations of a single polyelectrolyte in solution : Activity coefficients of the simple ions and application to viscosity measurements

Monte Carlo simulations of linear polyelectrolytes together with explicit ions have been performed in a spherical cell model to study conformational changes and activity coefficients in relation to the isoionic dilution method used in viscosity measurements. The results show that it is possible to define an effective ionic strength that will keep the average chain conformation constant on isoionic

Chain conformation and intermolecular interaction of partially neutralized poly(acrylic acid) in dilute aqueous solutions

The isoionic dilution method was used to measure the intrinsic viscosity, [η], and the Huggins coefficient, K(H), of two poly(acrylic acid) samples, 50% neutralized with NaOH, with molecular weights 5.0 x 103 (Na50PA5) and 4.8 x 104 (Na50PA48) at different ionic strengths. For Na50PA5 at low ionic strength, [η] is higher than the value predicted by a rigid-rod model. Assuming that the chain has re

Sense-Antisense lncRNA Pair Encoded by Locus 6p22.3 Determines Neuroblastoma Susceptibility via the USP36-CHD7-SOX9 Regulatory Axis

Trait-associated loci often map to genomic regions encoding long noncoding RNAs (lncRNAs), but the role of these lncRNAs in disease etiology is largely unexplored. We show that a pair of sense/antisense lncRNA (6p22lncRNAs) encoded by CASC15 and NBAT1 located at the neuroblastoma (NB) risk-associated 6p22.3 locus are tumor suppressors and show reduced expression in high-risk NBs. Loss of functiona

Increased synovial expression of nuclear receptors correlates with protection in pristane-induced arthritis: a possible novel genetically regulated homeostatic mechanism.

OBJECTIVE: To use microarray analyses of gene expression to characterize the synovial molecular pathways regulated by the arthritis regulatory locus Cia25 and to determine how it operates to control disease severity and joint damage.METHODS: Synovial tissues from DA rats and DA.ACI(Cia25) rats obtained 21 days after induction of pristane-induced arthritis were used for RNA extraction and hybridiza

Concealing or revealing? Alternative paths to profiting from innovation

According to the resource-based view, knowledge concealing is fundamental for firms’ ability to prevent competitor imitation and profit from innovation. Open innovation scholars have recently challenged this idea, proposing instead that knowledge revealing can foster industry-wide collaboration and enhance the value of innovation. Reconciling these two perspectives requires a more detailed underst

Successful outcome for patients with streptococcal prosthetic joint infections – a retrospective population-based study

Background/Aim: Streptococci cause approximately 10% of prosthetic joint infections (PJIs). The aim of this study was to identify the characteristics of patients with streptococcal PJIs and to describe the treatment and outcome of streptococcal PJIs in Skåne county between 2011 and 2015. Methods: Patients with streptococcal PJIs with positive cultures or PCRs on samples from joint aspirate and/or

An increasing number of hand injuries in an elderly population - A retrospective study over a 30-year period

Background: Both the number and the proportion of elderly people in the society increase. The number of elderly subjects with a disability due to a disease has decreased resulting in more active elderly. Therefore, an increase in numbers of injury in the elderly population can be expected; a hypothesis that was investigated in the present study. Methods: Two-hundred sixteen patients with an age of

The Long-Term Impact of Education on Mortality and Health: Evidence from Sweden

There is a well-documented large positive correlation between education and health and yet it remains unclear as to whether this is a causal relationship. Potential reasons for this lack of clarity include estimation using different methods, analysis of different populations and school reforms that are different in design. In this paper we assess whether the type of school reform, the instrument a

Primary Stenting of the Superficial Femoral Artery in Patients with Intermittent Claudication Has Durable Effects on Health-Related Quality of Life at 24 Months : Results of a Randomized Controlled Trial

Background: Intermittent claudication (IC) is commonly caused by lesions in the superficial femoral artery (SFA), yet invasive treatment is still controversial and longer term patient-reported outcomes are lacking. This prospective randomized trial assessed the 24-month impact of primary stenting with nitinol self-expanding stents compared to best medical treatment (BMT) alone in patients with sta

StanceXplore: Visualization for the Interactive Exploration of Stance in Social Media

The use of interactive visualization techniques in Digital Humanities research can be a useful addition when traditional automated machine learning techniques face difficulties, as is often the case with the exploration of large volumes of dynamic—and in many cases, noisy and conflicting—textual data from social media. Recently, the field of stance analysis has been moving from a predominantly bin

Miraklet Indien och dess baksida

Tio skandinaviska forskare med livslång erfarenhet av studier och forskning om Indien har skrivit originalartiklar kring sina specialområden såsom ekonomi, politik, kvinnofrågor, sociala förhållanden, kultur och religion. Boken söker sig under ytan av gängse Indienbilder och försöker förstå det moderna Indien i ett historiskt perspektiv som en del av en dynamik där också framtiden avtecknar sig.

Det man ser och inte ’ser’ - Indiens miljöutmaningar

Miljön hotas av förgiftning av luft, vatten och jordar. Industriutveckling och gruvdrift förstör miljön, liksom användningen av kol och bensin i de ständigt ökande transporter. Indiens möjligheter att komma till rätta med detta.

The 2005 Chios Ancient Shipwreck Survey : New Methods for Underwater Archaeology

In 2005 a Greek and American interdisciplinary team investigated two shipwrecks off the coast of Chios dating to the 4th-century b.c. and the 2nd/1st century. The project pioneered archaeological methods of precision acoustic, digital image, and chemical survey using an autonomous underwater vehicle (AUV) and in-situ sensors, increasing the speed of data acquisition while decreasing costs. The AUV

Why People Live in Flood-Prone Areas in Akuressa, Sri Lanka

To investigate why people live in areas at high risk of floods, a qualitative case study was carried out in the areas around Akuressa, in southwest Sri Lanka. Data col- lection consisted mainly of semistructured interviews with local residents and government officials. The purpose was to study why people live in areas at high risk of floods, by looking beyond the purely physical aspects of living

Enviro-organizational rift in Swedish flood risk governance

Floods tend not to be bounded by geopolitical or administrative borders, and involve various sectors in society. Flood risk must thus be jointly governed by a web of actors (Renn, 2008), who are not independent of each other but dependent on various resources and affected by the decisions and actions others are making (Becker, 2014). The patterns of social relations among these actors are therefor