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Transpeptidase activity of penicillin-binding protein SpoVD in peptidoglycan synthesis conditionally depends on the disulfide reductase StoA

Endospore cortex peptidoglycan synthesis is notrequired for bacterial growth but essential for endo-spore heat resistance. It therefore constitutes anamenable system for research on peptidoglycan bio-genesis. The Bacillus subtilis sporulation-specificclass B penicillin-binding protein (PBP) SpoVD andmany homologous PBPs contain two conserved cys-teine residues of unknown function in the transpepti

Directed Hamiltonicity and Out-Branchings via Generalized Laplacians

We are motivated by a tantalizing open question in exact algorithms: can we detect whether an n-vertex directed graph G has a Hamiltonian cycle in time significantly less than 2^n? We present new randomized algorithms that improve upon several previous works: 1. We show that for any constant 0

The carboxin-binding site on Paracoccus denitrificans succinate:quinone reductase identified by mutation and structure comparison

Succinate:quinone reductase catalyzes electron transfer from succinate to quinone in aerobic respiration. Carboxin is a specific inhibitor of this enzyme from several different organisms. We have isolated mutant strains of the bacterium Paracoccus denitrificans that are resistant to carboxin due to mutations in the succinate:quinone reductase. The mutations identify two amino acid residues, His228

The forest as a taskscape: seeing through the good forest owner’s eyes

This article is a reanalysis of interviews conducted in 2006 and 2009 with forest owners and their families. It gives a complementary interpretation of the forest owners’ decisions to replant spruce despite strong criticism from the public and from experts. The interviewees’ visual conception of the forest landscape and how they relate to it through their forestry practices is analysed. The result

Cramer-Rao Lower Bounds for Positioning with Large Intelligent Surfaces

We consider the potential for positioning with a system where antenna arrays are deployed as a large intelligent surface (LIS). We derive Fisher-informations and Cram\'{e}r-Rao lower bounds (CRLB) in closed-form for terminals along the central perpendicular line (CPL) of the LIS for all three Cartesian dimensions. For terminals at positions other than the CPL, closed-form expressions for the Fishe