Hypoxia, or deficient oxygen levels, is an inherent feature of rapidly expanding tumor tissue. In order to survive in the hostile, hypoxic environment and to restore the supply of oxygen and nutrients tumor cells activate a variety of adaptive mechanisms. Among them, hypoxia-induced angiogenesis, i.e. the formation of tumor blood vessels from pre-existing vasculature, has proved to be of critical

Popular Abstract in Swedish Tack vare den snabba tekniska och digitala utvecklingen under senare år har tomosyntes etablerats som ett nytt och spännande verktyg inom röntgendiagnostiken. Metoden är en vidareutveckling av gammaldags tomografi (skiktröntgen), men är lättare att utföra, ger bättre bilder och dessutom är stråldosen betydligt lägre. Vid tomosyntes gör röntgenröret ett svep över den krThe aims of this thesis were to investigate whether chest tomosynthesis might be used in pulmonary cystic fibrosis, to design and validate a tomosynthesis scoring system, and to determine the effective dose from chest tomosynthesis in children. In a prospective study starting in 2008 clinical chest radiography or computed tomography (CT) were supplemented with a tomosynthesis examination of the l

Abstract in Undetermined In this paper, the news aggregator GoogleNews is used to assess the impact ofworldwide news on the volatility of the Chinese stock market. Although we find a strong link between the global stock market volatility and the amount of stock market-related news available worldwide, the link between the Chinese stock market and the same set of worldwide news is found to be much

Ordered nanoporous structures are among the most fascinating and industrially important materials currently in use. The archetypal zeolite material has now been joined by an eclectic array of new structures that exhibit porosity over a wide range of length scales and with order/disorder expressed in a multitude of ways. This raises the bar in terms of characterization and extends a real challenge

We present RF characterization of vertical gateall- around InAs nanowire MOSFETs integrated on Si substrates with peak f(t) = 142 GHz and f(max) = 155 GHz, representing the record for vertical nanowire transistors. The devices has an L-g approximate to 150 nm with a g(m)=700 mS/mm for a nanowire diameter of 38 nm and an EOT = 1.4 nm. The high values of f(t) is achieved through electron beam lithog

Measurements of differential cross sections for J/psi production in p + Pb collisions at root S-NN= 5.02 TeV at the CERN Large Hadron Collider with the ATLAS detector are presented. The data set used corresponds to an integrated luminosity of 28.1 nb(-1). The J/psi mesons are reconstructed in the dimuon decay channel over the transverse momentum range 8 < PT < 30 GeV and over the center-of-mass ra

Measurements with unknown time delays are common in different applications such as microphone array, radio antenna array calibration, where the sources (e.g. sounds) are transmitted in unknown time instants. In this paper, we present a method for estimating unknown time delays from Time-Difference-of-Arrival (TDOA) measurements. We propose a novel rank constraint on a matrix depending on the measu

Recent advances in live imaging and genetics of mammalian development which integrate observations of biochemical activity, cell-cell signaling and mechanical interactions between cells pave the way for predictive mathematical multi-scale modeling. In early mammalian embryo development, two of the most critical events which lead to tissue patterning involve changes in gene expression as well as me

A method for determination of polycyclic aromatic hydrocarbons (PAHs) from aerosols was developed. Instead of conventionally used non-polar or slightly polar phenylmethylpolysiloxane column a highly polar, highly substituted, cyanopropyl column (VF-23 MS) was used for separation of PAHs. Based on hollow fiber micro-porous membrane liquid-liquid extraction (HF-MMLLE) a method was developed for samp

We have investigated the structure and morphology of the InAs(1 1 1)B surface using Low Energy Electron Diffraction (LEED), Scanning Tunneling Microscopy (STM) and Scanning Electron Microscopy (SEM). The surface was prepared by annealing in the presence of an arsenic or atomic hydrogen pressure. A (2 x 2) reconstruction that changes into a (1 x 1) unreconstructed surface after prolonged annealing

The nature of solid-solid phase transformations has been a long-standing question spanning the fields of metallurgy and condensed-matter physics, with applications from metallic alloys and ceramics to modern shape-memory materials. In spite of the importance of solid-to-solid transformations in many areas of materials science and condensed-matter physics and the numerous experimental and theoretic

Recension av Jonathan Brent; Stalins arkiv. Sökandet efter det Nya Ryssland.

Background: Public transport is low cost, allows for independence, and facilitates engagement and participation for non-drivers. However, the viewpoints of individuals with cognitive disabilities are rarely considered. In Australia, the prevalence of Autism Spectrum Disorders (ASD) is approximately 1% and increasing. Many individuals with ASD do not possess a driver's licence, indicating that acce

Objective - Disturbances in hippocampal neurogenesis may be involved in the pathophysiology of depression and it has been argued that an increase in the generation of new nerve cells in the hippocampus is involved in the mechanism of action of antidepressants. Materials and Methods - Adult Wistar rats were treated with fluoxetine (10 mg/kg) 1 h, daily for 5 (subchronic) or 28 days (chronic) before

This article discusses the concept of planetary boundaries that has been advanced by a group of leading experts around Johan Rockstrom. I place the concept of planetary boundaries in the larger framework of the emerging research paradigm of earth system governance, welcoming it as a crucial contribution that defines the overall goals of governance. Yet I also elaborate on the political conflicts t

This study examined how root growth and morphology were affected by variation in soil moisture at four Amazon rainforest sites with contrasting vegetation and soil types. Mean annual site root mass, length and surface area growth ranged between 3-7 t ha(-1), 2-4 km m(-2) and 8-12 m(2) m(-2) respectively. Mean site specific root length and surface area varied between 8-10 km kg(-1) stop and 24-34 m

Food with inputs from genetically modified organisms (GMOs) has met considerable skepticism among European Union (EU) consumers. The EU import ban on GM food has triggered a great deal of controversy and has been partly replaced by a mandatory labeling scheme. Although there is no measure in the General Agreement on Tariffs and Trade that directly addresses the use of product labeling, WTO and oth

The objective of this work was to examine the atazanavir-bilirubin relationship using a population-based approach and to assess the possible application of bilirubin as a readily available marker of atazanavir exposure. A model of atazanavir exposure and its concentration-dependent effect on bilirubin levels was developed based on 200 atazanavir and 361 bilirubin samples from 82 patients receiving