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AIM: To describe further functional deficiencies of neonatal neutrophils by measuring the expression of C5a receptors.METHODS: C5a uptake was measured using flow cytometry with fluorescein isothiocynate labelled recombinant C5a. The response of neutrophils to stimulation with C5a and fMLP was tested by measuring migration and exocytosis of myeloperoxidase and lactoferrin.RESULTS: C5a mean fluoresc
President Donald Trump’s “America First” policy questions the fundamentals of the global U.S.-led alliance network. Where other allies implemented hedging strategies, Japan’s Prime Minister Abe Shinzō pledged to “make the alliance even greater,” insisting that the bilateral ties were “airtight” and “stronger than ever before.” However, Trump’s approach to trade, détente with North Korea, and off-t
This paper presents isolated photon-hadron correlations using pp and p-Pb data collected by the ALICE detector at the LHC. For photons with |η|
In this Letter, we report the first measurement of the inelastic cross section for antideuteron-nucleus interactions at low particle momenta, covering a range of 0.3≤p
Our knowledge of the intestinal immune system of fish is rather limited compared to mammals. Very little is known about the immune cells including the phagocytic cells in fish intestine. Hence, employing imaging flow cytometry and RNA sequencing, we studied adherent cells isolated from healthy Atlantic salmon. Phagocytic activity and selected gene expression of adherent cells from the distal intes
Heterozygotes for major chromosomal rearrangements such as fusions and fissions are expected to display a high level of sterility due to problems during meiosis. However, some species, especially plants and animals with holocentric chromosomes, are known to tolerate chromosomal heterozygosity even for multiple rearrangements. Here, we studied male meiotic chromosome behavior in four hybrid generat
Trä som byggnadsmaterial används till allt från trädäck och möbler till broar och höghus. Enbart i Sverige används 5-6 miljoner m3 sågade barrträvaror årligen varav ungefär hälften används i byggtillämpningar [2]. Till bärande konstruktioner inom hus- och brobyggnad nyttjas framförallt gran och furu men för trädäck och träpanel finns det en uppsjö av olika träslag och behandlingar på marknaden. Vi
Recently, intense research activities have been focused on solution-processed hybrid lead halide perovskite semiconductors which are being developed for the solar-cell, light emitting diode (LED), and lasing applications. To optimize and fabricate a competitive perovskite-based optoelectronic device, the fundamental studies of the electronic structure, photo-generated carrier dynamics as well as t
Many scholars have regarded China's emergence as an economic force as a threat to democracy in Africa, presenting China as the exporter of an authoritarian model through its rising economic influence. This article investigates how well founded the contended Chinese economic threat to Africa is by both analyzing the data at a very fundamental level and applying time-series, cross-sectional analysis
Root exudates are a labile source of carbon (C) for microorganisms that can lead to increased CO2 emission. Root exudates can vary in C:N stoichiometric ratio and their impact on microbially driven soil organic matter (SOM) turnover in paddy soils still remains unclear. The objective was to explore the underlying mechanisms involved in SOM decomposition due to root exudate (artificial) addition wi
HSC aging is clinically associated with risk of anemia, immune compromise, and malignancy. Mansell et al. show that mitochondrial activity is directly linked to age-related performance of HSCs and that its perturbation has direct consequences for HSC function, resulting in alleviation or prevention of hematopoietic aging.
In order to achieve nominal performance in terms of the dynamic aperture and lifetime of a storage ring, it is important to be able to characterise and correct its second order optics. At the MAX IV 3 GeV storage ring in Lund, Sweden, the linearity of the 2nd order dispersion with chromatic sextupole field strengths has been utilised to investigate the sextupole circuits. The beating induced in th
Ovarian clear cell carcinomas (OCCC) constitute a rare subtype of epithelial ovarian cancer, lacking efficient treatment options. Based on previous studies, we assessed the anti-proliferative effect of simvastatin, a Rho GTPase interfering drug, in three OCCC cell lines: JHOC-5, OVMANA and TOV-21G, and one high-grade serous ovarian cancer (HGSOC) cell line, Caov3. We used the Rho GTPase interferin
Significant advances have been made towards understanding the role of immune cell-tumor interplay in either suppressing or promoting tumor growth, progression, and recurrence, however, the roles of additional stromal elements, cell types and/or cell states remain ill-defined. The overarching goal of this NCI-sponsored workshop was to highlight and integrate the critical functions of non-immune str
Neurofilaments are structural components of neurons and are particularly abundant in highly myelinated axons. The levels of neurofilament light chain (NfL) in both cerebrospinal fluid (CSF) and plasma have been related to degeneration in several neurodegenerative conditions including frontotemporal dementia (FTD) and NfL is currently considered as the most promising diagnostic and prognostic fluid
We present a simple technique to experimentally determine the optical-path length change with temperature for optical single-mode fibers. Standard single-mode fibers act as natural low-finesse cavities, with the Fresnel reflection of the straight cleaved surfaces being ∼3%, for the laser light coupled to them. By measuring the intensity variations due to interference of light reflected from the fi
We provide bibliographical connections and extensions of several representations of the classical Laplace distribution, discussed recently in the study of Ding and Blitzstein. Beyond presenting relation to some previous results, we also include their skew as well as multivariate versions. In particular, the distribution of det Z, where Z is an n × n matrix of iid standard normal components, is obt
