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Retinitis Pigmentosa involves a hereditary degeneration of photoreceptors by as yet unresolved mechanisms. The secretable protein α-Klotho has a function related to ageing processes, and α-Klotho deficient mice have reduced lifespan and declining functions in several tissues. Here, we studied Klotho in connection with inherited photoreceptor degeneration. Increased nuclear immunostaining for α-Klo
Dopamine (DA) replacement therapy with l-DOPA remains the most effective treatment for Parkinson's disease, but causes dyskinesia (abnormal involuntary movements) in the vast majority of the patients. The basic mechanisms of l-DOPA-induced dyskinesia (LID) have become the object of intense research focusing on neurochemical and molecular adaptations in the striatum. Here we review this vast litera
Two constructions of binary concatenated convolutional codes are considered. In our previous work [Proc. 4th Int. Symp. Commun. Theory Appl., Lake District, UK (1997)] such codes were called woven convolutional codes. In the present paper, asymptotic lower bounds on active distances of woven convolutional codes are investigated. It is shown that these distances can be bounded from below by linearl
Om politiska historiebruk och viljan att använde det förflutna för dagspolitiska syften.
Software for recognition of handwriting has been available for several decades now and research on the subject have produced several different strategies for producing competitive recognition accuracies, especially in the case of isolated single characters. The problem of recognizing samples of handwriting with arbitrary connections between constituent characters (emph{unconstrained handwriting})
Roads and pavements covered with ice and snow during winter in the Nordic and other cold regions are slippery, which result in the prevalence of slip and fall accidents among not only the public, but also outdoor workers. Literature and injury statistics revealed that the most frequently specified contributory factor for occupational slip, trip and fall accidents in Sweden is snow and ice. Road ac
White matter (WM) changes are frequently seen on structural imaging in AD but the clinical relevance of these changes is uncertain. Frontal WM pathology is often observed upon neuropathological examination in AD. Since frontal cortical/sub-cortical pathology is known to relate to executive dysfunction, the aim was to elucidate if frontal WM changes in AD correlated with executive dysfunction. In a
