Acute effects of D-1 and D-2-receptor agonist and antagonist drugs on somatostatin binding, inhibition of adenylyl cyclase activity and accumulation of inositol 1,4,5-trisphosphate in the rat striatum
A recent study carried out by our group demonstrated that exogenous dopamine increases the somatostatin (SS) receptor–effector system in the rat striatum. The present study examined the participation of the D1- and D2-dopaminergic systems in the modulation of the rat striatal SS receptor–effector system by use of the D1-receptor agonist and antagonist SKF 38393 and SCH 23390, respectively, and the
