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Developmental plasticity in reptiles: Insights from temperature-dependent gene expression in wall lizard embryos : Insights from temperature-dependent gene expression in wall lizard embryos

Many features of the development of reptiles are affected by temperature, but very little is known about how incubation temperature affects gene expression. Here, we provide a detailed case study of gene expression profiles in common wall lizard (Podarcis muralis) embryos developing at stressfully low (15°C) versus benign (24°C) temperature. For maximum comparability between the two temperature re

Airway physical examination tests for detection of difficult airway management in apparently normal adult patients

Background: The unanticipated difficult airway is a potentially life-threatening event during anaesthesia or acute conditions. An unsuccessfully managed upper airway is associated with serious morbidity and mortality. Several bedside screening tests are used in clinical practice to identify those at high risk of difficult airway. Their accuracy and benefit however, remains unclear. Objectives: The

Asymptotically Optimal Regression Trees

Regression trees are evaluated with respect to mean square error (MSE), mean integrated square error (MISE), and integrated squared error (ISE), as the size of the training sample goes to infinity. The asymptotically MSE- and MISE minimizing (locally adaptive) regression trees are characterized. Under an optimal tree, MSE is O(n^{-2/3}). The estimator is shown to be asymptotically normally distrib

Human igg increases virulence of streptococcus pyogenes through complement evasion

Streptococcus pyogenes is an exclusively human pathogen that can provoke mild skin and throat infections but can also cause fatal septicemia. This gram-positive bacterium has developed several strategies to evade the human immune system, enabling S. pyogenes to survive in the host. These strategies include recruiting several human plasma proteins, such as the complement inhibitor, C4b-binding prot

Soil solution electrical conductivity measurements under transient conditions using Time Domain Reflectometry

Several studies have shown that time domain reflectometry (TDR) can be used to measure water content and solute concentration during steady-state experiments with constant soil water content. Few studies have been carried out to identify the relationship between bulk electrical conductivity (σa) and soil solution electrical conductivity (σw) to be used for transient conditions with varying water c

A genome-wide association study of IgM antibody against phosphorylcholine : Shared genetics and phenotypic relationship to chronic lymphocytic leukemia

Phosphorylcholine (PC) is an epitope on oxidized low-density lipoprotein (oxLDL), apoptotic cells and several pathogens like Streptococcus pneumoniae. Immunoglobulin M against PC (IgM anti-PC) has the ability to inhibit uptake of oxLDL by macrophages and increase clearance of apoptotic cells. From our genome-wide association studies (GWASs) in four Europeanancestry cohorts, six single nucleotide p

Collective Incentives and Cooperation in Teams with Imperfect Monitoring

We experimentally explore the role of collective incentives in sustaining cooperation in finitely repeated public goods games with imperfect monitoring. In our experiment players only observe noisy signals about individual contributions, while total output is perfectly observed. We consider sanctioning mechanisms that allow agents to commit to collective punishment in case total output fall short

Linguistic landscaping in Singapore : multilingualism or the dominance of English and its dual identity in the local linguistic ecology?

Although Singapore, a linguistically and ethnically diverse city–state, uses four official languages, namely Malay, Mandarin, Tamil, and English, which are supposed to enjoy equal status, there appears to be a pecking order to these languages. English seems to be the dominant language when taking into consideration the bilingual education policy, numerous campaigns promoting its use in terms of sp

Impact of Rye Kernel-Based Evening Meal on Microbiota Composition of Young Healthy Lean Volunteers With an Emphasis on Their Hormonal and Appetite Regulations, and Blood Levels of Brain-Derived Neurotrophic Factor

Rye kernel bread (RKB) evening meals improve glucose tolerance, enhance appetite regulation and increase satiety in healthy volunteers. These beneficial effects on metabolic responses have been shown to be associated with increased gut fermentation. The present study aimed to elucidate if RKB evening meals may cause rapid alterations in microbiota composition that might be linked to metabolic-, im

Pedagogik som vetenskap. En inbjudan.

Pedagogik är en av de klassiska vetenskapliga disciplinerna och har som universitetsämne en hundraårig tradition. I takt med att samhället förändras har även det innehåll som sysselsätter pedagogiken ändrats. Var befinner sig det vetenskapliga ämnet pedagogik i dag? Hur ser den historiska bakgrunden till ämnets framväxt ut? Vilka är de fundament som håller samman pedagogikämnet? Vilka framtida utm

Validation of Phase Contrast Flow Quantification and Relaxometry for Cardiovascular Magnetic Resonance Imaging

Quantitative imaging, where every pixel of an image represents a physical quantity (e.g. timeor velocity) is being increasingly used in the field of diagnostic radiology and has potential toenhance medical diagnosis. Quantitative methods for Magnetic Resonance Imaging (MRI)enables measurements of velocity and flow using a technique called Phase Contrast MagneticResonance (PC-MR), and different tim

Texture and electrical conductivity effects on temperature dependency in time domain reflectometry

If not accounted for, temperature effects on the water content and electrical conductivity measured with time domain reflectometry (TDR) will introduce significant errors. In this study, an automated TDR system was used to quantify the temperature dependence of the apparent dielectric constant and electrical conductivity in wet soils. Sandy, clayey, and organic soils were used to examine the effec

Children as co-creators? : The limits of the concept of service dominant logic for public welfare services targeting children

Co-creation (or co-production, Voorberg et al., 2015) of public services together with individual service users is based on the assumption that the individual can define her or his own value to be co-created. However, in the case of children, this can be put into doubt, as children do not have the same cognitive perspectives and abilities as adults, and a weaker voice as agents. This results in thCo-creation (or co-production, Voorberg et al., 2015) of public services together with individual service users is based on the assumption that the individual can define her or his own value to be co-created. However, in the case of children, this can be put into doubt, as children do not have the same cognitive perspectives and abilities as adults, and a weaker voice as agents. This results in th

Characterization of Irreversible Fouling after Ultrafiltration of Thermomechanical Pulp Mill Process Water

Large volumes of wastewater with dissolved wood components are treated in wastewater treatment plants at thermomechanical pulp mills. It has been shown previously that hemicelluloses in these wastewater streams can be recovered by membrane filtration. A serious obstacle when treating lignocellulose process streams is fouling of the membranes. Fouling not only increases operating costs but also red