Sökresultat

Filtyp

Din sökning på "*" gav 534403 sökträffar

Search for lepton-flavor-violating decays of the Z boson into a τ lepton and a light lepton with the ATLAS detector

Direct searches for lepton flavor violation in decays of the Z boson with the ATLAS detector at the LHC are presented. Decays of the Z boson into an electron or muon and a hadronically decaying τ lepton are considered. The searches are based on a data sample of proton-proton collisions collected by the ATLAS detector in 2015 and 2016, corresponding to an integrated luminosity of 36.1 fb-1 at a cen

Polygenic Risk Score for Coronary Heart Disease Modifies the Elevated Risk by Cigarette Smoking for Disease Incidence

BACKGROUND: Coronary heart disease (CHD) is a multifactorial disease with both genetic and environmental components. Smoking is the most important modifiable risk factor for CHD. Our aim was to test whether the increased CHD incidence by smoking is modified by genetic predisposition to CHD. METHODS AND RESULTS: Our study included 24 443 individuals from the MDCS (Malmö Diet and Cancer Study). A we

MiRNA and other non-coding RNAs as promising diagnostic markers

Since the discovery of non-coding RNAs (ncRNAs) a new area has emerged in the field of biomarkers. NcRNAs are RNA molecules of different sizes that are transcribed as independent genes or as part of protein coding genes and are not translated, therefore they do not produce proteins. They have been classified accord-ing to their size and function and include micro RNAs (miRNAs), piwiRNAs (piRNAs),

Housing accessibility and participation among older adults with long-standing spinal cord injury

En stödjande miljö är centralt för att kunna upprätthålla ett självständigt liv och effektivt aktivitetsutförande, särskilt med ökande ålder. För personer med funktionella begränsningar, som konsekvenserna av en ryggmärgsskada, är balansen mellan personens funktionella kapacitet och miljöns krav av yttersta vikt för att kunna leva ett så välfungerande liv som möjligt. Livslängden efter en ryggmärg

Reduced kinetic mechanism for methanol combustion in spark-ignition engines

A reduced kinetic mechanism for methanol combustion at spark-ignition (SI) engine conditions is presented. The mechanism consists of 18 species and 55 irreversible reactions, small enough to be suitable for large eddy simulations (LES). The mechanism was reduced and optimized using the comprehensive mechanism (AramcoMech 2.0) as a starting point, to maintain performance at stoichiometric condition

Understanding practical challenges to risk and vulnerability assessments : the case of Swedish municipalities

Assessing risks and vulnerabilities in the multifaceted context of a municipality is challenging. There is a plethora of methods and tools to support this task. However, to achieve successful outcomes from Risk and Vulnerability Assessments (RVAs), merely applying theoretically and technically rigorous methods is far from enough; the question of how a method is implemented in a practical context i

Search for chargino-neutralino production using recursive jigsaw reconstruction in final states with two or three charged leptons in proton-proton collisions at s =13 TeV with the ATLAS detector

A search for electroweak production of supersymmetric particles is performed in two-lepton and three-lepton final states using recursive jigsaw reconstruction, a technique that assigns reconstructed objects to the most probable hemispheres of the decay trees, allowing one to construct tailored kinematic variables to separate the signal and background. The search uses data collected in 2015 and 201

The Fiat-Shamir Zoo : Relating the Security of Different Signature Variants

The Fiat-Shamir paradigm encompasses many different ways of turning a given identification scheme into a signature scheme. Security proofs pertain sometimes to one variant, sometimes to another. We systematically study three variants that we call the challenge (signature is challenge and response), commit (signature is commitment and response), and transcript (signature is challenge, commitment an

Particles with tunable wettability for solid-stabilized emulsions

We demonstrate that the wettability of cosmetic grade, silica-coated titanium dioxide nanoparticles may be tuned by simply soaking them in a cyclic silicone oil. This allows for tuning the type of emulsion that they stabilize, from oil-in-water to water-in-oil. By analyzing the sedimentation of water-in-oil emulsions, the effect of the soaking time (wettability) on drop size and drop-drop interact

Improvement of thermotolerance in Lachancea thermotolerans using a bacterial selection pressure

The use of thermotolerant yeast strains is an important attribute for a cost-effective high temperature biofermentation processes. However, the availability of thermotolerant yeast strains remains a major challenge. Isolation of temperature resistant strains from extreme environments or the improvements of current strains are two major strategies known to date. We hypothesised that bacteria are po

No title

Influence of sintering temperature on both phase composition and structure of ceramic matrix composites based on cubic boron nitride with binders in a form of Al and the Ti, Cr, V carbides are investigated by methods of physical materials science. As the object of study, three cBN–TiC–Al, cBN–Cr3C2–Al, cBN–VC–Al compositions containing 60% vol. cBN are selected. The composites are obtained by high

Clonal evolution through genetic bottlenecks and telomere attrition : Potential threats to in vitro data reproducibility

Tissue cultures of immortalized human cells, also known as established cell lines, are broadly accessible and cost-efficient tools for biomedical research. We here review potential genetic sources of systematic error in cell line experiments due to clonal evolution in vitro. In particular, the authors highlight alterations in telomere function over prolonged culture and population bottlenecks, res

Targeting peptidylarginine deiminase reduces neutrophil extracellular trap formation and tissue injury in severe acute pancreatitis

Recent evidence suggests that neutrophil extracellular traps (NETs) play an important role in the development of acute pancreatitis (AP). Herein, we examined the role of peptidylarginine deiminase (PAD), which has been shown to regulate NET formation, in severe AP. AP was induced by retrograde of taurocholate infusion into pancreatic duct in C57BL/6 mice. PAD was pharmacologically inhibited using