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The increase of plasma levels of high-density lipoproteins and Apolipoprotein A-I (ApoA-I), its main protein component, has been shown to have a positive action on glucose disposal in type 2 diabetic patients. The current study investigates the unexplored function of ApoA-I to prime beta cells for improved insulin secretion. INS-1E rat clonal beta cells as well as isolated murine islets were used
In this paper we analyse the transmission of the electromagnetic field through a dielectric, spherical shell - a simple radome. The source is located inside the shell and consists of a vertical or horizontal electric dipole or a simple array of electric dipoles. A circular PEC (perfect electric conductor) disk is located at the center of the shell and simulates a ground plane. The effect of the sh
Knäleden är kroppens största led och är påtagligt komplicerad. Den utsätts dagligen för stora krafter vid såväl böj och vridrörelser som stötkrafter vid stegisättning. För att den skall fungera optimalt måste flera olika komponenter samverka. Brosket som bekläder benändarna bidrar med stötdämpning och ger en mycket låg friktion vid rörelse. Flera olika ligament och muskler som löper över leden bid
In this volume of “Lecture Notes in Intelligent Transportation and Infrastructure”, we are pleased to present the proceedings of the International Conference “Vision Zero for Sustainable Road Safety in Baltic Sea Region”, which took place in Vilnius, Lithuania, from 5 to 6 December 2018. This event is organized by Vilnius Gediminas Technical University (VGTU) and Lithuanian-Swedish Academy. The miIn this volume of “Lecture Notes in Intelligent Transportation and Infrastructure”, the proceedings of the International Conference “Vision Zero for Sustainable Road Safety in Baltic Sea Region”, which took place in Vilnius, Lithuania, from 5 to 6 December 2018, are presented. The mission of the conference was to promote a more comprehensive approach supporting new ideas, technologies, theories, i
Abstrakt. Ett etablerat MP2RAGE-protokoll för semikvantitativ strukturell hjärn-MRI överfördes frånen 7T MR-skanner till en annan leverantör med jämförbar hårdvara, men motsatt polaritet. På det härsystemet, kan skanningstiden reduceras från 11 till 8 minuter genom elliptisk k-space-sampling. Tre konfigurationerav radiofrekvens (RF) överföring jämfördes (enkelkanal med kvadraturen slits, två och åAbstract. An established MP2RAGE protocol for semi-quantitative structural brain MRI was transferred from one 7T MR scanner to that of another vendor featuring comparable hardware, but opposite polarity. On this system, the scan time could be reduced from 11 to 8 minutes by elliptical k-space sampling. Three configurations of radio-frequency (RF) transmission were compared (single channel with qua
The objective is to study the effect of high voltage pulses on living cells to find the most effective combination of physical parameters to be used in tumour therapy. Four parameters that affect the cell survival are the pulse shape, electric field strength, pulse length and the number of pulses and their cell killing effect were investigated in this work. High voltage square wave or exponentiall
Objective. To report the first clinical evaluation of a new balloon endometrial, thermal destruction system Cavaterm®, for outpatient treatment of menorrhagia. Design. To elucidate possible technical problems during treatment, to evaluate how the patients tolerated the treatment and to judge which patients were suitable for this form of treatment. Main outcome measures. Measurements of bleeding vo
Thermotherapy of the uterus has emerged as an alternative to hysterectomy in the treatment of menorrhagia, from whence it follows that the thermal properties of uterine tissue have become of importance. This study presents measurements of the thermal conductivity and the water content of uterine tissue in vitro. A steady-state thermal conductivity apparatus, based on the comparison of test samples
Objective To estimate, using numerical calculations, the depth of tissue damage in the uterus following balloon thermal endometrial destruction. Design A parameter, therapeutic depth, was defined. This was the maximum depth into the uterine myometrium, from the uterine cavity, at which a predefined temperature was reached after a certain time and with a constant intracavitary temperature. Setting
This study tested the effect of repeated intratumoural injection with recombinant interleukin-2 (rIL-2) and tumour-infiltrating lymphocytes (TILs) on inhibition of growth of breast cancer and on induction of apoptosis of tumour cells. The tumour cell line LDLX43 was used to induce breast cancer in Wistar rats. Group I (10 rats) was the control. Group II (12 rats) received repeated intratumoural in
Background. Treatment of menorrhagia by heat-destruction of the endometrium, intended to be an alternative to hysterectomy, was investigated in an experimental study. Method. A specially designed catheter (Cavaterm™) with a silicone balloon containing a self-regulating heating element is inserted into the uterus, rilled with glycine to a pressure of around 180 mmHg and heated to about 75°C. We inv
Biological effects of electromagnetic fields (EMF) on the blood‐brain barrier (BBB) can be studied in sensitive and specific models. In a previous investigation of the permeability of the blood‐brain barrier after exposure to the various EMF‐components of proton magnetic resonance imaging (MRI), we found that the exposure to MRI induced leakage of Evans Blue labeled proteins normally not passing t
Electrical impedance tomography (EIT) has to be improved in order to become an accepted diagnostic technique in clinical use. The aim of this study is to improve the hardware of this technique and preferably upgrade the current injecting device. Instead of using a constant current generator the idea is to implement a voltage source and measure current accurately, in order to improve the resolution
Three-dimensional electromagnetic calculations for loaded transverse electromagnetic (TEM) transmission cells are presented. Based on those calculations a prediction of the perturbation of the standard uniform field in the TEM-cell, due to the scattering by inhomogeneous structures placed inside the cell cavity, is given. The influence of the dimensions of a lossy structure and its position in the
