Sökresultat

Filtyp

Din sökning på "*" gav 540463 sökträffar

Reduced ROS production triggers arthritis / The role of T cells in arthritis pathogenesis

Popular Abstract in Swedish Brist på fria radikaler kan ge artrit Fagocytiska celler i vårt immunförsvar producerar fria syre-radikaler för att eliminera fagocyterade (uppätna) mikroorganismer. Produktionen av dessa syre-radikaler sker med hjälp av ett enzymkomplex (NADPH oxidas) i cellmembranet samt i membranet på de fagosomer, innehållande mikroorganismer, som bildas i och med fagocytos. MännisThe aim of this thesis is to defend a novel mechanism that triggers arthritis susceptibility in both rats and mice through reduced production of reactive oxygen species (ROS), but also to introduce a novel model for chronic relapsing arthritis. Five papers are included, all of which employ animal models for rheumatoid arthritis and one that also uses animal models for multiple sclerosis. Paper I a

From PowerPoints to Reality - Managing Strategic Change in the Paper Packaging Industry

Popular Abstract in Swedish Den viktigaste frågan för många företag handlar om att trygga långsiktig och framgångsrik utveckling. Men hur säkerställer man ett företags framtid när efterfrågan förändras och kostnaderna för produktionen bara ökar? Hur hanterar man teknikutvecklingen och ändrade maktförhållanden i värdekedjan? Svaren på dessa frågor är ofta nytänkande, innovation och en stark kundoriThis thesis explores and describes strategic change towards increased customer orientation and innovation in the Swedish forest and paper packaging industry, an industry which has been subject to calls for new strategic directions for more than two decades. The large-scale and cost-efficient strategy, which has been the industry's hallmark, is in need of a more customer based and innovative emphas

Extending the nuclear cranking model to tilted axis rotation and alternative mean field potentials

Popular Abstract in Swedish Den föreliggande doktorsavhandlingen handlar om en kärnfysikalisk modell, kallad cranking-modellen, för beräkningar av egenskaper hos snabbt roterande atomkärnor. I modellen tvingas ett deformerat (icke-klotformat) kraftfält att rotera kring en axel genom masscentrum, samtidigt som partiklarna i atomkärnan, protonerna och neutronerna, rör sig i sina s.k. banor inuti denThe nuclear model for three dimensional cranking is extended to include a generalization of the Strutinski renormalization procedure from principal axis cranking to cranking about an tilted axis. A new computer code has been written for realistic, full-scale calculations within the three dimensional cranking model. The code is developed for calculations to produce output of high precision to allow

More than requirements: Applying requirements engineering techniques to the challenge of setting corporate intellectual policy, an experience report

Creation and adoption of corporate policies requires significant commitment of scarce senior management resources. In the absence of processes and tools, convergence upon final policy and may not be achieved in a timely manner. Significant similarities between policy and requirements documents suggest that requirements engineering techniques could be used to generate policy. However, neither evide

Psychotropic Pharmaceuticals in Aquatic Systems: An Ecological Perspective

Popular Abstract in English Psychotropic pharmaceuticals include various groups of chemicals that have been designed to affect neurochemistry in human consumers resulting in changes in cognition, mood, and/or behavior; many target specific receptors and subsequently alter neurotransmitter levels in the central nervous system. The use of pharmaceuticals by consumers results in the release of these Psychotropic pharmaceuticals have been shown to exert a variety of sublethal effects on non-target organisms, even at low concentrations found in the environment (ng/L to µg/L); hence, the aim of my research has been to determine the individual-level effects of psychotropic pharmaceuticals (the selective serotonin reuptake inhibitors sertraline and fluoxetine, and the β-blocker propranolol) on beh

Rum och tid: om tillkomsten av durativ temporal betydelse hos prepositionen "under"

In Early Scandinavian "under" was used as a preposition with the local meaning 'under', 'below' and possibly also (as in German) 'among', 'between'. During the Middle Ages the preposition also aquired the temporal meaning 'during'. It is discussed whether and how the new meaning can be explained from one of the original local meanings.

Packaging handling evaluation methods in the grocery retail industry

The grocery retail industry, with its large product volumes, low margins and fierce competition, is constantly seeking efficiency improvements in its supply chain. The grocery retail industry uses an immense amount of packaging and is directly affected by packaging logistics activities. There is, therefore, a potential for efficiency improvements in the grocery retail supply chain through the inte

Impact of beaconing policies on traffic density estimation accuracy in traffic information systems

Intelligent transport information systems (TIS) are one of the most rapidly emerging applications of wireless vehicular communications using DSRC/WAVE technology. A core function in a TIS is the estimation of traffic density using beacons transmitted by individual vehicles, subsequently used for purposes such as traffic light control or incident detection. In this paper, we conduct an in-depth stu

Local adaptive pigmentation in Asellus aquaticus -effects of UV-radiation and predation regime.

Popular Abstract in Swedish Vattengråsuggan Asellus aquaticus är ett väldigt vanligt ryggradslöst djur i många typer av svenska vatten. Den kan bli över 10 mm stor och äter allt från dött organiskt material till levande alger och växter. Färgen hos gråsuggan kan variera mycket mellan olika miljöer. Den är oftast mörk men kan även vara nästan vit i underjordiska grottpopulationer. Jag har studerat Pigmentation in the freshwater isopod Asellus aquaticus differed between two habitats. Asellus were lighter pigmented in stands of submerged stonewort vegetation, than in nearby reed stands. Moreover, Asellus pigmentation became lighter with time in recently established stonewort stands. Diet or pigment adjustment had minor influence on pigmentation and mating was random with respect to pigmentati

Pour une archéologie des ressources de l’environnement de montagne : l’apport de la microanalyse historique et géographique du site

Here are proposed different studies carried out by the Laboratorio di Archeologia e Storia Ambientale of Genoa University through the use of a geographical historical microanalitical approach to documentary, field and sedimentary sources. The main aim is the reconstruction of different agri-silvo-pastoral practices and of environmental processes connected to the management of mountain resources wi