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Parkinson’s disease (PD) is a progressive neurodegenerative disease, characterized by degeneration of dopaminergic neurons, leading to notable difficulties with one’s movement. Among different treatment options, stem cell replacement therapies have been recognized as an option to not only treat disease symptoms but to address its underlying cause- neuronal degeneration. This can be achieved throug
Lung cancer is one of the most common cancer types and the leading cause of cancer-related mortality. Squamous cell carcinoma (SqCC) of the lung is the second most common histological subtype of lung cancer and the most prevalent in smokers. It is aggressive and hard to treat due to a lack of identified driver mutations and unresponsiveness to treatment. Finding new targeted therapies for SqCC is
Bakgrund: Det finns många olika sätt att beskriva en mångbesökare men gemensamt är att de söker ofta sjukvård mer än andra patienter. Redan år 1954 uppmärksammades det att en liten grupp patienter tog upp en stor del av primärvårdens tid och de kan utgöra upp till 40–50 % av alla vårdbesök. Mångbesökarna är en komplex patientgrupp som ofta har flera kroniska sjukdomar, psykologiska eller sociala p
This thesis explores the role of the architect in the construction process. The project involves designing, projecting, and constructing a 30-square-meter Attefall house in accordance with Swedish building regulations, where the architect assumes full responsibility from concept to completed building. By combining design and construction, the study investigates how the architect’s direct involveme
Introduction: This study focused on characterizing the phase transition behavior in water of thermoresponsive cationic diblock copolymers comprised of a cationic and a non-ionic block. Background: Thermoresponsive polymers, especially block copolymers, have long been of interest to researchers within the field of drug delivery systems. However, more research into their phase transition behavior i
Epilepsy affects a significant portion of people worldwide and still requires alternative treatments due to resistance to anti-seizure medications. Gene therapy offers a promising alternative with several targets already established. Of these, glial cell line-derived neurotrophic factor (GDNF) and its receptor GFR⍺1 are well recognised for their roles in enhancing inhibitory signalling and support
Bakgrund: Med utgångspunkt i mödrahälsovårdens basprogram avgör barnmorskan vad och hur information ska delges under föräldrautbildningen på barnmorskemottagningen. Barnmorskan ska i sitt arbete tillhandahålla evidensbaserad information för att främja gravida kvinnors möjlighet till delaktighet och informerade val. Det finns idag en trend som talar för frångående av den medikaliserade förlossnings
Bakgrund: Hemsjukvården expanderar och att allt fler avancerade hälso- och sjukvårdsinsatser utförs i patientens hem. Flera studier framhåller att patienter värdesätter att få vård i hemmet, men få studier beskriver sjuksköterskornas erfarenheter av att vårda patienter med avancerade vårdbehov i hemsjukvården. Syfte: Syftet med studien var att belysa sjuksköterskors erfarenheter av avancerade vård
Miljöfrågan är högaktuell i dagens samhälle. Företagen och kommunerna tävlar om att vara mest klimatvänliga. Detta leder till en nyfikenhet kring hur byggnadsmaterial kan användas på ett mer effektivt sätt och hur de material som redans används i våra byggnader kan få ett nytt liv på bästa sätt. En stor andel av det som byggdes på 60-talet i Sverige var av tegel, därav har intresset för att kunna Environmental issues are highly topical in today´s society, with companies and municipalities competing to be the most climate friendly. This has sparked an increasing interest in how building material can be used more efficiently and how existing materials within buildings can be given a new life. A large proportion of buildings constructed in Sweden during the 1960s were made of brick, which has
This study investigates how different monetary policy tools have influenced deviations from Covered Interest Parity (CIP) in the USD/SEK 3-month cross-currency basis from 2007 to 2023. Using weekly data and OLS regression with Newey-West standard errors, the analysis evaluates the impact of policy-rate changes, quantitative easing (QE), and central-bank swap lines implemented by the Federal Reserv
Magnesium (Mg) alloys are very light materials that could be useful for many applications. Typical technology for most Mg alloys involves casting followed by solid solution heat treatment. Due to the complexity of some Mg alloy systems, single-step solution treatments cannot achieve dissolution of all secondary phases. Those may require different solutionizing temperatures, creating a need for two
