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Context Substantial diagnostic delay in acromegaly contributes to increased morbidity and mortality. Screening attempts in high-risk groups have yielded few positive cases, underscoring the need for simple and precise prescreening methods. Objective Machine-learning analysis of facial images shows promise for acromegaly detection but requires validation in larger, well-characterized cohorts using

Detta kapitel ger en introduktion till digitala metoder inom idéhistoria, med särskilt fokus på hur studenter kan arbeta med text som data. Vi presenterar centrala begrepp som fjärrläsning, skalbar läsning och temamodellering, samt praktiska verktyg som Transkribus, RegEx och Voyant. Genom konkreta exempel visar vi hur digital textanalys kan identifiera mönster i stora textkorpusar och fungera som

Biodiversity offsetting (BO) is aimed to counterbalance biodiversity impacts from development projects. In Sweden, interest in BO within urban planning has grown since the mid-to-late 1990s, when the approach was first piloted in the municipality of Lomma. Because urban planning often involves non-protected nature, BO is not legally mandated but instead implemented on a voluntary basis. So far, ev

Microplastic (MP) pollution is increasingly recognized as a critical issue in coastal environments, where complex interactions between ocean currents, winds, waves, and human activities govern the transport and deposition of synthetic particles. Although previous studies in Asia have documented MPs accumulation linked to riverine discharge, tourism pressures, and monsoonal circulation, limited wor

The field of high energy physics (HEPs) has seen a marked increase in the use of machine learning (ML) techniques in recent years. The proliferation of applications has revolutionised many aspects of the data processing pipeline at collider experiments including the Large Hadron Collider (LHC). In this whitepaper, we discuss the increasingly crucial role that ML plays in real-time analysis (RTA) a

introduction to a reader with texts by Hannah Arendt, selected by Gertrud Sandqvist

Background Previous studies of minimally invasive liver surgery described results and experiences in high-volume centres and early adopters, but data on national levels are lacking. This study evaluated the implementation and outcomes of minimally invasive liver surgery in Sweden over a 15-year period, with a focus on colorectal liver metastases. Methods Data from patients undergoing liver surgery

Selective TDP-43 overexpression in oxytocin neurons in the paraventricular nucleus of the hypothalamus causes a decrease in oxytocin-immunopositive cells compared to uninjected mice. AAV-mediated TDP-43 overexpression in oxytocin neurons does not appear to be a major driver of behavioural and metabolic phenotypes in mice.

Background: The Swedish National Board of Health and Welfare centralized the surgical care of patients with anorectal malformations from four to two centres in 2018. This retrospective review compares short-term complications after anorectal reconstruction before and after centralization. Methods: Hospital records of all infants in Sweden who underwent reconstruction of an anorectal malformation b

Reader with texts by Hannah Arendt, selected by Gertrud Sandqvist

Controlled and sequence-selective DNA cleavage plays a crucial role in biomolecular engineering and nucleic acid technologies. Here, we report the development of cerium-coordinated catalytic hydrogel nanoparticles (Ce-CHNP) that exhibit single-strand-selective nuclease activity. Ce-CHNP was synthesized via a one-step polymerization process in which Ce(IV) coordinated with N-hydroxymethyl acrylamid

Purpose Gangliogliomas are highly epileptogenic tumors that are common in epilepsy surgery. The main aim of this study was to investigate whether the outcome of Anti-seizure medication (ASM) withdrawal differed between patients undergoing ganglioglioma surgery in an epilepsy surgery program compared with those who underwent surgery in other surgical programs. We also investigated which factors inf

Optical genome mapping (OGM) enables high-resolution detection of structural variants (SVs) and copy number aberrations (CNAs) using ultralong DNA molecules and minimal bioinformatics processing. Its diagnostic utility in solid tumors remains underexplored. Whole-genome sequencing (WGS) offers comprehensive variant detection but is resource intensive. This study presents a technical benchmarking o

Arthropod neurobiology has been studied overwhelmingly in insects, leaving the molecular basis of sensory systems in non-insect arthropods poorly understood; addressing this gap is necessary to enrich our knowledge of these understudied groups. Spiders possess sensory systems distinct from insects, with numerous synapses in peripheral sensory nerves, positioning them as an ideal model for investig

We combine existing perturbative results to show that a precise analytic determination of the charm-quark contribution to the hadronic light-by-light (HLbL) part of the muon anomalous magnetic moment is possible. Working in the MS‾ scheme, we include the NLO O(αs) correction, which significantly reduces the residual renormalization-scale dependence and the perturbative uncertainty. Our final resul

Unseen Sights: Magic, Modernity, and Childhood in Children’s Urban Fantasy explores and analyses the genre of children’s urban fantasy. Drawing upon a combination of fantasy, urban fantasy, and children’s literature scholarship, the thesis considers how children’s urban fantasy works – investigating both its forms and functions, and how it performs work in the world.The genre is analysed both sync

Objectives To examine the associations between socioeconomic position (SEP) and the incidence of serious hand infections—pyogenic flexor tenosynovitis (PFT) and septic arthritis (SA)—as well as risks of opioid overuse following diagnosis using nation-level data. Design In a registry-based nationwide retrospective cohort study, (1) associations between SEP and incidence of PFT/SA; (2) SEP and infec