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Charged Higgs bosons produced either in top-quark decays or in association with a top quark, subsequently decaying via (Formula presented), are searched for in (Formula presented) of proton-proton collision data at (Formula presented) recorded with the ATLAS detector. Depending on whether the top quark is produced together with the (Formula presented) decays hadronically or semileptonically, the s

Inflammatory responses to acute stimuli are proposed to regulate sleep, but the relationship between chronic inflammation and habitual sleep duration is elusive. Here, we study this relation using genetically predicted level of chronic inflammation, indexed by CRP and IL6 signaling, and self-reported sleep duration. By Mendelian randomization analysis, we show that elevated CRP level within <10 mg

Microplastics and nanoplastics (MNPs) are ubiquitous environmental pollutants with increasing implications for human health. While their presence in human tissues is established, the molecular mechanisms driving their potential neurotoxicity remain unclear. This study investigates the impact of polystyrene (PS) on amyloid protein misfolding and cellular metabolism using Optical Photothermal Infrar

Top-quark pair production is observed in lead-lead ((Formula presented)) collisions at (Formula presented) at the Large Hadron Collider with the ATLAS detector. The data sample was recorded in 2015 and 2018, amounting to an integrated luminosity of (Formula presented). Events with exactly one electron and one muon and at least two jets are selected. Top-quark pair production is measured with an ob

Purpose: To illustrate the potential bias caused by imaging gradients in correlation MRI sequences using longitudinal magnetization storage (LS) and examine the case of filter exchange imaging (FEXI) yielding maps of the apparent exchange rate (AXR). Methods: The effects of imaging gradients in FEXI were observed on yeast cells. To analyze the AXR bias, signal evolution was calculated by applying

In 2022 and 2023, the Large Hadron Collider produced approximately two billion hadronic interactions each second from bunches of protons that collide at a rate of 40 MHz. The ATLAS trigger system is used to reduce this rate to a few kHz for recording. Selections based on hadronic jets, their energy, and event topology reduce the rate to Ô(10) kHz while maintaining high efficiencies for important s

ALICE is a large experiment at the CERN Large Hadron Collider. Located 52 meters underground, its detectors are suitable to measure muons produced by cosmic-ray interactions in the atmosphere. In this paper, the studies of the cosmic muons registered by ALICE during Run 2 (2015–2018) are described. The analysis is limited to multimuon events defined as events with more than four detected muons (Nµ

Using three independent archival sources, we previously documented substantial declines in stunting and wasting in Portugal during the mid-twentieth century. This note revisits the original evidence, clarifies the descriptive scope of our analysis, and situates the observed anthropo-metric changes within the broader evolution of public health, nutrition, and social policy in Portugal. We show that

OBJECTIVES: Nociception monitoring during general anesthesia is evolving to improve intraoperative management and postoperative outcomes. While opioid-based anesthesia (OBA) remains widely used for its strong antinociceptive effects, concerns about opioid-induced adverse effects have fueled interest in opioid-free anesthesia (OFA) approaches. This study aimed to compare perioperative and postopera

We document a substantial glass ceiling in the Swedish labor market: women constitute less than 20% within the top 1% of the earnings distribution. Using a structural micro-founded model of a dual earner household with learning-on-the-job, we link this to the child penalty. While on parental leave, women accumulate less human capital on the job, get promoted to a lesser extent, and hence are less

Among the headlines:Did the Directive trigger any other discussion in the area of CB? Shrinking share of workplace union clubs and union representativesCollective agreements on co-determination ‘light’Reduced co-determination and reduced working hoursProblems with labour law requirements in public procurementsBig enterprises in new industries resist collective agreements, but very few new collecti

BACKGROUND: Obesity affects over 40% of US adults, with severe obesity on the rise. Despite recognition of obesity as a chronic disease, it remains underdiagnosed and undertreated. Access to evidence-based obesity treatment is limited, leading to increased obesity severity and related complications. Barriers to obesity treatment include socioeconomic disparities, limited clinician training, stigma

Frequency-dependent diffusion–relaxation distribution MRI provides information beyond the traditional voxel-averaged metric that may better characterize the microstructural features of biological tissue. Frequency-dependent multidimensional (ωMD) MRI reproducibility has been established in clinical settings, but has yet to be thoroughly evaluated under preclinical conditions, where superior ha

Importance: While clinical disease stages remained largely unchanged in the 2024 update of the Alzheimer disease (AD) criteria, tau-positron emission tomography (PET) was introduced as a core biomarker and its spatial extent was incorporated into the revised biological stages of the disease. It is important to consider both the clinical and the biological stages and understand their discrepancies.