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Background: We recently demonstrated that increased expression of the RNA-binding protein RBM3 is associated with a favourable prognosis in breast cancer. The aim of this study was to examine the prognostic value of RBM3 mRNA and protein expression in epithelial ovarian cancer (EOC) and the cisplatin response upon RBM3 depletion in a cisplatin-sensitive ovarian cancer cell line. Methods: RBM3 mRNA

Abstract Disorders in mineral metabolism and secondary hyperparathyroidism (sHPT) are well known complications in patients with chronic kidney disease (CKD). Hyperparathyroidism (HPT) persists in a majority of patients after kidney transplantation (KTx). Parathyroidec-tomy (PTX) is indicated in patients who are resistant to medical therapy both before and after KTx. Overall aims of this thesis we

Political candidates often believe they must focus their campaign efforts on a small number of swing voters open for ideological change. Based on the wisdom of opinion polls, this might seem like a good idea. But do most voters really hold their political attitudes so firmly that they are unreceptive to persuasion? We tested this premise during the most recent general election in Sweden, in which

The broad aim of this thesis is to explain the fundamental themes and function of Swedish field sermons and field prayers, and so to re-examine the view in earlier research that field sermons were primarily ‘Old Testamentary’ in nature. Inspired by more recent international research, I hold that the sermons’ basic functions were twofold: discipline and comfort. What matters, is to understand the d

We have developed and characterized a hard x-ray accumulating streak camera that achieves subpicosecond time resolution by using single-photon counting. A high repetition rate of 2 kHz was achieved by use of a readout camera with built-in image processing capabilities. The effects of sweep jitter were removed by using a UV timing reference. The use of single-photon counting allows the camera to re

Background: Ghrelin, an endogenous ligand for the growth hormone secretagogue receptor (GHSR), has two major functions: the stimulation of the growth hormone production and the stimulation of food intake. Accumulating evidence also indicates a role of ghrelin in cancer development. Methods: We conducted a case-control study to examine the association of common genetic variants in the genes coding

The most commonly used technology currently used for autoradiography is storage phosphor screens, which has many benefits such as a large field of view but lacks particle-counting detection of the time and energy of each detected radionuclide decay. A number of alternative designs, using either solid state or scintillator detectors, have been developed to address these issues. The aim of this stud

Fermented milk is commonly eaten during breakfast or as a snack between meals either in one-portion cups or from a bowl with a spoon. Approximately 5-10% of the fermented milk remains in the packages upon pouring, which during the last years, has received attention in public media as newspapers and television. This is a problem, not only from an economical point of view, but also from an ecologica

In order to explore verbal-nonverbal integration, we investigated the influence of cognitive and linguistic ability on gaze behavior during spoken language conversation between children with mild-to-moderate hearing impairment (HI) and normal-hearing (NH) peers. Ten HI-NH and 10 NH-NH dyads performed a referential communication task requiring description of faces. During task performance, eye move

P>Background: Studies of the nasal lavage fluid proteome have previously identified proteins differently expressed in patients with symptomatic allergic rhinitis, e.g. S100A7, prolactin-inducible protein (PIP), wingless-type MMTV integration site family, member 2B (WNT2B), Charcot-Leyden crystal protein (CLC) and palate lung nasal epithelial clone (PLUNC). The aim of the present study was to inves

Current sampling of genomic sequence data from eukaryotes is relatively poor, biased, and inadequate to address important questions about their biology, evolution, and ecology; this Community Page describes a resource of 700 transcriptomes from marine microbial eukaryotes to help understand their role in the world's oceans.

I religionernas värld har man alltid varit medveten om vilken betydelse ljud och tystnad har för vårt välbefinnande. Ibland framhävs tystnaden; i andra fall kan det röra sig om det monotona ljude av exempelvis en upprepad bön. Sådana övningar blir föremål för en psykologisk kommentar.

I denna artikel tar jag upp ett berättargrepp, den narrativa syllepsen, som inte fått någon större uppmärksamhet i litteraturteorin hittills. Den narrativa syllepsen definierades först av den franske litteraturteoretikern Gérard Genette år 1972 som ett berättargrepp där olika temporaliteter smälter samman. Begreppet har dock inte använts i någon större utsträckning därefter, vilket jag anser vara In this article I discuss a narrative device, the narrative syllepsis, which has not received much attention in literary theory until now. The narrative syllepsis was first defined by French literary theorist Gérard Genette as a narrative device where different temporalities merge. The concept has however not been used att a larger scale after Genette, something I find surprising taking into consi

This article aims to explore critically the role of an action research team in the social construction of interorganizational collaboration aimed at transgressing organizational and professional boundaries. We argue that the new relationships, actor conceptions and in some cases forms of work organization arising from the change process have been socially constructed through the discursive interve

A search for events with large missing transverse momentum, jets, and at least two tau leptons has been performed using 2 fb(-1) of proton-proton collision data at root s = 7 TeV recorded with the ATLAS detector at the Large Hadron Collider. No excess above the Standard Model background expectation is observed and a 95% CL upper limit on the visible cross section for new phenomena is set, where th

Genomgång av illustrationer till Axel Wallengrens "fakiriska" verk och hur dessa förhåller sig dels till själva texterna och dels till dessas upphovsman.

Popular AbstractAvhandlingens titel Den goda viljans paradoxer skall förstås på följande sätt. I utredningar och propositioner hävdar utredare, skolpolitiker och administratörer att lärarna skall bemyndigas, det vill säga de skall tillskrivas ett mandat i skolan. Detta mandat skall ge lärarna ett visst självständigt beslutsfattande i en ny mötesform som kallas arbetsenheter. Denna mötesform stipulThe theory and practice of reform as reflected in teachers’ experience of meetings in schools. This empirical study has been carried out in a coeducational school for pupils up to the age of 16 ("grundskola") during the school years 1988-89 up to and including 1991/92. In this study 26 teachers and five school administrators - head teachers and deputy-head teachers - have been interviewed. Person