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Background: The role of cystectomy in synchronous oligometastatic bladder cancer is unclear. Objective: To describe a population-based consecutive cohort with primary oligometastatic bladder cancer (M1a or M1b) treated with curative intent. Methods: Twenty consecutive patients with primary stage M1a or M1b bladder cancer subjected to induction chemotherapy and radical cystectomy 2013–2024 in the S

Drawing upon meticulous ethnographic analysis and unique data sources, this book dissects the multifaceted challenges and occasional victories encountered by both educators and detained youth in Sweden. Originally published in Swedish, this book provides fresh insights into a crucial aspect of youth care and education. Theoretical underpinnings draw from ethnomethodology’s focus on members’ accoun

Over the past 50 years, the number of tendon ruptures has been increasing. Ruptures may be traumatic, or as a response to long term tendinopathy including e.g. inflammation, altered structure and composition of the tendon. Tendons are primarily made up of water and load bearing collagen molecules that hierarchically assemble into fibrils, aggregate into fibres, that combine into fascicles and even

Full-duplex (FD) communication improves spectral efficiency by allowing simultaneous transmission and reception on the same frequency band. This paper analyzes a two-tier network consisting of macrocells and picocells, where base stations (BSs) operate in FD mode while users operate in half-duplex (HD) mode. However, interference remains a major challenge in these systems, significantly impacting

Background and objective: Prostate-specific membrane antigen (PSMA) positron emission tomography/computed tomography (PET/CT) is an evolving diagnostic tool for prostate cancer. There is a need to harmonise existing guidelines and reporting recommendations for PSMA PET/CT. The Standardised PSMA PET/CT Analysis and Reporting Consensus (SPARC) project aims to consolidate classifications and recommen

Federated Learning (FL) enables decentralized training of neural networks across multiple hospitals or patients while preserving data privacy. However, FL schemes typically assume data is independent and identically distributed (IID) while healthcare data can be highly heterogeneous. To address this, we propose Interpretable Personalized Federated Learning (IPFL), a novel framework that allows pat

In this study, we investigate integrating eye tracking with auditory attention decoding (AAD) using portable EEG devices, specifically a mobile EEG cap and cEEGrid, in a preliminary analysis with a single participant. A novel audiovisual dataset was collected using a mobile EEG system designed to simulate real-life listening environments. Our study has two main objectives: (1) to use eye tracking

Permanent Magnet Synchronous Motors (PMSMs) are becoming increasingly popular in traction applications. PMSMs have gained popularity due to their efficiency, compactness and excellent features related to control. This is mainly because of the permanent magnet placement in the rotor, which negates any additional rotor excitation, hence reducing energy losses considerably. This makes them more effic

Transition to a circular plastic economy requires rethinking of the entire value chain from the raw materials and energy used for production, to material design, collection and recycling. Our focus has mainly been on polyesters as they span a wide scope of applications and properties ranging from durable to biodegradable. This presentation will highlight our work on designing and developing the bi

Probed language-based assessments, where individuals describe their states using open-ended responses analyzed with Artificial Intelligence, have shown great promise for written language. But emotions are also conveyed through spoken language which might provide further assessment power to this method. Participants (N=645) were randomly assigned to watch a video clip of a church, shopping mall, or

Background: Decades of progress in care and treatment for congenital heart disease (CHD) has gradually shifted the research focus from initial survival to long-term prognosis and the ageing of adults with CHD. Knowledge about the ageing adult with CHD will guide interventions to safeguard the quality of life across the life course. The present study compares the prevalence of frailty and cognitive

The maximum drawdown of a stochastic process is the largest peak-to-troughdecline observed over a given horizon [0, T]. Using arguments from extremevalue theory, we derive the limiting distribution of the maximum drawdown fora Brownian motion with positive drift as T → ∞. We show that, after suitablecentering and scaling, the maximum drawdown converges in distribution to theGumbel law.

BakgrundPrimärvården utgör den första linjen av vård och stöd för personer med psykisk ohälsa. Verksamheten är i huvudsak inriktad på diagnostik, medicinsk behandling och symtomlindring. Tillgången till denna vård upplevs emellertid som utmanande både av patienter och vårdgivare. En fördjupad förståelse av den levda erfarenheten av mötet med primärvården kan bidra till utvecklingen av mer individaBackground: Primary health care is in the unique position of being a first level of support and care to individuals with mental health problems. The focus in this service is on diagnosis, medical treatment, and symptom reduction. However, to access it is perceived as challenging by both patients and providers. An increased understanding of the lived experience of encountering primary health care m

Phage collections are essential tools for discovering and dissecting bacterial anti-phage defense systems. Here, we report the isolation, characterization, and annotated genome sequences of five environmental Escherichia coli-infecting phages, obtained during the 2023 Fundamentals of Basic and Applied Phage Biology course at Lund University. The phages were isolated using a motile E. coli K-12 BW2

Dementia is a decline in cognitive function that impairs a person’s previous level of social and occupational function. Dementia is a very common medical condition that can result from diverse causes. Dementias are classified based on common clinical, genetic, and neuropathological features. The most common cause of dementia is Alzheimer’s disease. Other major classes of disorders that cause demen

BackgroundAmyloid-β peptides (Aβ) applied to Alzheimer's disease (AD) brain bind to amyloid plaques (APs) and this binding is saturable. Meanwhile, anti-immunoglobulin G (IgG) antibodies label APs. Considering the saturable binding of Aβ to APs and the localization of IgGs in APs, specific binding proteins (BPs) for the applied Aβ could be anti-Aβ IgG antibodies (anti-AβAbs) in APs.ObjectiveOur ob

Background: In 2015, a proton therapy (PT) facility was established in Sweden with one aim being to ensure access for all children expected to benefit from PT. Despite potential dosimetric advantages and full subsidisation, PT is not always selected. This study explores reasons for choosing alternative radiotherapy (RT) modalities in a paediatric population. Material and methods: RT courses delive

OBJECTIVE: To synthesise evidence related to the dissemination and implementation (D&I) of injury prevention interventions for female, woman and/or girl (female/woman/girl) athletes.DESIGN: Scoping review.DATA SOURCES: MEDLINE, APA PsycInfo, Cochrane Databases for Systematic Review, Cochrane Central Register for Controlled Trials Registry, EMBASE, CINAHL, SPORTDiscus, ERIC, ProQuest Dissertati

Background: Allergic contact dermatitis (ACD) caused by isothiazolinones is a growing concern, particularly in consumer products. Octylisothiazolinone (OIT) is a potent sensitiser and commonly used as a preservative in rubbers, plastics and coatings, including those found in headphones. Despite increasing regulations on isothiazolinones in cosmetics, their presence in wearable devices remains unde

A multi-variable adaptive controller is derived as the explicit solution to a minimax dynamic game. The minimizing player selects the control action as a function of past state measurements and inputs. The maximizing player selects disturbances and model parameters for the underlying linear time-invariant dynamics. This leads to a Bellman equation that can be solved explicitly for the case with un