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Over the past few years, wireless mesh networks are emerging as a strong technology for cheap wireless coverage. Despite recent advances in wireless mesh networking, many research challenges remain in all protocol layers. Since a mesh network usually has very different characteristics than those of current fixed mobile networks, traditional fixed deployments such as those in cellular IP and HMIP w

This thesis consists basically of two parts. They are, however, interrelated by the fact that both parts concerns modelling of catalytic reaction systems and also by the fact that in both parts, spectral methods are used for simulation. The first part describes the numerical treatment of the dispersion model. The model is used to simulate a packed-bed reactor producing formaldehyde from methanol w

Context: Obesity and cardiometabolic diseases are associated with higher long-term glucocorticoid levels, measured as scalp hair cortisol (HairF) and cortisone (HairE). Cardiometabolic diseases have also been associated with copeptin, a stable surrogate marker for the arginine-vasopressin (AVP) system. Since AVP is, together with corticotropin-releasing hormone (CRH) an important regulator of the

Background: Personal recovery is associated with many significant health-related factors, but studies exploring associations between activity factors and personal recovery among service users are scarce. The aims of this study were hence to; 1) investigate if various aspects of activity may mediate change in recovery while also acknowledging clinical, sociodemographic and well-being factors; 2) ex

Frequency recognition algorithm for multiple exposures (FRAME) is a single-exposure imaging technique that can be used for ultrafast videography, achieved through rapid illumination with spatially modulated laser pulses. To date, both the limit in sequence length as well as the relation between sequence length and image quality are unknown for FRAME imaging. Investigating these questions requires

Fine-tuning of insulin release from pancreatic β-cells is essential to maintain blood glucose homeostasis. Here, we report that insulin secretion is regulated by a circular RNA containing the lariat sequence of the second intron of the insulin gene. Silencing of this intronic circular RNA in pancreatic islets leads to a decrease in the expression of key components of the secretory machinery of β-c

We introduce a family of boundary confinements for Coulomb gas ensembles, and study them in the two-dimensional determinantal case of random normal matrices. The family interpolates between the free boundary and hard edge cases, which have been well studied in various random matrix theories. The confinement can also be relaxed beyond the free boundary to produce ensembles with fuzzier boundaries,

Duplicative horizontal gene transfer may bring two previously separated homologous genes together, which may raise questions about the interplay between the gene products. One such gene pair is the “native” PgiC1 and “foreign” PgiC2 in the perennial grass Festuca ovina. Both PgiC1 and PgiC2 encode cytosolic phosphoglucose isomerase, a dimeric enzyme whose proper binding is functionally essential.

Background: Genome-wide association studies (GWAS) have proven successful in predicting genetic risk of disease using single-locus models; however, identifying single nucleotide polymorphism (SNP) interactions at the genome-wide scale is limited due to computational and statistical challenges. We addressed the computational burden encountered when detecting SNP interactions for survival analysis,

The sexes may have different optima in cognitive traits due to differences in life history strategies and the expense of investing in metabolically costly brain tissue. However, given genetic correlations, each sex could be constrained from reaching its cognitive optimum due to intralocus sexual conflict. We compared learning performance of two male alternative reproductive tactics and females fro

The article analyzes the varied meanings historically associated with concepts of voluntarism in relation to social relief as they were articulated by changing moral elites in Denmark from the late nineteenth century until the present. Concepts of voluntarism have historically constituted “normative counterconcepts” that link voluntary practices to desired futures in opposition to alternative mode

Walking is a simple form of exercise, widely promoted for its health benefits. Self-reported walking pace has been associated with a range of cardiorespiratory and cancer outcomes, and is a strong predictor of mortality. Here we perform a genome-wide association study of self-reported walking pace in 450,967 European ancestry UK Biobank participants. We identify 70 independent associated loci (P <