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The drumlin field and the geomorphology of the Mulajokull surge-type glacier, central Iceland
Here we present a new geomorphological map of the active drumlin field and the forefield of Millajokull, a surgetype outlet glacier, Iceland. The map is based on aerial photographs taken in 1995 and LiDAR data recorded in 2008. Mapping was done using ArcGIS 10 software on orthorectified imagery, LiDAR data and digital elevation models. The mapped landforms were initially identified on the aerial i
Impact of nutrients on peatland GPP estimations using MODIS time series data
Time series of satellite sensor-derived data can be used in the light use efficiency (LUE) model for gross primary productivity (GPP). The LUE model and a closely related linear regression model were studied at an ombrotrophic peatland in southern Sweden. Eddy covariance and chamber GPP, incoming and reflected photosynthetic photon flux density (PPFD), field-measured spectral reflectance, and data
Transferability of conformational dependent charges from protein simulations
We have studied the transferability of atomic charges for proteins, fitted to the quantum mechanical electrostatic potential and extensively averaged over a set of structures sampled by molecular dynamics (MD) and over all residues of the same kind in the protein sequence (xAvESP). Previously, such charges were obtained for one single protein (avidin). In this study, we use five additional protein
Schrodinger operators on regular metric trees with long range potentials: Weak coupling behavior
Consider a regular d-dimensional metric tree Gamma with root o. Define the Schrodinger operator -Delta -V, where V is a non-negative, symmetric potential, on Gamma. with Neumann boundary conditions at o. Provided that V decays like |x|(-gamma) at infinity, where 1 <= gamma <= d <= 2, gamma not equal 2, we will determine the weak coupling behavior of the bottom of the spectrum of -Delta -V. In othe
Mechanisms of pathogenesis, infective dose and virulence in human parasites
Cognitive Function in Young Men and the Later Risk of Fractures
Dementia has been associated with an increased risk of fractures. These associations may be explained by an impaired cognitive function, as well as comorbid illness and toxic reaction from drugs. To investigate whether cognitive function in young, healthy individuals already affects the risk of fractures, overall cognitive function scores were calculated from four cognitive tests accomplished duri
The Importance of Continuity in Inhaler Device Choice for Asthma and Chronic Obstructive Pulmonary Disease.
Inhaled therapies are central to the treatment of asthma and chronic obstructive pulmonary disease. Physicians consider many factors when selecting the most appropriate inhaler device, including device efficacy and the cost to the health care system. This review aims to discuss the factors that are important when considering inhaler devices and the importance of continuity in the choice of inhaler
Shape Coexistence in the Neutron-Deficient Even-Even Hg182-188 Isotopes Studied via Coulomb Excitation.
Coulomb-excitation experiments to study electromagnetic properties of radioactive even-even Hg isotopes were performed with 2.85 MeV/nucleon mercury beams from REX-ISOLDE. Magnitudes and relative signs of the reduced E2 matrix elements that couple the ground state and low-lying excited states in Hg182-188 were extracted. Information on the deformation of the ground and the first excited 0+ states
Contribution of ship traffic to aerosol particle concentrations downwind of a major shipping lane
Particles in the atmosphere are of concern due to their toxic properties and effects on climate. In coastal areas, ship emissions can be a significant anthropogenic source. In this study we investigated the contribution from ship emissions to the total particle number and mass concentrations at a remote location. We studied the particle number concentration (12 to 490 nm in diameter), the mass con
Bedside Evaluation of Cerebral Energy Metabolism in Severe Community-Acquired Bacterial Meningitis
Mortality and morbidity have remained high in bacterial meningitis. Impairment of cerebral energy metabolism probably contributes to unfavorable outcome. Intracerebral microdialysis is routinely used to monitor cerebral energy metabolism, and recent experimental studies indicate that this technique may separate ischemia and non-ischemic mitochondrial dysfunction. The present study is a retrospecti
Variation in crystalline architectures through supramolecular interactions in copper(II) complexes with tridentate N2O donor Schiff bases
Three copper(II) complexes, [Cu(L-1)(H2O)(ClO4)]0.5H(2)O (1), [Cu(L-2)(H2O)(ClO4)]0.5H(2)O (2), and [Cu(L-2)(NCNC(OCH3)NH2)]ClO4 (3), where HL1=4-bromo-2-(-(quinolin-8-ylimino)methyl)phenol and HL2=1-(-(quinolin-8-ylimino)methyl)naphthalen-2-ol, have been prepared and characterized by elemental analysis, IR, UV-vis and fluorescence spectroscopy and single-crystal X-ray diffraction studies. The cop
Dioxygenase from Aspergillus fumigatus MC8: molecular modelling and in silico studies on enzyme-substrate interactions
Flavoenzymes have been extensively studied for their structural and mechanistic properties because they find potential application as industrial biocatalysts. They are attractive for biocatalysis because of the selectivity, controllability and efficiency of their reactions. Some of these enzymes catalyse the oxidative modification of protein substrates. Among them oxygenases (monoxoygenases and di
Where the Two Logics of Institutional Theory and Entrepreneurship Merge: Family Business Owners Caught in the Past or Stuck in the Future?
Rapid and sustained health utility gain in anti-TNF treated inflammatory arthritis. Observational data during seven years in southern Sweden.
BACKGROUND: Rheumatoid arthritis (RA), psoriatic arthritis (PsA), and other spondylarthritides (SpA) impose great impact on the individual in addition to the costs on society, which may be reduced by effective pharmacological treatment. Industry independent health economic studies should complement studies sponsored by industry. OBJECTIVE: To study secular trends in baseline health utilities in pa
Carbamylation of immunoglobulin abrogates activation of the classical complement pathway
Post-translational modifications of proteins significantly affect their structure and function. The carbamylation of positively charged lysine residues to form neutral homoitrulline occurs primarily under inflammatory conditions through myeloperoxidase-dependent cyanate (CNO-) formation. We analyzed the pattern of human IgG(1) carbamylation under inflammatory conditions and the effects that this m
Inhibitor Eradication In Acquired Haemophilia A Final Results of European Acquired Haemophilia Registry (EACH2)
Media Coverage Crisis Exploitation Characteristics: A Case Comparison Study
The emerging complexity of gene fusions in cancer.
Structural chromosome rearrangements may result in the exchange of coding or regulatory DNA sequences between genes. Many such gene fusions are strong driver mutations in neoplasia and have provided fundamental insights into the disease mechanisms that are involved in tumorigenesis. The close association between the type of gene fusion and the tumour phenotype makes gene fusions ideal for diagnost
W41/W41 blastocyst complementation: a system for genetic modeling of hematopoiesis.
We report a rapid and highly efficient approach to generate mice in which the hematopoietic system is derived from embryonic stem (ES) cells. We show that ES cells injected into blastocysts from the c-kit deficient W41/W41 mouse strain have a clear advantage over the W41/W41 blastocyst-derived inner cell mass cells in founding the hematopoietic system. Fetal liver HSCs from W41/W41 blastocyst comp
